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Pericardium
Published in Mary N. Sheppard, Practical Cardiovascular Pathology, 2022
Solitary fibrous tumour is a rare mesenchymal tissue-originating tumour characterized by cells that have fibroblast and/or myofibroblastic differentiation. In contrast to sarcomatoid mesotheliomas, solitary fibrous tumours are composed of relatively bland spindled cells. There is no expression of epithelial markers and the cells are CD34 positive. Some may have cellular areas with pleomorphism and mitotic figures indicating that they are malignant fibrous tumours which may recur and infiltrate surrounding structures.
Tumors of the Nervous System
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
Cerebral convexity: Dural metastasis from carcinoma.Lymphoma.Solitary fibrous tumor.
Malignant Solitary Fibrous Tumor of the Pleura
Published in Wickii T. Vigneswaran, Thoracic Surgery, 2019
Amber Redmond, Eric P. Anderson, Christopher W. Seder, Nicole M. Geissen
Solitary fibrous tumors (SFTs) are rare neoplasms that arise from tissue with mesenchymal origin [1]. Although relatively rare, the number of patients being diagnosed with SFTs is on the rise. While the majority of SFTs arising from the pleura are benign, 13%–23% are classified as malignant [1]. After a complete resection, recurrence of a malignant solitary fibrous tumor (MSFT) has been reported as late as 16 years after initial presentation [2]. Given the unpredictable nature and variable clinical behavior of the disease, long-term surveillance after resection is recommended. This is a report of a 61-year-old female who presented with a left pleural-based mass with boney invasion found to have a MSFT of the pleura.
Doege-Potter syndrome in a patient with a giant abdominal solitary fibrous tumor: a case report and review of the literature
Published in Acta Clinica Belgica, 2023
Joris Rötgens, Bruno Lapauw, Guy T’Sjoen
Anatomopathological review confirmed the diagnosis of a solitary fibrous tumor. There was no invasion of the adrenal gland, the kidney, the inferior vena cava or the liver. The cutting edges were free of tumor. Surprisingly the liver tumor, which also was completely removed, was not a metastasis of the SFT but was a pleiomorphic adenoma, which is another rare tumor. Removal of the mass solved the hypoglycemia. After surgery, serum IGF-II showed a comparable value of 489 ng/mL (normal: 280–610 ng/mL) while IIE (68–88) peptide decreased and normalized by a value of 15.3 µg/L (6.6 times lower than the initial preoperative value) (normal: 9.0–27). Based on the resection (R0) and histologic features, our multidisciplinary oncology board advised further observation rather than adjuvant radiotherapy or chemotherapy.
Surgical removal of orbital tumors by orbital approach using ultrasonic surgical system SONOPET®
Published in Orbit, 2022
Álvaro Bengoa-González, María-Dolores Lago-Llinás, Enrique Mencía-Gutiérrez, Agustín Martín-Clavijo, Elena Salvador, Mónica Gimeno-Carrero
Some tumors were more ill-defined, with many adhesions and a more solid consistency, such as the solitary fibrous tumor. In this cases, the SB tip was ideal for breaking the fibrous adhesions until normal orbital fat was reached (Figure 3a,b). Another patient had a fronto-orbital epidermoid cyst involving the posterolateral orbit. He had undergone four previous interventions by the neurosurgeons using frontal craneotomies with subdural access. CT revealed a large mass in the right lateral orbital wall, expanding into the extraconal space, the right greater sphenoidal wing, and the orbital roof, destroying the lateral orbital wall. The consistency in this case was softer, so we debulked the tumor using the STS tip, thus improving the proptosis (Figure 3c–f).
A giant solitary fibrous tumour of the liver: a case report
Published in Acta Chirurgica Belgica, 2023
Jan Roman, Petr Vávra, Michaela Vávrová, Vladimír Židlík, Anton Pelikán
Histologic findings showed a solitary fibrous tumour (SFT) of unknown biological behaviour. Microscopically, it was hypercellular, consisting of cells with elongated hyperchromatic nuclei, without atypical signs (Figures 2 and 3). The tissue was partially necrotic. There were no signs of increased mitotic activity or invasion of surrounding structures. Immunohistochemical analysis showed strong positivity of CD34, STAT6, Bcl2, CD99, caldesmon, and focally calponin. Other markers (actin, desmin, S100, CD117, DOG1, CD10, EMA, CKAE1/3 and oestrogen) were negative. Proliferation activity in Ki67 was 3%. The resection line was free of tumorous cells, resulting in a R0 resection of the tumour, gall bladder histology only showed chronic inflammation.