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Gastrointestinal tract and salivary glands
Published in A Stewart Whitley, Jan Dodgeon, Angela Meadows, Jane Cullingworth, Ken Holmes, Marcus Jackson, Graham Hoadley, Randeep Kumar Kulshrestha, Clark’s Procedures in Diagnostic Imaging: A System-Based Approach, 2020
A Stewart Whitley, Jan Dodgeon, Angela Meadows, Jane Cullingworth, Ken Holmes, Marcus Jackson, Graham Hoadley, Randeep Kumar Kulshrestha
In the duodenum CT can play a vital role in assessing traumatic duodenal injury, primary inflammatory processes and secondary involvement from pancreatitis, developmental abnormalities, infectious processes and duodenal neoplasms [27].
Other Tumours of the Colon and Rectum
Published in Peter Sagar, Andrew G. Hill, Charles H. Knowles, Stefan Post, Willem A. Bemelman, Patricia L. Roberts, Susan Galandiuk, John R.T. Monson, Michael R.B. Keighley, Norman S. Williams, Keighley & Williams’ Surgery of the Anus, Rectum and Colon, 2019
Treatment modality and oncological outcome vary with histological types, but surgery usually represents the first-line therapy. Small bowel gastrointestinal stromal tumours and duodenal neoplasms will not be described in this chapter.
Appropriate endoscopic treatment selection and surveillance for superficial non-ampullary duodenal epithelial tumors
Published in Scandinavian Journal of Gastroenterology, 2021
Kingo Hirasawa, Yuichiro Ozeki, Atsushi Sawada, Chiko Sato, Ryosuke Ikeda, Masafumi Nishio, Takehide Fukuchi, Ryosuke Kobayashi, Makomo Makazu, Masataka Taguri, Shin Maeda
Ninety-eight percent (185/189) of the registered patients received surveillance, followed by endoscopic and tumor marker blood sampling in median periods of 36 months (range 6–132). Among these patients, 5 patients were histologically diagnosed with submucosal invasive cancers after ER (Table 2). One patient underwent an additional pancreatoduodenectomy and was then found to have a lymph node metastasis; the patient subsequently died of the disease. Three patients died, and one had metachronous recurrence of the ileum segment of intestinal cancer during the follow-up. Table 3 shows clinicopathologic characteristics of eight patients with death during the follow-up. Two deaths were attributed to the primary duodenal neoplasms, which invaded the submucosa, while the other patients died of other causes. Thus, the 1-year, 3-year, and 5-year OS were 98.4%, 95.5%, and 92.2%, respectively (Figure 4(A)). Table 4 shows the clinicopathologic characteristics of nine cases with recurrence during the follow-up. Local recurrence occurred in four patients, all of whom underwent an incomplete resection of the mucosal lesions and were treated with repeat ER. Two patients had metastatic recurrence and eventually died of the primary duodenal carcinoma. One patient had secondary advanced carcinoma in the ileum and underwent curative surgery. The remaining two patients had metachronous mucosal duodenal neoplasms. Therefore, the 1-year, 3-year, and 5-year DFS was 97.7%, 91.3%, and 83.5%, respectively (Figure 4(B)).
Outcome after Surgical Treatment of Gastrointestinal Stromal Tumors in the Second Part of Duodenum: Is Localized Resection Appropriate?
Published in Journal of Investigative Surgery, 2022
Hany M. El-Haddad, Mohammed I. Kassem, Gihan A. Shehata, Islam A. El-Sayes
Duodenal GISTs (DGISTs) are rare, accounting for 1%–5% of all GISTs. However, they comprise 20% of all small intestinal GISTs and 30% of all duodenal neoplasms [2–4]. Small early lesions are usually asymptomatic; pain and bleeding are the most frequently encountered presentations [3]. Currently, the modified Miettinen classification [5] is used to determine the malignant behavior of these tumors based on their mitotic activity, site, and size.