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Benign tumors
Published in Archana Singal, Shekhar Neema, Piyush Kumar, Nail Disorders, 2019
Extraskeletal or soft tissue chondroma is thought to derive from the connective tissue, not preexisting chondrocytes.226 Clinically, it mimics parosteal chondroma. The clinical differential diagnosis comprises a number of other chondromatoses that rarely affect the digits, such as synovial chondromatosis. Histopathologically, all chondromas are characterized by a proliferation of hyaline cartilage irregularly arranged cells, but without mitoses or cellular atypias. In the differential diagnosis, chondroblastoma and chondrosarcoma are important.
Musculoskeletal tumours
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
Chondroblastoma (Figure 37.18) is a benign cartilage-producing tumour that occurs in the epiphyses of bones in children. It is most common around the knee. Pain is often severe, with associated inflammation and possibly joint effusion. Radiologically, there is an often barely visible lytic lesion in the centre of the epiphysis. The diagnosis is often missed, and isotope bone scan can help identify the lesion.
Musculoskeletal (including trauma and soft tissues)
Published in Dave Maudgil, Anthony Watkinson, The Essential Guide to the New FRCR Part 2A and Radiology Boards, 2017
Dave Maudgil, Anthony Watkinson
The following locations are typical for the associated conditions. True or false? Implantation dermoid – terminal phalanx.Cortical desmoid – distal tibia.Chondroblastoma – epiphysis.Osteofibrous dysplasia – humerus.Intraosseous lipoma – calcaneum.
Distal Femoral Non-Epiphyseal Cortical Chondroblastoma Confirmed with H3F3B p. Lys36Met Mutation
Published in Fetal and Pediatric Pathology, 2023
Haiyan Gu, Lingling Sun, Jiufa Cui, Lan Yu, Jigang Wang
Chondroblastoma is a primary cartilaginous tumor that mainly occurs in the second to early third decades of life with a male predominance (male/female ratio: 2:1) [1]. Most authors agree that it arises from secondary ossification centers in the epiphyseal plates and apophyses of long bones in patients with an immature skeleton or some remnant of it, so the typical localization for chondroblastoma is the epiphysis. A tumor localizing within the metaphysis or diaphysis is generally not considered chondroblastoma. Maheshwari et al. [7] reviewed 690 cases of chondroblastoma in 10 large series and found about 2% were purely metaphyseal, and only one was in the diaphysis. They also reported 7 cases of metaphyseal and diaphyseal chondroblastoma, and most patients were adolescents with a slight female predominance [7]. Previous studies noted that chondroblastoma at non-epiphyseal sites such as short tubular bones or flat bones tended to affect adult patients older than 30, so the etiology of metaphyseal and diaphyseal chondroblastoma may be different from these tumors [11].
Intra-osseous tophaceous gout of a bipartite patella mimicking aggressive bone tumour
Published in Modern Rheumatology Case Reports, 2021
Fidelis Marie Corpus-Zuñiga, Keiichi Muramatsu, Ma. Felma Rayel, Yasuhiro Tani, Tetsuya Seto
A giant cell tumour (GCT) is one of the most common cause of solitary tumours in the patella. Characteristic image findings often show a lytic lesion that involves almost the whole patella with an ill-defined narrow zone of transition to normal bone. Cortical appearance is usually expanded and thinned, rarely finding a sclerotic rim and there is no periosteal reaction [12]. Chondroblastoma is also considered because of the solitary nature of the tumour, the age and gender of the patient, and lastly because the ossification of the patella is similar to that of an epiphysis or apophysis of a long bone. MRI findings characteristic of a chondroblastoma of the patella are of cartilaginous appearance, and edoema around the bony lesion and soft tissues [12]. Osteoid osteoma was also one of differential diagnosis, but based on the patient’s history, he did not exhibit localised pain during the night. The characteristic radiographic appearance is that of a lytic lesion with sharp margins with a nidus of small central ossification. But CT scan and MRI didn’t demonstrate a nidus and inflammatory bony lesion around nidus in this case. Aneurysmal bone cyst is also one of our considerations, but it is unlikely because the patient did not demonstrate a bulging growth of the patella. MRI showed no septations and fluid levels [12].