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Atlas of Autofluorescence in Plant Pharmaceutical Materials
Published in Victoria Vladimirovna Roshchina, Fluorescence of Living Plant Cells for Phytomedicine Preparations, 2020
Victoria Vladimirovna Roshchina
Wild camomile or chamomile (Matricaria chamomilla L.), a well-known medicinal plant species from the Asteraceae family, is an example of predominant characteristic components in pharmaceutical material (Franke and Schilcher 2005; Murav’eva et al. 2007). Nowadays, it is a highly favored and much used medicinal plant in folk and traditional medicine (Duke 2002; Murav’eva et al. 2007; Singh et al. 2011) due to specific aroma components that are constituents of the essential oil from leaves and flowers. The plant species has multitherapeutic, cosmetic, and nutritional values. It is often used as a natural anti-inflammatory, antibacterial, and spasmolytic drug (Murav’eva et al. 2007; Singh et al. 2011). Moreover, the chamomile azulenes and proazulenes found in the essential oil have demonstrated antiallergic features (Singh et al. 2011). Some phenols and monoterpenes are included in the emission, but in a smaller degree in the glands and mainly concentrated in secretory hairs (Murav’eva et al. 2007; Singh et al. 2011).
The Anticancer Effect of Inula viscosa Methanol Extract by miRNAs’ Re-regulation: An in vitro Study on Human Malignant Melanoma Cells
Published in Nutrition and Cancer, 2022
Dilara Kamer Colak, Unal Egeli, Isil Ezgi Eryilmaz, Onder Aybastier, Hulusi Malyer, Gulsah Cecener, Berrin Tunca
Turkey’s natural resources offer scientists a comprehensive catalog for research on new therapeutic agents in cancer therapy. One of these, Inula viscosa (L.) Aiton (IV, “sticky fleabane”, “yapışkan andız otu” in Turkish) is a perennial herb that belongs to the genus Inula and the family Asteraceae. It has approximately a hundred species worldwide and is represented by twenty-seven species, including endemics on Turkey’s geographic boundaries (11). In addition to being consumed as a tea, IV has been used in traditional medicine to treat many diseases such as diabetes, hypertension, bronchitis, tuberculosis, wounds, skin diseases, etc. (12–18). Studies on IV showed that it has consisted of many pharmacologically active compounds, including terpenes, flavonoids, anthranilic acids, lactones, guaianolides, azulenes, costic acid, and essential oils that enable the herb to have a large number of biological activities (19). The presence of antiproliferative, cytotoxic, and anticancer effects due to these components revealed the necessity of IV to be considered as research material for cancer therapy. A few studies in the literature investigate the anticancer effect of IV from different geographical regions in some cancer types (20–27). The results of these studies may vary depending on the cells given and the solvent in which the extract is prepared. Besides, no study evaluated any IV extracts’ effects on metastatic MM, except two of IV’s components (24).
Insights into the potential mechanism underlying liver dysfunction in male albino rat exposed to gasoline fumes
Published in Egyptian Journal of Basic and Applied Sciences, 2021
Folarin Owagboriaye, Sulaimon Aina, Rasheed Oladunjoye, Titilola Salisu, Adedamola Adenekan, Gabriel Dedeke
A total of 23 hydrocarbon components were detected in the gasoline used for this study (Supplementary Table S1). Toluene has the highest percentage composition in the gasoline sample. This was followed by o-xylene, naphthalene, undecane, ethylbenzene and p-Xylene. A total of seventeen (17) hydrocarbon components, including gasoline metabolites, were detected in the liver of the experimental rats (Table 3). Benzene was detected in the liver of rats in all the groups. However, benzene level was significantly reduced in group I. Paracyclophane and ethylbenzene were only detected in the liver of rats in group III. Similarly, 4,7-Methano-1 H-indene, Azulene, Cyclobutane, 3-Phenylthiane, Quinoline and 1-benzylindole were only detected in the liver of rats in group V.
Seasonal Variation of Phyto-Constituents of Tea Leaves Affects Antiproliferative Potential
Published in Journal of the American College of Nutrition, 2019
Sayantan Maitra, Arnab De, Bhaskar Das, Sudipendra Nath Roy, Ranadhir Chakraborty, Amalesh Samanta, Subhrajit Bhattacharya
Preliminary phytochemical analysis has revealed the presence of nearly all commonly tested phytoconstituents in both MECR and MECA except triterpenoids and sesquiterpenes, which were present exclusively in MECR as shown in Table 1. The total flavonoid content in MECR and MECA was found to be 95 ± 3.9 mg and 90.1 ± 6.3 mg quercetin equivalent/g of each of the extract powders, respectively, in reference to the standard curve. Gas chromatography–mass spectroscopy (GC-MS) data enabled identification of the biochemicals present in MECR and MECA samples (Table 2). Both the samples showed a conspicuous peak (near retention time of 20 min) corresponding to caffeine (Figure 1(a) and (b)). Three peaks, corresponding to the presence of hexadecanoic acid methyl ester at 23 min, cyclobarbital at nearly 25 min, and benz[e]azulene derivative near 30 minutes, were present in MECR (Figure 1(a)) but absent in MECA (Figure 1(b)). The presence of additional phytochemicals in MECR may have contributed to increased antitumorigenic activity in comparison to MECA.