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Adverse Effects
Published in Barry M. Maletzky, C. Conrad Carter, James L. Fling, Multiple-Monitored Electroconvulsive Therapy, 2019
We have not systematically studied the relationship between quality of oxygenation, therapeutic effect, and headache, though we have not observed any apparent trends in these directions. It would also be of interest to note whether there is any correlation between the level of blood pressure elevations during treatment and the occurrence and severity of headache thereafter. We know of no study systematically examining the persistence of blood pressure changes hours after the seizure has ended. However, the typical description of the headache is not similar to that of a vascular headache and, in checking blood pressures routinely post-MMECT, we have not noted a relationship between persistence in blood pressure changes and complications of headache.
Headache associated with vascular disease: migraine and stroke
Published in Stephen D. Silberstein, Richard B. Upton, Peter J. Goadsby, Headache in Clinical Practice, 2018
Stephen D. Silberstein, Richard B. Upton, Peter J. Goadsby
Headache has been reported after balloon inflation or embolization of arteriovenous malformations or aneurysms.116,117 It is a severe, unilateral pain of abrupt onset that occurs shortly after the procedure and is ipsilateral to the occluded artery. It is localized to specific areas according to the artery involved: the temple for the proximal middle cerebral artery, the retroorbital area for the middle of the middle cerebral artery stem, the lateral part of the neck for the upper vertebral artery, and the vertex and occiput for the inferior portion of the basilar artery. This pain is nonthrobbing and not associated with other symptoms. It is most likely due to distention of the arterial wall and provides a good model of pure vascular headache. By contrast, pain is not mentioned in the largest series (23 patients) so far published of angioplasty for atherosclerotic intracranial stenosis.118
Etiology of RSD
Published in Hooshang Hooshmand, Chronic Pain, 2018
One common situation is when a child falls off a swing at the school grounds or is involved in a car accident and is unconscious for a few seconds, has some headache, neck pain, and vomiting for a few days, and then everything clears up. The problem reappears as severe vascular headache years later. In such patients, careful evaluation of cervical spine can discover the cervical spine pathology.
Developments in distinguishing secondary vascular headache from primary headache disorders in clinical practice
Published in Expert Review of Neurotherapeutics, 2021
Even though a first and worst ever onset headache means subarachnoid hemorrhage until proven otherwise, thus requiring investigation with CT and lumbar puncture, many admitting physicians do not feel confident in recognizing thunderclap headaches. Many patients do not provide a textbook description and many non-neurologists find it difficult to understand what a true thunderclap is. We have seen many unnecessary LP’s on one hand and dismissal of a relatively good description on the other. We find the two questions of immense help; if the pain felt like a hit from a baseball or cricket bat and if the headache reached its peak in 5 min. We rarely see sub-hyloid hemorrhage and many patients don’t have the typical Kernig’s or Brudzinsky’s sign. Although sub-arachnoid hemorrhage is the most common cause of secondary thunderclap headache, many other vascular headaches for example, pituitary apoplexy, carotid dissection and cerebral venous thrombosis could present this way.
Role of developmental venous anomalies in etiopathogenesis of demyelinating diseases
Published in International Journal of Neuroscience, 2019
Siddika Halicioglu, Sule Aydin Turkoglu
Study Design: The study was conducted in accordance with the principles of the Helsinki Declaration and approved by the local Institutional Review Board (2016/55). Cranial MRIs of patients who were admitted to the neurology department of our tertiary center between the years 2012–2016 and diagnosed as having relapsing-remitting MS (RRMS) according to the McDonald criteria were retrospectively included into the patient group of the study (n = 105). Cranial MRI images of patients with vascular headache who presented with symptoms of headache and had no pathologic lesions in cranial MRI were evaluated as the control group. A total of 210 patients were included in the study. In the case group, MR images of patients with RRMS and RIS diagnoses with McDonald criteria followed in our clinic were included in the study. Apart from MS, other cases of immunologic disease such as malignancy, meningoencephalitis and vasculitis were excluded. Patients whose MR images were not available or centered externally excluded from the study. In the control group, cases with MR findings such as vasculitis, meningoencephalitis and malignancy were excluded.
In-vitro and in-vivo respiratory deposition of a developed metered dose inhaler formulation of an anti-migraine drug
Published in Drug Delivery, 2019
Ebtsam M. Abdou, Soha M. Kandil, Amany Morsi, Maysa W. Sleem
Migraine headache is the most common neurological vascular headache disease which causes a throbbing and pulsating pain around the head due to brain and scalp arteries dilating resulting in terrible pain in the head (Green et al., 2005). Migraine treatment usually requires the drug to be accessed through the systemic circulation as the target tissue here, which is the brain, cannot be accessed through local therapy. So, rapid drug delivery to the circulation is required (Misra et al., 2003). Studies have shown that migraine patients consider rapid onset, complete and lasting pain relief, and medication side effects as the most important factors when choosing a migraine treatment (Gallagher, 2004).