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Diarrhea (Acute)
Published in Charles Theisler, Adjuvant Medical Care, 2023
Oral rehydration solutions (Pedialyte) can be used for moderately severe diarrhea that is accompanied by dehydration in children older than 10 years of age and in adults. These solutions are given at 50 ml/kg over 4–6 hours for mild dehydration or 100 ml/kg over 6 hours for moderate dehydration.10
Parenteral and Enteral Nutrition in Critical Illness
Published in Michael M. Rothkopf, Jennifer C. Johnson, Optimizing Metabolic Status for the Hospitalized Patient, 2023
Michael M. Rothkopf, Jennifer C. Johnson
I have also seen ½ or even ¼ strength vivonex used as an ORT for the hospitalized malnourished patient. This has the advantage of containing a small amount of amino acids and medium-chain triglycerides. But even this dilute formula may be too much for some. In those cases, you can revert to the D5 ½ NSS/K citrate format. I should also mention the option of using Pedialyte™ either full strength or diluted for this role.
College students’ experiences with substance use at electronic music events: A qualitative study
Published in Journal of American College Health, 2023
Ashley Falcon, Valerie A. Halstead, Brian E. McCabe
Participants discussed several common day-of protective measures before taking substances. These included staying hydrated (e.g., drinking water/Pedialyte/Gatorade, using water backpacks), staying nourished (e.g., eating beforehand, preparing snacks), and staying with a group (e.g., conducting head counts, identifying a meeting point if lost, having a safety plan exit strategy). In addition to day-of measures, other protective measures were identified that could be done before/leading up to the planned substance use. These included weighing/testing drugs, researching appropriate dosage, and understanding the effects of substances. Some participants expressed the importance of guidance from an experienced user, especially if trying substances for the first time. However, other participants cautioned that it is important to not blindly rely on someone else’s opinion. For example, one participant stated,
Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect
Published in Gut Microbes, 2022
Archana Kini, Bei Zhao, Marijana Basic, Urmi Roy, Aida Iljazovic, Ivan Odak, Zhenghao Ye, Brigitte Riederer, Gabriella Di Stefano, Dorothee Römermann, Christian Koenecke, André Bleich, Till Strowig, Ursula Seidler
slc26a3−/− mice26 were bred and maintained at Hannover Medical School under standard temperature and light conditions, as previously described8 and were allowed free access to food and a half maximal Pedialyte drinking solution to prevent dehydration and enable increased survival post weaning. All mice in the experiments were age matched and used between 4 and 20 weeks of age. The wild-type and knockout littermates were co-housed from birth and monitored daily. Four-week-old male and female germ-free C57BL/6 J mice were housed in static micro-isolators (gnotocages) with autoclaved food, water and bedding at the Hannover Medical School. All experiments involving animals were approved by the Hannover Medical School committee on investigations involving animals and an independent committee assembled by the local authorities (Authorization number: 33.14–42502-04-14/1549 and 33.19–42502-04-20/3561).
Evaluation of the Macy Catheter®: a rectal catheter for rapid medication and fluid administration
Published in Expert Review of Medical Devices, 2018
Kim Marie C. Macygin, Erik Kulstad, Robert K. Mokszycki, Morgan Goldsmith
Cost comparison of the Macy Catheter with other more commonly used fluid and medication delivery routes is challenging. Each published cost analysis of fluid and medication delivery systems combines different varied factors to total cost: the device itself, additional physical supplies, labor time, and cost of labor/level of the provider to initiate. Additionally, when considering the cost of any fluid or medication delivery system, it may be prudent to consider the frequency at which the device will need to be reinserted or changed, the potential for and cost of complications, as well as the cost of the fluid or medication administered via that route. Table 1 lists several of these factors for comparison. The Macy Catheter may provide a more cost-effective fluid and medication route for both acute and post-acute care patients when one considers that the Macy Catheter can be placed quickly by any trained healthcare provider into a non-sterile, natural orifice; it can be left in place up to 28 days and complications are unlikely. Either sterile or non-sterile fluids, such as water or Pedialyte®, have been used for rehydration, and the medications to be administered are pills crushed and administered via microenema. All of these considerations suggest the Macy Catheter is a lower-cost intervention for medication and fluid delivery. As the Macy Catheter matures in the market, more data for cost analysis should become available.