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Gastrointestinal system
Published in Jagdish M. Gupta, John Beveridge, MCQs in Paediatrics, 2020
Jagdish M. Gupta, John Beveridge
6.8. Which of the following statements is/are true of intestinal sugar intolerance?Hereditary lactose intolerance usually presents before the age of 2 years.Hereditary glucose/galactose malabsorption can be treated by a lactose-free soya formula.Infants can develop disaccharide intolerance following infectious diarrhoea.Lactose intolerance can be diagnosed by measuring expired breath hydrogen.Small bowel bacterial overgrowth can present with symptoms of sugar intolerance.
Common/useful drugs
Published in Jonathan P Rogers, Cheryl CY Leung, Timothy RJ Nicholson, Pocket Prescriber Psychiatry, 2019
Jonathan P Rogers, Cheryl CY Leung, Timothy RJ Nicholson
Caution: GI obstruction (inc subacute), ↑QTc*, avoid if hereditary galactose intolerance (Lapp lactase deficiency or glucose-galactose malabsorption), L (unless mild), P/B.
Normal and Abnormal Intestinal Absorption by Humans
Published in Shayne C. Gad, Toxicology of the Gastrointestinal Tract, 2018
David W. Hobson, Valerie L. Hobson Balldin
Sucrose-isomaltase deficiency in the small intestine is an autosomal recessive inherited disorder. Significant portions of the Inuit population in Greenland have this type of a sucrose-isomaltase deficiency. If placed on low-sucrose diets, these individuals show few problems. There is also a glucose-galactose malabsorption syndrome that is due to a defect in active transport for these monosaccharides, although fructose is well tolerated and can be substituted [60].
Antihistamines-refractory chronic pruritus in psoriatic patients undergoing biologics: aprepitant vs antihistamine double dosage, a real-world data
Published in Journal of Dermatological Treatment, 2022
Giovanni Damiani, Khalaf Kridin, Alessia Pacifico, Piergiorgio Malagoli, Paolo D. M. Pigatto, Renata Finelli, Fabio S. Taccone, Lorenzo Peluso, Rosalynn R. Z. Conic, Nicola L. Bragazzi, Marco Fiore
Exclusion criteria comprehended: (i) pediatric patients (<18 years) or pregnant woman, (ii) different type of psoriasis (i.e. erythrodermic psoriasis, guttate psoriasis, impetigo herpetiformis, pustular psoriasis, drug-induced psoriasis), (iii) the presence of acute or chronic infections (HIV, hepatitis B and C, tuberculosis), (iv) renal, hepatic or metabolic conditions able to induce pruritus, (v) other concomitant autoimmune/auto-inflammatory conditions except psoriatic arthritis or psoriatic spondylitis, (vi) concomitant dermatoses, atopic background, or even history of positive patch test, (vii) drugs recently introduced (<3 months) or capable to trigger pruritus, (viii) use of medical contraceptives, (ix) hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency, (x) ongoing therapies with pimozide, terfenadine, astemizolo, cisapride, or ergot derivates, (xi) active disease or even history of psychiatric diagnoses, (xii) VAS <6mm.
Safety of bazedoxifene in Korean women with post-menopausal osteoporosis: a post-marketing surveillance study (PMSS)
Published in Expert Opinion on Drug Safety, 2019
Ji Wan Kim, Ji Young Lee, Hyung-Eun Park, Sang-Hee Kim, Yoon-Sok Chung
Women for whom the treatment and prevention of postmenopausal osteoporosis were required were eligible for enrollment in this study. Subjects were excluded if they had hypersensitivity to the active substance or any of the excipients, had an active or past history of venous thromboembolic events including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis, or unexplained uterine bleeding. In addition, women with signs or symptoms of endometrial cancer, rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption were excluded from this study.