Tonsil carcinoma

Tonsil carcinoma

Transoral Laser Microsurgery

Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018

Mark Sayles, Stephanie L. Koonce, Michael L. Hinni, David G. Grant

When resecting a tonsil carcinoma, following adequate exposure, it is usual to start by transecting the tumour in the axial plane at the mid-point, immediately separating the tumour into a superior and inferior portion.

Cross-comparison of microbiota in the oropharynx, hypopharyngeal squamous cell carcinoma and their adjacent tissues through quantitative microbiome profiling

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Journal Information

Published in Journal of Oral Microbiology, 2022

Hui-Ching Lau, Yujie Shen, Huiying Huang, Xiaohui Yuan, Mengyou Ji, Hongli Gong, Chi-Yao Hsueh, Liang Zhou

In the past five years, the variations in the oral microbiome were shown to have the potential in acting as prognosis predictors in HNC, especially for oral squamous cell carcinoma (OSCC) [12], tonsil carcinoma [13] and laryngeal carcinoma [14]. The application of differential microbiome was also found in several longitudinal therapeutic studies. Here, we conducted a cross-sectional study by collecting up to three distinct samples from each patient with HPSCC: the tissue of the hypopharyngeal carcinoma (HC), their adjacent tissue (AT), and swab sampling on oropharyngeal mucosa (OPM). We wished to answer whether microbiota changes in OPM can be considered as changes in flora structure on the tumor site and whether combined QMP and RMP could benefit in interpreting the variation in these three groups.

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Transoral Laser Microsurgery

Cross-comparison of microbiota in the oropharynx, hypopharyngeal squamous cell carcinoma and their adjacent tissues through quantitative microbiome profiling