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Functional Rehabilitation
Published in James Crossley, Functional Exercise and Rehabilitation, 2021
A limp is a form of antalgic gait. A client might limp after spraining an ankle, causing damage to ligaments and local swelling. In the early stages of injury, antalgic movement patterns like a limp are useful becasaue they trigger changes in movement to reduce loading compromised tissue.
Unexplained Fever Associated with Musculoskeletal Disorders
Published in Benedict Isaac, Serge Kernbaum, Michael Burke, Unexplained Fever, 2019
Sacroiliitis27 — A buttock pain is the first symptom, radiating in about half of the cases to the posterior face of the thigh. A limp is often present. Pain may be induced by pressure on the joint or (of greater value) by orthopedic maneuvers which produce sacroiliac joint movement.
Chiari osteotomy
Published in K. Mohan Iyer, Hip Preservation Techniques, 2019
Most patients who are candidates for a Chiari osteotomy have a limp and a Trendelenburg gait preoperatively. Usually only the antalgic portion of a limp will be improved by the procedure. In general, advise patients that their Trendelenburg lurch may not improve and can worsen postoperatively because the traditional surgical approach involves stripping of the tensor and much of the abductor musculature from the lateral iliac wall. Some authors have reported an improvement in the Trendelenburg lurch in a majority of patients, attributing the improvement to the medialized hip center and to advancement of the greater trochanter in some patients.
Pomegranate peel extract ameliorates the severity of experimental autoimmune encephalomyelitis via modulation of gut microbiota
Published in Gut Microbes, 2020
Xin-Yu Lu, Bing Han, Xin Deng, Si-Ying Deng, Yan-Yan Zhang, Pei-Xin Shen, Teng Hui, Rui-Heng Chen, Xing Li, Yuan Zhang
Female C57BL/6 mice (~8 weeks) were purchased from SPF (Beijing) Biotechnology CO., ltd. Mice were housed at the in-house animal care facility of Shaanxi Normal University animal under a 12-hour day-night-cycle and standardized conditions (23°C ± 2°C). All experiments were approved by the Institutional Animal Care and Use committee of Shaanxi Normal University and were in accordance with the approved institutional guidelines and regulations. EAE was induced according to our previous study.19,20 EAE mice were randomly divided into two treatment groups, 100 mg/kg PPE or solvent (PBS) were applied daily via oral gavage, at the first day of immunization, onset of disease (10 d), and peak of disease (16 d). After immunization, mice were assessed clinically in a blinded manner using a disease severity scale that is scored according to a 0–5 scale as described previously.20 Briefly, 0, no clinical symptoms; 0.5, stiff tail; 1, limp tail; 1.5, limp tail and stagger gait; 2, paralysis of one limb; 2.5, one limb was paralyzed and the other was faint; 3, both hind limbs were completely paralyzed; 4, moribund; and 5, death.
Henry Herbert Donaldson’s (1857–1938) contribution to an organized approach to the experimental study of the mammalian central nervous system
Published in Journal of the History of the Neurosciences, 2018
Several things served to limit his research effort during his first six years at Chicago. One was that he served as Dean of the Ogden Graduate School of Science from 1892 to 1898. His administrative duties must have required considerable attention as the university went through its formative stage. A second matter that probably slowed his progress was that during this same period he was setting up his laboratory (Anonymous, 1903). Recall that the neurology building was not constructed until July of 1897. He was starting his laboratory in a new school before there were adequate buildings. As if these were not enough, Donaldson also suffered a medical setback. He developed a tubercular infection of the hip joint (Conklin, 1939). As a result, he spent long recuperative visits in Colorado. The infection resulted in a life-long limp.
Peripheral artery disease: the new frontiers of imaging techniques to evaluate the evolution of regenerative medicine
Published in Expert Review of Cardiovascular Therapy, 2019
Marco Miceli, Dario Baldi, Carlo Cavaliere, Andrea Soricelli, Marco Salvatore, Claudio Napoli
Revascularization by surgical bypass or endovascular techniques or surgical reconstruction is used for the treatment of CI in cases where the patient does not respond adequately to conventional medical therapy [67]. Although endovascular therapy improves blood flow and function, there are important risks associated with it, while the duration may be limited, especially in infrainguinal diseases. Despite the good results obtained, at first, by these therapeutic protocols, later, a percentage of treated patients, had a worsening in limp (claudication) or limb critical ischemia (CLI), which requires amputation of the limb [7,51]. In patients with CLI it is estimated that the annual amputation rate is >30% and with a mortality >20% [7].