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Smallpox
Published in Scott M. Jackson, Skin Disease and the History of Dermatology, 2023
The oral smallpox vesicles and pustules erode, exposing the deeper layers of the oral cavity, resulting in extreme discomfort with eating or talking. Starvation-induced weight loss is not uncommon. Cadaveric facies, wasted appearance, and loss of muscle strength and tone are typical. Blindness as a consequence of blistering of the ocular surface is not uncommon. The patient emits a fetor, which has been described as “oppressive” and “the sweetish, pungent smell of rotting flesh.”1
Gastroenterology
Published in Kaji Sritharan, Jonathan Rohrer, Alexandra C Rankin, Sachi Sivananthan, Essential Notes for Medical and Surgical Finals, 2021
Kaji Sritharan, Jonathan Rohrer, Alexandra C Rankin, Sachi Sivananthan
Diverticulum of the pharyngeal muscosa through a weakness in the wall between the thryopharyngeus and cricopharyngeus. Presentation: typically with abnormal fetor and dysphagia or complications such as aspiration. Diagnosis is confirmed with barium swallow. Management: pouch can be excised surgically if problematic.
ENT Emergencies
Published in Anthony FT Brown, Michael D Cadogan, Emergency Medicine, 2020
Anthony FT Brown, Michael D Cadogan
There is fever, fetor, sore throat and dysphagia. A febrile convulsion may be precipitated in a child <5 years old.
Breathing new life into clinical testing and diagnostics: perspectives on volatile biomarkers from breath
Published in Critical Reviews in Clinical Laboratory Sciences, 2022
Jordan J. Haworth, Charlotte K. Pitcher, Giuseppe Ferrandino, Anthony R. Hobson, Kirk L. Pappan, Jonathan L. D. Lawson
Metabolic alterations, associated with CLD, modify the profile of circulating metabolites [74] as a result of changes in hepatic gene expression [75–78], enzyme activity [79–84], and liver extraction capacity due to portosystemic shunting and sinusoidal capillarization [85,86]. Routes of excretion for a subset of these metabolites include exhaled breath [87]. Therefore, breath metabolomic analysis represents an attractive means for the identification of biomarkers associated with CLD that are suitable for a noninvasive test. The principle of breath testing was understood by Hippocrates (460–370 BC), who described fetor hepaticus, mentioned previously [88]. More recently, GC techniques have been used to identify dimethyl sulfide as the main breath compound responsible for fetor hepaticus [21,89–91].
Incidence of alveolar osteitis after mandibular third molar surgery. Can inflammatory cytokines be identified locally?
Published in Acta Odontologica Scandinavica, 2021
Hauk Øyri, Janicke L. Jensen, Pål Barkvoll, Olga H. Jonsdottir, Janne Reseland, Tore Bjørnland
The study was designed as a prospective controlled study. The study population comprised all patients having third molar surgery, during the period 1 January to 31 December 2014. Patients diagnosed with AO within one week after third molar surgery were selected for further examination. A control group, which had undergone third molar surgery without developing AO, was consecutively recruited during 2015 and 2016. The regional ethical committee for medical research (REK) approved the study (2013/2382 REK sør-øst). Patients were given written information about the study when presenting at the Department of Oral Surgery and Oral Medicine (DOS) with symptoms of AO within the first week after surgery. Those willing to participate in the study then signed informed consent forms. Inclusion criteria were age ≥18 years, symptoms and clinical findings according to the presence of AO and no previous treatment for AO. Diagnostic criteria for AO were defined as strong postoperative pain radiating from the surgical site intensified 2–4 days postoperatively, and possibly foetor. Subjective symptoms should correspond with clinical findings of an empty alveolus lacking a blood clot and/or exposed bone [13,14]. Exclusion criteria were age <18 years, postoperative symptoms not defined as AO, failure to present for further follow-up, and initiated treatment for AO.
The first experiences of implementation of the Swedish tonsil register in Denmark
Published in Acta Oto-Laryngologica, 2020
Jannik Buus Bertelsen, Therese Ovesen
All patients undergoing acute or elective tonsillotomy or tonsillectomy with or without simultaneous adenoidectomy were eligible for the register. Exclusion criteria were suspicion of cancer or inability to fulfil questionnaires in Danish. As requested by Danish law, written informed consent was obtained from all the patients, or from caregivers of children below 18 years of age prior to the electronic registration of the procedure. Based on EMR, the surgeons noted demographics as age, height, weight, out- or inpatient care, co-morbidity as well as indication for surgery: Airway obstructiveness (hypertrophy), recurrent tonsillitis, peritonsillar abscess, chronic tonsillitis, foetor ex ore/tonsillar stones, systematic complications, or others. After surgery, all data were registered online into the registry (a single page form) by the surgeon including choice of surgical technique (cold knife tonsillectomy, radio frequency unit, thermal welding technique, ultracision, impedance dependant sealing, laser, monopolar diathermy or other techniques). The procedure for haemostasis other than compression was noted (infiltration analgesia containing adrenalin, unipolar diathermy, bipolar diathermy, ligature, suture ligation radio frequency or others). Before discharge, complications during the hospital stay were registered (primary bleeding and it´s treatment: observation or haemostasis in general anaesthesia).