China
Africa
Explore chapters and articles related to this topic
Non-Neoplastic Salivary Gland Diseases
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Stephen R. Porter, Stefano Fedele, Valeria Mercadante
Necrotizing sialometaplasia is an uncommon disorder that typically affects the minor salivary glands of the palate, although may rarely involve other minor salivary glands and, very unusually, the major salivary glands.322 It presents typically as a palatal swelling that breaks down to give rise to localized, irregular ulceration.
The mouth, tongue and lips
Published in Kevin G Burnand, John Black, Steven A Corbett, William EG Thomas, Norman L Browse, Browse’s Introduction to the Symptoms & Signs of Surgical Disease, 2014
Kevin G Burnand, John Black, Steven A Corbett, William EG Thomas, Norman L Browse
Necrotizing sialometaplasia is a benign, inflammatory condition that mostly affects the minor palatal salivary glands. It usually occurs in young male smokers. It presents as irregular ulcers in the area of the junction between the hard and soft palates (Fig. 11.36). It is almost indistinguishable from a cancer except by biopsy. The condition is self-limiting.
Oral manifestations of extranodal lymphomas – a review of the literature with emphasis on clinical implications for the practicing dentist
Published in Acta Odontologica Scandinavica, 2022
Malin Höglund Wetter, Ulf Mattsson
Eighty-seven cases (49 men and 39 women) with a mean age of 56.7 years (SD 20.0) described isolated involvement of the palatal mucosa. The time from debut of symptoms to clinical examination/diagnosis was given in 39 cases with a mean value of 3.2 months (SD 2.9). Subjective symptoms mainly consisted of an awareness of a swelling or ulceration, but the lesions were not necessarily associated with pain, which was only described in 16% of the cases (Table 4a). Several of the symptoms described in Table 4a could likely be attributed to involvement of the nasal cavity or extension into the soft palate. Eight patients had no subjective symptoms at all. The clinical size was given or could be estimated in 62 cases. Twenty-five cases (40%) had a largest diameter exceeding 3 cm, suggesting that lymphoma in the palate can also grow rapidly. A tentative diagnosis was given in 29 cases and the most common were infection/stomatitis or necrotizing sialometaplasia (n = 13). Squamous cell carcinoma was suspected in three and salivary gland tumour in four cases. A tentative diagnosis of lymphoma was only given in two cases.
Salivary myoepithelial cells: an addendum
Published in Ultrastructural Pathology, 2018
Asterios Triantafyllou, Lauge Hjorth Mikkelsen, Douglas R. Gnepp, Simon Andreasen, Jennifer L. Hunt, Kenneth O. Devaney, Vincent Vander Poorten, Alessandra Rinaldo, Stefan M. Willems, Alfio Ferlito
An electron-microscopical investigation reported a possible example of metaplasia of myoepithelial cells of rat submandibular and sublingual glands following ligation of the feeding artery.53 The ischemic alterations included the appearance of cytoplasmic tonofilament bundles firstly in luminal epithelial cells and later in cells at the periphery of the parenchyma. The authors interpreted the peripheral cells as myoepithelia undergoing squamous metaplasia.53 Immunoelectron microcopy for actin was not performed. The late involvement of myoepithelium in squamous metaplasia accords with the common presence of calponin- or SMA-positive myoepithelial cells surrounding the squamoid epithelial islands in necrotizing sialometaplasia.54