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Anti-Hyperglycemic Property Of Medicinal Plants
Published in Amit Baran Sharangi, K. V. Peter, Medicinal Plants, 2023
Karanpreet Singh Bhatia, Arpita Roy, Navneeta Bhardavaj
Achillea millefolium with a vernacular name Yarrow, is included in Asteraceae family, is endemic to mild temperature zones of Northern Hemisphere in Europe, Asia, and North America and has been brought in New Zealand and Australia as an animal feed. It has been shown to have an anti-hyperglycemic activity by down regulating IL-1β and inducible nitric oxide synthase (iNOS) gene in β cells in STZ-I hyperglycemic rats. Expression level of iNOS and IL-1β was screened and found that the expression level in diabetic rat was significantly ameliorated after treatment with A. millefolium extract (Zolghadri et al., 2014). Hydro alcoholic extract of A. millefolium was tested on normoglycemic and insulin independent diabetic mice model to analyze the anti-diabetic effect and its potential mode of action. It was reported that hydroalcoholic extract ameliorated glucose levels and promoted inhibition of alpha-glucosidase enzyme by 55% at 0.001 g/ml with respect to control, increased PPAR gamma (fivefold) and GLUT4 (two-fold) expression level and also increased secretion of insulin and Ca++ ions in comparison with control exhibits multitarget mode of action (Chávez-Silva et al., 2017).
Psycho-Immunomodulatory Benefits of Aromatherapy
Published in Mehwish Iqbal, Complementary and Alternative Medicinal Approaches for Enhancing Immunity, 2023
It has been observed that the essential oil of Allium sativum and a number of its organosulfur compounds enhanced efficient responses in segregated human neutrophils, resulting in enhanced production of ROS and calcium flux (Schepetkin et al., 2019). Essential oil of Boswellia carterii revealed a powerful immunomodulatory effect when established on lymphocyte multiplying assay. The peripheral venous lymphocytes were activated by the plant lectin (phytohaemagglutinin) in humans, and the mitogenic response brought about by the existence of frankincense essential oil was similar to that of recognised immunostimulants like levamisole and water-based extract of Echinacea purpurea (Mikhaeil et al., 2003). This activation was combined with the manifestation of genes entailed in the production of reactive oxygen species. Correspondingly, the management with essential oil suppressed the most important pro-inflammatory cytokines, interleukin-6 and interleukin-1, putting forth an anti-inflammatory outcome. In one of the studies conducted by Giovannini, the essential oil of Lavandula escalated the innate response of the immune system by activating the process of phagocytosis (Giovannini et al., 2016); it also lessened a subsequent inflammatory reaction hence supporting and harmonising the general immune response. Achillea millefolium (yarrow) is a fragrant herb utilised in alternative medicine, and its indispensable oil is utilised in aromatherapy (Peterfalvi et al., 2019).
Sources of Essential Oils
Published in K. Hüsnü Can Başer, Gerhard Buchbauer, Handbook of Essential Oils, 2020
Chlodwig Franz, Johannes Novak
The genus Achillea is widely distributed over the northern hemisphere and consists of approximately 120 species, of which the Achillea millefolium aggregate (yarrow) represents a polyploid complex of allogamous perennials (Saukel and Länger, 1992; Vetter and Franz, 1996). The different taxa of the recent classification (minor species and subspecies) are morphologically and chemically to a certain extent distinct and only the diploid taxa Achillea asplenifolia and A. roseoalba as well as the tetraploids A. collina and Achillea ceretanica are characterized by proazulens, for example, achillicin, whereas the other taxa, especially 6× and 8×, contain eudesmanolides, longipinenes, germacranolides, and/or guajanolid peroxides (Table 3.4). The intraspecific variation in the proazulene content ranged from traces up to 80%; other essential oil components of the azulenogenic species are, for example, α- and β-pinene, borneol, camphor, sabinene, or caryophyllene (Kastner et al., 1992). The frequency distribution of proazulene individuals among two populations is shown in Figure 3.4.
Antinociceptive synergistic interaction between Achillea millefolium and Origanum vulgare L. extract encapsulated in liposome in rat
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Farshad Hassanzadeh-kiabi, Babak Negahdari
Achillea millefolium (Asteraceae), popularly known by Anador® or Novalgina® (sodium dipyrone) and Atroveran® (sodium dipyrone, papaverine hydrochloride, and Atropa belladonna) with respect to the Brazilian region [4], is a perennial herb that had been used for centuries in folk medicine in different countries. Teas from the aerial parts of the plant are widely used for treating spasms [5], digestive complaints, pain, and other ailments [6]. Literature shows the presence of phytochemicals such as terpenoids, lactones, sesquiterpene essential oils [7,8], flavonoids di-O-glycosides, di-C-glycosides, flavonoid aglycones, and two caffeic acid derivatives, 3,5-dicaffeoylquinic acid and chlorogenic acid [9,10] in A. millefolium. The alkaloid achilleine was found in this specie.
Lethality and effects on biological and population growth parameters of ladybird predator Hippodamia variegata (Goeze) treated by some plant essential oils
Published in Toxin Reviews, 2023
Saeed Shaltoki, Hooshang Rafiee Dastjerdi, Ali Golizadeh, Mahdi Hassanpour, Asgar Ebadollahi, Vahid Mahdavi
Despite being many documents regarding the high potential of essential oils in the management of insect pests, no published information is available regarding the fumigant toxicity and sublethal effects of Achillea millefolium L., Heracleum persicum Desf, and Mentha pulegium L. against H. variegata. The main aim of the current research was to investigate the lethal and sublethal effects of essential oils extracted from A. millefolium, H. persicum, and M. pulegium against H. variegata for determining the possible compatibility of these botanicals and ladybird predator application in IPM strategies.
Effects of Achillea millefolium on cisplatin induced ocular toxicity: an experimental study
Published in Cutaneous and Ocular Toxicology, 2021
Ufuk Okkay, Irmak Ferah Okkay, Ismail Cagri Aydin, Cemil Bayram, Muhammed Sait Ertugrul, Arzu Gezer, Ahmet Hacimuftuoglu
Achillea Millefolium purchased from Herb Pharm (Oregon, USA) as hydroalcoholic extract prepared by treating the dried flowering parts of the plant with a solvent (68–58% organic cane alcohol) in the ratio of 1: 5 (v/v). Cisplatin (50 mg/100 mL Cisplatin®) was purchased from Koçak Farma (Turkey).