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Histopathological Cancer Detection Using CNN
Published in Meenu Gupta, Rachna Jain, Arun Solanki, Fadi Al-Turjman, Cancer Prediction for Industrial IoT 4.0: A Machine Learning Perspective, 2021
Soham Taneja, Rishika Garg, Preeti Nagrath, Bhawna Gupta
Colorectal Cancers – This term refers to cancers of the colon and the rectum, also called bowel cancer. It is the development of cancer from the colon or rectum (parts of the large intestine) and usually requires surgery for treatment. This cancer is curable as well, although it can recur after surgery, often resulting in fatalities. However, early detection can reduce the need for surgery, thereby helping the patient heal fully. Hence, we expect our solution to be capable of working in favor of this goal.
General surgery
Published in Kaji Sritharan, Jonathan Rohrer, Alexandra C Rankin, Sachi Sivananthan, Essential Notes for Medical and Surgical Finals, 2021
Kaji Sritharan, Jonathan Rohrer, Alexandra C Rankin, Sachi Sivananthan
Screening can reduce the risk of death from bowel cancer by » 16%. By 2009, the NHS Bowel Cancer Screening Programme will be fully operational. Men and women aged 60–69 years old will be routinely screened every two years using FOB testing kits. Those >70 years can request to be screened. Abnormal results will be investigated with colonoscopy.
Cancer
Published in Sally Robinson, Priorities for Health Promotion and Public Health, 2021
Common symptoms of bowel cancer include bleeding from the rectum and blood in the stoolsa change in normal bowel habitsa feeling of needing to visit the toilet even after having beenweight losspain in the rectum or abdomenfatigue
Computer-aided classification of colorectal segments during colonoscopy: a deep learning approach based on images of a magnetic endoscopic positioning device
Published in Scandinavian Journal of Gastroenterology, 2023
Britt B. S. L. Houwen, Fons Hartendorp, Ioanis Giotis, Yark Hazewinkel, Paul Fockens, Taco R. Walstra, Evelien Dekker
This study was designed to evaluate the diagnostic accuracy of deep learning models for the classification of the colorectal segment, based on images of the MEI positioning device. The study is reported according to the STARD statements [18]. For this study we used the data of a prospective multicenter study in which a computer-aided diagnosis (CADx) for optical diagnosis of diminutive polyps was developed, validated and benchmarked against the performance of screening endoscopists (POLyp Artificial Recognition [POLAR] system) (Houwen B, 2022, unpubl. data). This study was conducted from October 2018 to September 2021 in eight regional Dutch hospitals and one academic Spanish hospital in partnership with ZiuZ Visual Intelligence (Gorredijk, the Netherlands). Data were collected during colonoscopies in the context of the bowel cancer screening and surveillance program or for the evaluations of symptoms. The detailed methods and results of this study are described elsewhere (online). For this study, we used prospectively collected training data from one center in which the MEI device was used during the study procedures.
Doing, being, becoming, and belonging: Experiences transitioning from bowel cancer patient to survivor
Published in Journal of Occupational Science, 2023
Elizabeth Martin, Clare Hocking, Margaret Sandham
Occupational transitions involve movement from one life phase, condition, or status to another (Scalzo et al., 2016). They are a normal part of life (Christiansen & Townsend, 2010), affecting people’s identity and life course (Walder & Molineux, 2017), and are thus worthy of study. Bowel cancer is the fourth most common cancer worldwide (Rawla et al., 2019) and increasing survivorship (Hawkins et al., 2015; Husson et al., 2015; Lee et al., 2015) offers an opportunity to study sudden and unexpected transitions associated with life threatening illness and the associated changes in body structures and functions. This article explores the occupational impact of transitioning from bowel cancer patient to survivor. There is disparity concerning when an individual becomes a survivor, with definitions beginning at diagnosis, end of treatment, or after a disease-free period (Drury et al., 2017). In this study, the term refers to those who have completed cancer treatment.
Andrographolide Induces Apoptosis and Cell Cycle Arrest through Inhibition of Aberrant Hedgehog Signaling Pathway in Colon Cancer Cells
Published in Nutrition and Cancer, 2021
Imran Khan, Sadaf Mahfooz, Mohammad Faisal, Abdulrahman A. Alatar, Irfan A. Ansari
Colorectal cancer (CRC) is also known as colon or bowel cancer, which is one of the main reasons of morbidity and deaths around the world (1). In the year 2016, accounting for approximately 1,400,000 new cases and 7,000,000 deaths, it stands to be the third most common cause of cancer associated deaths worldwide (2). Moreover, according to recent updates from GLOBOCAN 2018 report, it is projected that by the year 2035, global prevalence of CRC may rise up to 14 million new cases (3). Commonly implemented therapeutic strategies for CRC include surgical resection and radiotherapy accompanied by adjuvant chemotherapeutic drugs like oxaliplatin and 5-fluorouracil (4). This rigorous treatment regime is often accompanied by several unwanted side effects and complication like cardiotoxicity, chest pain, and also chemoresistance (5,6). Thus, the present research scenario demands identification of new therapeutic agents which possess the potential to suppress different signaling pathways associated with CRC carcinogenesis.