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Utilization of Fisheries' By-Products for Functional Foods
Published in Se-Kwon Kim, Marine Biochemistry, 2023
Muhamad Darmawan, Nurrahmi Dewi Fajarningsih, Sihono, Hari Eko Irianto
Calcium has an important role in numerous health functions such as strengthening the bone and teeth, nerve function and cofactor of many enzymatic reactions (Kim and Jung, 2007). The phosphopeptide content in fishbone could increase the bioavailability of calcium by inhibiting the formation of insoluble calcium phosphate (Hoang et al., 2003). The intake of fishbone phosphopeptides increased Ca bioavailability and prevent Ca deficiency (Jung et al., 2006). It was also reported that tuna bone powder supplementation was able to improve the microstructure of maternal bone and increase the density of bone minerals in lactating rats and their offspring (Suntornsaratoon et al., 2018).
Hyperthyroidism
Published in Charles Theisler, Adjuvant Medical Care, 2023
Calcium: Too much thyroid hormone can prevent the body from absorbing calcium into the bones.2 The Institute of Medicine recommends 1,000 milligrams of calcium a day for adults ages 19-50 and men ages 51-70. That calcium recommendation increases to 1,200 mg/day for women 51 or older and men who are 71 or older.
Bone Health
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
Calcium Supplements: The two primary forms of calcium used in supplements are calcium citrate and calcium carbonate. Because calcium carbonate requires stomach acid for absorption, it’s best to take this product with food. Calcium citrate supplements are absorbed more easily than calcium carbonate. They can be taken on an empty stomach and are more readily absorbed by people who are taking acid-reducing medications for heartburn.
Nonlinearity association of serum calcium with the risk of anaemia in US adults
Published in Hematology, 2023
Zeling Chen, Jing Xu, Ping Ye, Xiaoqin Xin
Calcium plays a crucial role in many bio-homeostasis functions, such as nerve conduction, coagulation factor regulation, activating enzymes, regulating blood pressure, hormone regulation and contracting muscle. Calcium in the diet is obtained mainly from dairy products. The daily dietary intake of calcium is approximately 800 mg/day in Americans, which is below the recommended dietary allowance (RDA) of 1000–1200 mg/day in adults. Data from a review indicate that adolescents and the elderly are at risk of insufficient calcium intake [9]. Previous studies have shown that calcium had both beneficial and adverse effects on health. A multi-provincial cohort study indicated that high serum calcium may decrease the risk of retinopathy among participants without diabetes [10]. On contrary, growing data from prospective studies pointed out high serum calcium was associated with cardiovascular and metabolic disease risk [11,12]. However, studies exploring the association between calcium and anaemia risk are limited. The study aimed to evaluate the association between serum calcium levels and anaemia prevalence in American adults.
An update on phosphate binders for the treatment of hyperphosphatemia in chronic kidney disease patients on dialysis: a review of safety profiles
Published in Expert Opinion on Drug Safety, 2022
Hiroaki Ogata, Akiko Takeshima, Hidetoshi Ito
A meta-analysis of ten RCTs and quasi-RCTs comparing clinical effects related to hyperphosphatemia among dialysis patients treated with calcium carbonate and calcium acetate demonstrated that calcium acetate significantly decreased serum phosphate levels with a higher incidence rate of intolerance as compared with calcium carbonate [23]. Serum Ca levels were similar in both calcium-based P binders. In addition, no significant difference in all-cause death or cardiovascular events between the two P binders was observed. The main adverse events of calcium carbonate and calcium acetate were gastrointestinal symptoms, including epigastric discomfort/pain, nausea, and poor appetite. The incidences of these events were higher in patients treated with calcium carbonate, which may lead to a higher intolerance to calcium carbonate treatment.
Immunomodulatory properties of antihypertensive drugs and digitalis glycosides
Published in Expert Review of Cardiovascular Therapy, 2022
Paweł Bryniarski, Katarzyna Nazimek, Janusz Marcinkiewicz
Calcium channel blockers reduce the entry of calcium ions into muscle cells. Drugs from this class are divided into two subgroups. Both of these subgroups influence the arteries, relaxing them. Non-dihydropyridine derivatives (diltiazem, verapamil) affect the heart, slowing the frequency of its contractions and reducing its contractility. In contrast, dihydropyridine derivatives (nitrendipine, isradipine, nifedipine, amlodipine, lacidipine, and felodipine) do not have such effects. Indications for the use of calcium channel blockers are coronary artery disease (especially Prinzmetal’s angina), hypertension and arrhythmias (verapamil and diltiazem). The most important contraindications to the use of verapamil and diltiazem are symptomatic bradycardia, sick sinus syndrome, atrioventricular block, Wolf-Parkinson-White syndrome, too low blood pressure (hypotension) and heart failure. In the case of other calcium antagonists, the most important contraindications are severe aortic stenosis, hypertrophic cardiomyopathy with outflow tract obstruction, acute coronary syndrome, hypotension and heart failure. Side effects of calcium antagonists are swelling (mainly of the feet and shins), headache, facial flushing, constipation, slow heart rate, hypotension, and rash.