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Surgical Techniques: Subcision, Grafting, Excision, and Punch Techniques
Published in Antonella Tosti, Maria Pia De Padova, Gabriella Fabbrocini, Kenneth R. Beer, Acne Scars, 2018
Rohit Kakar, Farhaad Riyaz, Megan Pirigyi, Murad Alam
To perform punch elevation, a punch instrument is chosen that exactly matches the diameter of the scar base (Figure 12.4). The punch is inserted down to the level of subcutaneous fat so that the tissue may be manipulated [48]. Next, forceps are used to gently elevate the scar base until it sits slightly higher than the surrounding surface, and the tissue is held in place for 1 or 2 minutes until a coagulum forms beneath it [48] (Figure 12.4). The plug is then secured in place using sutures, Dermabond (2-octyl cyanoacrylate, Ethicon, Inc., Somerville, NJ, USA), or Steri-Strips [19]. The area is covered with a topical antibiotic and dressed with gauze, and the patient is instructed to gently wash the area and reapply a topical antibiotic twice a day [1].
Pharmacology for venous and lymphatic diseases
Published in Ken Myers, Paul Hannah, Marcus Cremonese, Lourens Bester, Phil Bekhor, Attilio Cavezzi, Marianne de Maeseneer, Greg Goodman, David Jenkins, Herman Lee, Adrian Lim, David Mitchell, Nick Morrison, Andrew Nicolaides, Hugo Partsch, Tony Penington, Neil Piller, Stefania Roberts, Greg Seeley, Paul Thibault, Steve Yelland, Manual of Venous and Lymphatic Diseases, 2017
Ken Myers, Paul Hannah, Marcus Cremonese, Lourens Bester, Phil Bekhor, Attilio Cavezzi, Marianne de Maeseneer, Greg Goodman, David Jenkins, Herman Lee, Adrian Lim, David Mitchell, Nick Morrison, Andrew Nicolaides, Hugo Partsch, Tony Penington, Neil Piller, Stefania Roberts, Greg Seeley, Paul Thibault, Steve Yelland
The cyanoacrylate molecule has a two-carbon ethylene group, a B-carbon which has two hydrogens attached which contribute to its electric activity, and an A-carbon which has a cyano-group and an ester function called a carbonyl (Figure 5.5a). Various hydrocarbons perform the carbonyl function and provide its name, such as n-butyl cyanoacr ylate, ethyl2-cyanoacrylate, methyl 2-cyanoacrylate and 2-octyl cyanoacrylate.
Skin hypersensitivity following application of tissue adhesive (2-octyl cyanoacrylate)
Published in Baylor University Medical Center Proceedings, 2021
Raymond P. Shupak, Sid Blackmore, Roderick Y. Kim
Skin adhesives are frequently used for wound closure. Advantages include added strength to wound closure, microbial barrier protection, and patient comfort, convenience, and cosmesis.1–3 One common skin adhesive available for use is 2-octyl cyanoacrylate (DermabondTM). Dermabond is indicated for closely approximated surgical skin wounds and cleansed traumatic lacerations.4 It is contraindicated in areas of infection and in mucosal surfaces/junctions of skin and mucosa, as well as in patients with a hypersensitivity to cyanoacrylate, formaldehyde, or benzalkonium.4 Typically, skin adhesives are generally very well tolerated; however, there have been rare reports of adverse reactions. Infection, hypersensitivity reactions, wound dehiscence, pruritus, and skin blistering are potential adverse side effects of its use. Skin reactions can present immediately or in a delayed fashion.5 This report describes two incidents of allergic hypersensitivity reaction to skin adhesive following topical application in head and neck surgery.
The Adjunctive Effect of DuraSeal® vs. 2-Octyl-Cyanoacrylate on Delayed Repair of Gastric Perforation: An Experimental Study
Published in Journal of Investigative Surgery, 2022
Fatih Akgunduz, Alper Sozutek, Oktay Irkorucu, Abit Yaman
In fact, adhesive materials such as fibrin glue and acrylate derivatives are currently used as a primary or adjunctive treatment of many surgical complications including embolization, bleeding, GI fistula and perforation [10,12–18]. Because of its clinically proven efficacy and strength, cyanoacrylate is commonly preferred than fibrin glue in clinical practice. It works by polymerizing reaction; it creates a forcible bond between the tissues followed by applying to a moist area [19]. Since 2-Octyl-Cyanoacrylate is the most strength one, we preferred to compare it in this study.
Sealing clear corneal incisions in cataract surgery
Published in Expert Review of Ophthalmology, 2018
Manpreet Kaur, Ankit Tomar, Farin Shaikh, Ruchita Falera, Lalit M. S. Bageshwar, Jeewan S. Titiyal
Meskin et al. observed water-tight wound closure in 100% of eyes after the application of 2-octyl cyanoacrylate to seal the CCIs [59]. The adhesive either partially or completely dislodged in 12% patients on postoperative day 1, but the wound stability was not affected. However, 61% patients complained of postoperative foreign body sensation and 51% patients had diffuse bulbar conjunctival hyperemia.