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Benign Neck Disease
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Ricard Simo, Jean-Pierre Jeannon, Enyinnaya Ofo
Kikuchi disease (KD) is a self-limiting disease of lymph nodes that usually affects young women. It is also known as Kikuchi-Fujimoto disease and was first described by Kikuchi from Japan in 1972.96, 97 Histologically, it is characterized by a histiocytic necrotizing lymphadenitis.
Case 87: Fevers, Night Sweats and Lymphadenopathy
Published in Layne Kerry, Janice Rymer, 100 Diagnostic Dilemmas in Clinical Medicine, 2017
Kikuchi disease, otherwise known as histiocytic necrotising lymphadenitis, is a condition that primarily affects young adults of Asian ethnicity, particularly Japanese people. Symptoms and signs can be difficult to distinguish from lymphoma or tuberculosis, or systemic lupus erythematosus in some cases, with the diagnosis often only being established once histopathology results are available. Treatment is typically supportive, although corticosteroids may be warranted in patients with moderate symptoms. Immunosuppressant agents may be required in severe cases.
Kikuchi disease as a possible cause of ischaemic stroke: a case report
Published in International Journal of Neuroscience, 2021
Lihui Liu, XingLi Tan, Yunhai Liu, Ziyuan Liu, Jie Yang, Qing Huang
Kikuchi disease, also known as Kikuchi-Fujimoto disease (KFD) or histiocyte necrotizing lymphadenitis, is a rare and self-limiting benign disease which was first described by Kikuchi and Fujimoto in 1972 [1,2]. It usually occurs in young women and is characterized by lymphadenopathy of the cervical lymph nodes and nonspecific systemic symptoms, such as fever [3]. For Kikuchi disease, the reported neurological complications occur in about 11% of cases as revealed by a review of 244 cases [4], including aseptic meningitis, encephalitis, mononeuritis multiplex, brachial neuritis, peripheral neuropathy and photophobia [5,6]. To date, transient ischaemic attacks (TIA) following KFD has not been reported. TIA is a cerebrovascular disease condition involving transient, localized impairment of brain function and, is usually a forerunner for ischemic stroke, which is a leading cause of death and disability. Herein, an unusual case about KFD co-existence with TIA was presented for discussion.