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Pathology of Breast Cancer
Published in Raymond Taillefer, Iraj Khalkhali, Alan D. Waxman, Hans J. Biersack, Radionuclide Imaging of the Breast, 2021
Tubular carcinoma is a distinct variant of breast carcinoma which constitutes about 20% of nonpalpable breast lesions [103]. It occurs in younger age groups than infiltrating duct cell carcinoma, and is associated with a higher incidence of bilaterality and multiplicity [104]. A family history of breast carcinoma has been found in 40% of patients with tubular carcinoma [105]. Mammographically, tubular carcinoma presents as a small spiculated abnormality or as an early ductal carcinoma [106].
The breasts
Published in C. Simon Herrington, Muir's Textbook of Pathology, 2020
Key Points There is a wide variety of histological sub-types of invasive breast carcinoma, including: Invasive no specific/special type (NST) (previously, and still sometimes, called ductal), is the most common (>50%).Invasive lobular carcinoma (of which there are several variants) is the second most common type (approximately 15%).Tubular carcinoma is more common in screening than symptomatic practice.Mucinous, invasive micropapillary, invasive cribriform, metaplastic, and a variety of other types (including salivary gland-like variants) are all rare.Mixed histological types are not uncommon.
Cancer of the Breast
Published in P. Pertschuk Louis, Lee Sin Hang, Localization of Putative Steroid Receptors, 2018
Pietro Lampertico, Franca Stagni
In the series of 2980 breast cancers assayed biochemically and collected by Underwood,43 ductal carcinomas had a median positivity of 62% (range: 46 to 77%) and lobular carcinomas 80% (range: 49 to 100%). Medullary carcinomas had a mean positivity of 26% (range: 9 to 58%). Thus, there were no significant differences as to positivity between histochemical and biochemical assay results in the more common breast tumors. The relatively uncommon tubular carcinoma was consistently more positive in the current series, while biochemical assay results were more variable.43 Some observers have related high positivity in this tumor to its relatively advanced state of differentiation.35 Pari and Wagner23 reported positivity in 95% of highly differentiated tumors and 79 and 64%, respectively, in those of medium and low grades of differentiation. A similar relationship, also reported by others,44-45 was not sought for in this study.
Case report: acromegaly and breast cancer in a woman with turner syndrome
Published in Gynecological Endocrinology, 2021
Sabine Naessén, Kerstin Landin-Wilhelmsen
Genetics and family history, radiation to the face or chest for treatment of another type of cancer before the age of 30, are known risk factors for tubular carcinoma. There is no family history of breast cancer in this case, but the patient received external radiation against the pituitary 24 years before the breast cancer diagnosis and the radiation was not aimed at the chest. The probability that the breast cancer has arisen due to the radiation to the face/head for treatment of acromegaly should be minimal.
Autophagy in advanced low- and high-grade tubular adenocarcinomas of the stomach: An ultrastructural investigation
Published in Ultrastructural Pathology, 2018
Rosario Alberto Caruso, Giuseppe Angelico, Eleonora Irato, Rosalba de Sarro, Giovanni Tuccari, Antonio Ieni
The clinicopathologic features of the low-grade and high-grade gastric tubular carcinoma cases are summarized in Table 1. Patient age ranged from 55 to 80 years (median 67 years) in the low-grade tubular carcinoma group and from 60 to 86 years (median 55 years) in the high-grade tubular carcinoma group. Low-grade group has eight cases in stage II and four cases in the stage III, while the high-grade group has 11 cases in stage III and two cases in stage IV.