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The Mediastinum (including pre-and para-spinal lines, neural tumours, and pneumomediastinum).
Published in Fred W Wright, Radiology of the Chest and Related Conditions, 2022
The Carney syndrome is discussed on p. 5,17. Illus. CHEMODECTOMA, Pt. 3a-e shows a chemodectoma arising in an aortic body, andIllus. CHEMODECTOMA, Pt. 4a-c a chemodectoma arising in a pulmonary body - see alsoIllus. PHAEOCHROMOCYTOMA.
Jugular Foramen Lesions and their Management
Published in John C Watkinson, Raymond W Clarke, Christopher P Aldren, Doris-Eva Bamiou, Raymond W Clarke, Richard M Irving, Haytham Kubba, Shakeel R Saeed, Paediatrics, The Ear, Skull Base, 2018
The term paraganglioma is derived from the site of origin of the tumour. In the temporal bone, paraganglia are present in the adventitia of the jugular bulb and along the IXth and Xth cranial nerves, and in the middle ear in association with Jacobsen’s plexus. Chromaffin and non-chromaffin paragangliomas have been distinguished according to their intrinsic ability to take up and stain with chromium salts. In the past, a chromaffin paraganglioma was considered capable of producing adrenalin, whereas its non-chromaffin counterpart was not. This distinction between chromaffin and non-chromaffin paragangliomas has since become outdated, as both tumours are now known to synthesize all types of catecholamines. The term chemodectoma should be reserved for tumours that originate from the chemoreceptor system. The paraganglia in the temporal bone do not belong to this histological entity, in contrast with those in the carotid sinus. Therefore, the term chemodectoma is less appropriate for lesions in the jugular foramen and in other parts of the temporal bone.
Pharynx, Larynx and Neck
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
This is a rare tumour that has a higher incidence in areas where people live at high altitudes because of chronic hypoxia leading to carotid body hyperplasia. The tumours most commonly present in the fifth decade and approximately 10% of patients have a family history. There is an association with phaeochromocytoma. The tumours arise from the chemo- receptor cells on the medial side of the carotid bulb and, at this point, the tumour is adherent to the carotid wall. The cells of the chemodectoma are not hormonally active and the tumours are usually benign with only a small number of cases producing proven metastases (Figure47.55).
The carotid body and associated tumors: updated review with clinical/surgical significance
Published in British Journal of Neurosurgery, 2019
Nasir Butt, Woong Kee Baek, Stefan Lachkar, Joe Iwanaga, Asma Mian, Christa Blaak, Sameer Shah, Christoph Griessenauer, R. Shane Tubbs, Marios Loukas
Over the years, authors have attributed CBTs with different names: chemodectoma, paraganglioma, chromaffinoma, non-chromaffin tumor, and glomus tumors. CBTs can either be nonfunctional chemodectomas or functional apudomas. The later secretes neuropeptides and is associated with activity of the sympathetic nervous system.15 The carotid body is part of the paraganglion system, hence the term for tumor arising in it: paraganglioma.