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General Thermography
Published in James Stewart Campbell, M. Nathaniel Mead, Human Medical Thermography, 2023
James Stewart Campbell, M. Nathaniel Mead
Along with viral infections and allergies, chronic sinusitis can be caused by structural abnormalities in the nasal passages, a tumor, or nasal polyp that keeps the sinuses from draining normally.75 Chronic fungal infection of the sinuses can also occur. Thermography is useful to differentiate bacterial sinusitis versus viral or congestive sinus pain. The thermographic appearance of chronic fungal sinusitis and other conditions remains to be studied.
The Head and Neck
Published in E. George Elias, CRC Handbook of Surgical Oncology, 2020
The maxillary sinus has an anterior wall that relates to the cheek and the floor of the orbit; a roof which constitutes the floor of the orbit, the posterior wall is related to the pterygoid fossa; and the base is made of a thin bone which is divided by the insertion of the inferior turbinate. The maxillary sinus communicates with the nasal fossa in the upper half of the base. The lymphatic drain to the submandibular, retropharyngeal, and jugular lymph nodes. Tumors of the sinus include epidermoid carcinoma, gingival tumors invading the sinus, osteosarcoma, Ewing’s sarcoma, chondrosarcoma, Burkitt’s lymphoma, and rarely adenocarcinoma and plasmacytoma. The patients may present early with signs of chronic sinusitis, and later they will have nasal or dental symptoms or even eye displacement. These symptoms should be differentiated from the maxillary sinusitis (as mentioned before), papillary metaplasia, dentigerous cyst, odontomas, mucocele, ameloblastoma, fibro-osteoma invading the bone (cystic or solid), and giant cell tumor of the bone. Bone destruction can be seen on a plain X-ray but more detail can be obtained by a CT scan. A biopsy can be obtained from the maxillary sinus by Caldwell-Luc or nasal fenestration to establish the diagnosis.
Example of the Integrated Management of a Disease: Acute and Chronic Sinusitis
Published in W. John Diamond, The Clinical Practice of Complementary, Alternative, and Western Medicine, 2017
Definition and symptoms — Acute and chronic sinusitis is an inflammation or infection of the paranasal sinuses that causes a feeling of congestion, mucoid or mucopurulent nasal discharge, postnasal drip, cough, local pain, and headache with fatigue and malaise.
Machine learning method for the cellular phenotyping of nasal polyps from multicentre tissue scans
Published in Expert Review of Clinical Immunology, 2023
Jing Ding, Changli Yue, Chengshuo Wang, Wei Liu, Libo Zhang, Bo Chen, Shen Shen, Yingshi Piao, Luo Zhang
Tissue sections were obtained from 67 patients at Tongren Hospital, Beijing, China, between January 2019 and November 2021 and randomly divided (at a 4:1 ratio) into a training (n = 54) and test cohort (n = 13). Tissue sections obtained from 55 patients at external hospitals were used as a validation cohort (Table 1). The criteria for selecting patients are as follows: 1) CRSwNP in line with the diagnostic criteria of ‘Chinese Guidelines for Diagnosis and Treatment of Chronic Sinusitis (2018); 2) CRSwNP have been treated with medication or surgery for nasal polyps; 3) Persistent nasal congestion, reduced/loss of smell, runny nose and other symptoms. Tissue sections were scanned using a NanoZoomer-XR Digital Scanner (Hamamatsu Photonics, Hamamatsu City, Japan) to obtain 122 digital whole-slide images (WSIs). We extracted 6,923 patches were extracted from WSIs under 400× HPF using Openslide software (version 3.4.1; University of Pittsburgh, Pittsburgh, PA, U.S.A). Certain tissues, including enclaves, blood vessels, vessels, and epidermis, were automatically identified and removed by the semantic segmentation algorithm of Unet++ with Efficientnet-B4 as backbone. A total of 4,714 and 935 patches from Tongren Hospital were used for training and testing, respectively, and validation tests were conducted using 1,274 patches from the multicentre dataset.
Documentation of asthma control and severity in pediatrics: analysis of national office-based visits
Published in Journal of Asthma, 2020
Sanika Rege, Abhishek Kavati, Benjamin Ortiz, Giselle Mosnaim, Michael D. Cabana, Kevin Murphy, Rajender R. Aparasu
Very limited data exist regarding the characteristics associated with documentation of asthma severity and control. This study analyzed the patient and physician characteristics associated with the documentation of asthma severity and control, which to the authors’ knowledge has not been done previously. The study found that providers are nearly four times more likely to document asthma control in established versus new patients. The study also found racial variation in the documentation of asthma control; documentation is two times higher among Hispanics than non-Hispanic patients. Providers are more likely to document asthma control in patients with chronic sinusitis. This may be attributed to the impact of chronic sinusitis on asthma symptomatology. The study also found regional variation in the documentation; documentation is two times higher among providers from the Northeast region than those from the West. The likelihood of documentation is significantly lower in those with undocumented asthma severity and in visits in the spring season. This suggests significant correlation between asthma control and severity documentation as providers following national asthma guidelines are likely to document both.
Favorable response to asthma-dosed subcutaneous mepolizumab in eosinophilic pneumonia
Published in Journal of Asthma, 2019
Robert Y. Lin, Toni P. Santiago, Nina M. Patel
A 48-year-old Caucasian female presented in June 2010 with a history of respiratory symptoms since 2007, before which time there was no history of asthma. There was a history of prior cigarette smoking, uterine fibroid surgery, malocclusion jaw surgery, and breast augmentation surgery. She had been treated for recurrent pneumonia, once in 2007 as an outpatient and twice in 2008 when she was hospitalized on two separate occasions and was prescribed prolonged courses of intravenous antibiotics. Patchy bilateral infiltrates with areas of ground glass opacities were reported on a November 2008 chest CT scan. Pulmonary function studies from December 2008 showed normal values for forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC ratio. She was hospitalized for pneumonia again in April 2010, where Pseudomonas infection was documented on bronchoscopically obtained respiratory cultures. Bronchoalveolar lavage examination showed many white blood cells consisting of neutrophils and lymphocytes. The patient was evaluated by an otolaryngologist whose diagnosed chronic sinusitis; CT scan of the paranasal sinuses at that time showed opacification of most of the sinuses.