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Ultratrace Minerals
Published in Luke R. Bucci, Nutrition Applied to Injury Rehabilitation and Sports Medicine, 2020
In 1989, Pardue and others injected turkey eggs with 250 or 500 μg of boron as sodium tetraborate.1011 Tibial weight, tibial length, tibial calcium content, and bone ash were all significantly increased by boron addition. In 1992, Elliot and Edwards from the Department of Poultry Science of the University of Georgia reported on the interaction of different levels of dietary boron with calcium and vitamin D (cholecalciferol) in broiler cockerels fed tibial dyschondroplasia-inducing basal diets.1012 Dietary boron at intakes of 0,5, 10,20,40, and 80 mg/kg had no influence on weight gain, feed efficiency, or plasma mineral levels. Boron intakes of 5 and 10 mg/kg were associated with increased bone ash. However, varying dietary calcium and vitamin D intakes along with boron intakes of 0, 3, or 40 mg/kg did not show any obvious interactions.
Notes on Cancer
Published in Nate F. Cardarelli, The Thymus in Health and Senescence, 2019
Malignant tumors are also absent in Alaskan55 and Peruvian mummies.56 Some small amount of trace metal work has been performed with interesting results. Zimmerman et al., noted that a Peruvian mummy has about 2 ppm lead in bone ash while modern man shows up to 60 ppm.56 Analysis of the bones of an Egyptian mummy of about 170 B.C. showed 0.6 ppm lead and 0.43 ppm mercury as compared to 6 to 18 ppm Pb (by wet weight) and up to 1 ppm Hg in man today.54 Anglo-saxon and Pueblo indian skulls have been examined and a number of cases of osteoma discovered.57 However the admittedly crude incidence values are nowhere near what we experience today.
Trace Metals in Growth and Sexual Maturation
Published in Owen M. Rennert, Wai-Yee Chan, Metabolism of Trace Metals in Man, 2017
There is no impairment of the calcification process due to manganese deficiency. The volume and the gross composition of bone ash are also not reduced in this condition. Skeletal maturation is retarded due to an inhibition of endochondral osteogenesis at the epiphyseal cartilages.
Predicting the effective compressive modulus of human cancellous bone using the convolutional neural network method
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2023
Yongtao Lu, Zhuoyue Yang, Hanxing Zhu, Chengwei Wu
In the definition above, an upper threshold value of 1200.00 mg/cm3 was set to eliminate the influence of artificially high grayscale values. On the other hand, the material with the bone ash density lower than 400.0 mg/cm3 (Crawford et al. 2003) was regarded as bone marrow, and the corresponding Poisson's ratio was set to 0.49. The Poisson’s ratio of bone elements was set to 0.30. An example of a heterogeneous FE model is shown in Figure 2b, in which the color map shows the distribution of Young's modulus of the tissue and the black area represents the pores.
Rutin nanosuspension for potential management of osteoporosis: effect of particle size reduction on oral bioavailability, in vitro and in vivo activity
Published in Pharmaceutical Development and Technology, 2020
Sonia Gera, Venkatesh Pooladanda, Chandraiah Godugu, Veerabhadra Swamy Challa, Jitendra Wankar, Sujatha Dodoala, Sunitha Sampathi
The physical parameters of the femur bone, its length and diameter didn’t show a significant difference (Table 5). The bone density, its dry weight, length, and diameter were decreased significantly in the OVX group as compared to the sham group. The treatment with RLX, RUT and RUT-NS has restored the bone density near to the normal. The bone ash weight, calcium and phosphorus levels decreased significantly in the OVX group than the sham group. Treatment firmly assists in restoring the lost bone mineral content.
Assessment of tricalcium phosphate/collagen (TCP/collagene)nanocomposite scaffold compared with hydroxyapatite (HA) on healing of segmental femur bone defect in rabbits
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Mahmoud Mohseni, Alireza Jahandideh, Gholamreza Abedi, Abolfazl Akbarzadeh, Saeed Hesaraki
Tricalcium phosphate (TCP) is a tertiary calcium phosphate also known as bone ash [Ca3(PO4)]. It serves as a rich source for calcium and phosphorus, which can be easily assimilated and absorbed. Beta-TCP is highly biocompatible and creates a resorbable interlocking network within the defect site to promote healing [5,6].