China
Africa
Explore chapters and articles related to this topic
Stammering and voice
Published in Trudy Stewart, Stammering Resources for Adults and Teenagers, 2020
An SLT working with a PWS should always seek medical opinion if voice change is persistent, lasting more than 2–3 weeks, according to the latest guidance from Cancer Research UK. Though unlikely, laryngeal cancer should always be considered as a possible reason for voice change. Early detection of laryngeal cancer is essential for the best chance of survival, response to treatment and quality of life after cancer (Mathieson 2001). Other ‘red flags’ to be aware of include: Difficulty swallowingWeight lossA cough that doesn’t go awayShortness of breath.3
Tumours of the Larynx
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Vinidh Paleri, Stuart Winter, Hannah Fox, Nachi Palaniappan
As with other cancers, laryngeal cancer may present with local symptoms or those due to metastatic spread to nodes or beyond. Occasionally, patients present with general systemic signs, such as weight loss or anaemia, but in laryngeal cancer these are rare in the absence of local symptoms. Paraneoplastic phenomena such as peripheral neuropathy and rashes are very rare. As a result, it is possible to provide primary care workers (and indeed the general population) with a fairly accurate idea of ‘warning/red flag’ symptoms that require urgent referral to an otolaryngologist.
Ear, Nose and Throat (ENT) and Head and Neck
Published in Kaji Sritharan, Samia Ijaz, Neil Russell, Tim Allen-Mersh, 300 Essentials SBAs in Surgery, 2017
Kaji Sritharan, Samia Ijaz, Neil Russell, Tim Allen-Mersh
The most common presentation of laryngeal cancer is with: DysphagiaOdynophagiaHoarse voiceCervical lymphadenopathyHaemoptysis
Early-stage glottic cancer of rare squamous cell carcinoma variants: a population-based study
Published in Acta Oto-Laryngologica, 2023
Yukinori Takenaka, Atsuhiko Uno, Hidenori Tanaka, Norihiko Takemoto, Hidenori Inohara
Our study has several strengths. The first is the use of SEER data. Using this vast database, we identified and analyzed a considerable number of rare SCC variants. Second, we limited our study to only cases of glottic cancer. Glottic and nonglottic cancers exhibit different characteristics. Because of affluent lymphatic drainage, lymph node metastasis is often seen in nonglottic laryngeal cancer, resulting in a poorer prognosis than in glottic cancer [4]. In addition, the etiology was different. Smoking has a greater impact on the development of glottic cancer, whereas drinking has a greater impact on the development of supraglottic cancer [4]. This difference in etiologic causes results in a predilection for different second primary malignancies and can affect the overall survival. Therefore, analysis of different subsites should be avoided. Third, we analyzed only early-stage diseases. Advanced stage laryngeal cancer is usually treated with chemoradiation therapy or surgery, with or without (chemo) radiation. Chemotherapy regimens and the sequence of radiation and chemotherapy vary widely between institutions. This will hamper proper comparison of prognosis. Therefore, we only analyzed stage I and II diseases.
Course of social support and associations with distress after partial laryngectomy
Published in Journal of Psychosocial Oncology, 2022
Julia Roick, Andreas Dietz, Sven Koscielny, Friedemann Pabst, Kerstin Breitenstein, Jens Oeken, Elke-Juliane Schock, Andreas Boehm, Iwona Winter, Jens Büntzel, Andreas Müller, Stefan K. Plontke, Michael Herzog, Susanne Singer
The present study has a few methodological limitations. First, the attrition rate and the high number of missing data must be mentioned. Although dropouts and study completer did not differ in mental health and in social support, the present results may be biased. Second, other factors than social support seem more relevant for mental health since our models explained only up to 10% of the variance. It would also have been informative to additionally ascertain received social support of the participants and their network size and its changing structure. Also, speaking abilities and swallowing disorders, which were not quantified in the study, may represent important influencing factors. Third, the use of a consecutive sample may lead to common similarities among the study population and between patients from the same clinic. Therefore, the study results may not be generalizable to other patients since we investigated a specific subgroup of patients with laryngeal cancer (partial laryngectomy). However, because of the multicenter study design and the low number of patients who refused to take part in the study (6%), the study has a high level of external validity. Despite these limitations, the present findings offer insights into changes in social support between three measurement points and its associations with mental health as a results of data collection across 15 treatment centers. Moreover, we did not exclude those 26 participants who were too distressed to participate at t1 and included them at a later measurement point to have a more representative study population.
Decrement of prognostic nutrition index in laryngeal diseases: from precancerous lesion to squamous cell carcinoma
Published in Acta Oto-Laryngologica, 2021
Wu Daquan, Wang Tian, Na Shen, Liu Danzheng, Huang Xinsheng
Laryngeal squamous cell carcinoma (LSCC) is the most common malignant tumor in head and neck squamous cell carcinoma (HNSCC), accounting for 1–2% of systemic malignancy. The treatment for LSCC includes surgery, radiotherapy and chemotherapy. Although great changes in medical technology have been achieved over the past few decades, the 5-year survival rate of laryngeal cancer has decreased [1]. Risk factors for LSCC include smoking, alcohol intake and HPV infection. Patients with a history of LPL are more likely to develop LSCC. About 90% cases of laryngeal carcinomas are reported to develop from precancerous epithelial lesions [2]. Besides, the overall mean time between the diagnosis of severe dysplasia and its progression to invasive carcinoma was 4.1 years [3]. Therefore, an early diagnosis would be crucial to prevent the development of an invasive neoplasm and the consequent invasive treatment. However, an early diagnosis of the invasive progression of LPL remains to be clarified.