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Inflammation and Infection
Published in Manoj Ramachandran, Tom Nunn, Basic Orthopaedic Sciences, 2018
Vikas Khanduja, Sertazniel Singhkang, Manoj Ramachandran
Antibiotics can be delivered in a variety of ways: Oral.Intramuscular.Intravenous and home intravenous therapy (via Hickman line).Antibiotic beads and spacers:aminoglycosides are impregnated in polymethylmethacrylate (PMMA) cement and used to treat infected total joint arthroplasty and osteomyelitis.the antibiotic used in this form is stable during the process of PMMA polymerization.elution of antibiotic from PMMA is for a maximum of 6–8 weeks.this form delivers a very high local concentration of the antibiotic.Osmotic pump: delivers high concentration of antibiotic locally. Useful for osteomyelitis.
Drawing Back the Curtains on Motivation
Published in Marc D. Feldman, Gregory P. Yates, Dying to be Ill, 2018
Marc D. Feldman, Gregory P. Yates
Because I was in intensive care so much, I ended up having a Hickman line installed, which ended near my heart. This was a terrible idea. The line just created more opportunities for me. I could take blood out of the line any time I wanted, or put other stuff down it, like toilet water, or tap water. I would never put anything solid into the tube, because I didn’t want to die from a pulmonary embolism. My intention wasn’t to kill myself—just to live as close to the edge of life as possible.
Yasmin’s story
Published in Viv Martin, Karen Forbes, Developing a Narrative Approach to Healthcare Research, 2018
When I next see Yasmin, we talk more about her attempted suicide. In the intervening two months she has spent yet more time in hospital through severe infection and dehydration. Her Hickman line, the catheter in her chest used for long-term intravenous access, had become severely infected, and had required surgery to remove it. The infection then spread into her blood stream. In addition, she had become seriously dehydrated and close to kidney failure.
Development and validation of a model for predicting the risk of suicide in patients with cancer
Published in Archives of Suicide Research, 2023
Lin Du, Hai-Yan Shi, Yan- Qian, Xiao-Hong Jin, Hai-Rong Yu, Xue-Lei Fu, Hua Wu, Hong-Lin Chen
Several limitations should be considered in our study. Firstly, the samples taken from inpatients, this study may limit generalization to patients from other setting, such as outpatients and tumor hospital. In addition, some information is needed be considered in the future studies, on the common reasons for admission in the hospital, such as chemotherapy, surgery, post-chemo vomiting and hypokalemia, siting of a Hickman line, sepsis, neutropenic sepsis because the thresholds are likely to be very different in different countries, which may also limit the generalization of findings. Secondly, although the use of the item-9 in the PHQ-9 to evaluate SI has been widely recognized, due to the patients’ stigma about the disease and the effects of social desirability bias, which may lead to partial bias. Thirdly, unconscious patients or patients with serious physical diseases who cannot participant in the study independently were excluded, which might lead to some selection bias and underestimated the prevalence of SI in cancer patients in this study. Finally, due to differences in patients' understanding of the questionnaire questions, this may result in partial bias.
Home Total Parenteral Nutrition for Intestinal Failure in Patients with Advanced Small Intestinal Neuroendocrine Neoplasms
Published in Nutrition and Cancer, 2021
Man Liu, Faidon-Marios Laskaratos, Jose Bennell, Jie Chen, Christos Toumpanakis, Dalvinder Mandair, Martyn Caplin
Death was the most common reason for TPN discontinuation, e.g., Patient Nos. 3, 4 and 5. Patient No. 4 developed Hickman line-associated septicemia 3 mo, after TPN initiation and had a trial of enteral nutrition, thus discontinuing TPN. Two months later, having failed to maintain an enteral diet, this patient restarted TPN for 5 mo, and re-developed septicemia, which led to another discontinuation of TPN. During that time, she slowly built up an appropriate enteral calorie intake. Two and half years later, the patient developed severe SBO with low albumin and gross peripheral edema and restarted TPN surviving on TPN for a further 4 mo (Table 2).