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Apiaceae Plants Growing in the East
Published in Mahendra Rai, Shandesh Bhattarai, Chistiane M. Feitosa, Ethnopharmacology of Wild Plants, 2021
Sherweit El-Ahmady, Nehal Ibrahim, Nermeen Farag, Sara Gabr
Ammi visnaga L. (Visnaga daucoides Gaertn), commonly known as the toothpick plant and “khella or khella baladi” in Arabic, is a short annual or biennial plant indigenous to the Mediterranean region of North Africa, Asia, and Europe (Chevalier 1996). Ammi majus L. is indigenous to Egypt growing in the Nile Valley, but is also found in some Mediterranean countries, West Africa and parts of Iran. It is commonly known as Bishop’s weed and “khella shaitani” in Arabic. Even though these herbs are the lesser known members of family Apiaceae, nevertheless, their medicinal properties that go back to ancient times make them appreciated wonders of this plant family.
UVA Therapy in Vitiligo
Published in Vineet Relhan, Vijay Kumar Garg, Sneha Ghunawat, Khushbu Mahajan, Comprehensive Textbook on Vitiligo, 2020
Surabhi Dayal, Priyadarshini Sahu
Photochemotherapy use was resumed in 1947, when the active ingredients of Ammi majus, 8-methoxypsoralen (8-MOP) and 5-methoxypsoralen (5-MOP), were isolated. The first trials with 8-MOP and sun exposure were performed in vitiligo patients by El-Mofty in Egypt in 1947. Various publications by Parrish, Fitzpatrick, Tanenbaum, and Pathak reported the beneficial effect of this new type of UVA tube in combination with oral 8-MOP in the treatment of psoriasis. The use of psoralen baths and subsequent UVA exposure (bath PUVA) originated in Scandinavia and is still in use, as it avoids 8-MOP side effects such as nausea and dizziness. However, topical and bath PUVA did not gain as much popularity as the oral form. Hence, photochemotherapy revolutionized dermatological management and in fact was the driving force for a whole new series of discoveries during the next two decades, such as narrowband UVB (NB-UVB), and later UVA1 (340–400 nm) [2].
Historical review of vitiligo
Published in Electra Nicolaidou, Clio Dessinioti, Andreas D. Katsambas, Hypopigmentation, 2019
Maja Kovacevic, Nika Franceschi, Mirna Situm, Andy Goren, Andrija Stanimirović, Yan Valle, Torello Lotti
Seeds of the plant Ammi majus that grows as a weed in the Nile Delta were used by Egyptians. The Arabic pharmaceutical encyclopedia Mofradat Al Adwiya (The Book of Medicinal and Nutritional Terms) written by Ibn El-Bitar (c. 1200 bc) first documented the use of Ammi majus. Exposure to sunlight followed the administration of the remedy. The usefulness of this plant was also known to a Berberian tribe living in northwestern Africa under the name Aatrillal.6,17
Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in rats via suppressing oxidative stress and apoptosis
Published in Biomarkers, 2022
Howaida I. Abd-Alla, Ghadha Ibrahim Fouad, Kawkab A. Ahmed, Kamel Shaker
Phytochemicals are a group of non-nutrient bioactive compounds, widely found in many medicinal plants. Phytochemicals are often used to protect against the development of chronic disorders (Schrader et al. 2018; Abd-Alla et al. 2021). Phytochemicals have been reported as potential therapeutic agents in the management of gastric ulcers and drug-induced hepatorenal toxicity (Mohamed et al. 2014; Adzu et al. 2015; Fahmi et al. 2019a, 2019b). Recently, there is a growing interest in using phytochemicals as complementary, or alternative therapeutic options for the management of gastric ulcers and drug-induced hepatorenal toxicity (Adzu et al. 2015; Abd-Alla et al. 2016, 2021; Aziz et al. 2022). Phenolics such as coumarins which are “benzo-α-pyrones” represent a diverse class of phytochemicals that have attracted a lot of interest due to their anti-oxidative and anti-inflammatory, mucoprotective activities, as well as, their safety in the matter of toxicity in biological systems (Küpeli Akkol et al. 2020; Aziz et al. 2022). Different types of coumarins “simple, furano- and pyran-coumarins” were successfully isolated from Ammi majus (Banikazemi et al. 2021). Ammi majus, commonly called false bishop’s weed, bishop’s flower, bullwort, laceflower, etc., is a member of the carrot family Apiaceae. Herein, we report the isolation and characterisation of eight furanocoumarins from Ammi majus. According to the basic structure, coumarin can be divided into five classes: simple coumarins, furocoumarins, isocoumarins, dicoumarins, and pyranocoumarins. All these classes were isolated from A. majus Linn, which may be regarded as the richest known source of coumarins (Hossain and Al Touby 2020). In this paper we reported the isolation and structure characterisation of eight linear furanocoumarins. Few studies have shed light on coumarins and their gastroprotective potential (Hossain and Al Touby 2020; Banikazemi et al. 2021).
Himalayan poisonous plants for traditional healings and protection from viral attack: a comprehensive review
Published in Toxin Reviews, 2022
Shriya Pathania, Diksha Pathania, Priyanka Chauhan, Mamta Sharma
Berloque dermatitis, triggered by perfumes containing bergamot oil, is a known state in dermatology. There is generally residual pigmentation. Phytoconstituents such as 8-methoxypsoralen and similar furano-coumarins from Ammi majus known as psoralens are photodynamic substances. They absorb UV light, become activated, and then cause cell damage by inhibiting DNA synthesis. These are used in PUVA therapy of psoriasis as psoralens with Ultraviolet A (Wink 2000).