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Human Gut Microbiota–Transplanted Gn Pig Models for HRV Infection
Published in Lijuan Yuan, Vaccine Efficacy Evaluation, 2022
At PCD7, there were significant positive correlations between unclassified members of Clostridiales and Mycoplasmataceae and ileal CD8+ T cells. Splenic CD8+ and CD4+ T cells and ileal CD8+ T cells were negatively correlated with Anaerococcus. A negative correlation also existed between splenic CD4+ T cells and Staphylococcus.
Differences in the oral and intestinal microbiotas in pregnant women varying in periodontitis and gestational diabetes mellitus conditions
Published in Journal of Oral Microbiology, 2021
Xin Zhang, Pei Wang, Liangkun Ma, Rongjun Guo, Yongjing Zhang, Peng Wang, Jizhi Zhao, Juntao Liu
The cladograms display the differently expressed taxa among the four groups. The circle from inside to outside represents the classification levels from phyla to genera. The diameters of the circles represent relative abundances. At the family level, two oral taxa (Desulfobulbaceae and Mycoplasmataceae) and two intestinal taxa (Atopobiaceae and Peptococcaceae) in the periodontitis group, five oral taxa (unidentified_Flavobacteriales, unidentified_Bacillales, Christensenellaceae, Ruminococcaceae and Enterobacteriaceae) and three intestinal taxa (Defluviitaleaceae, Lachnospiraceae and Paracaedibacteraceae) in the GDM group, two intestinal taxa (unidentified_Methanobacteriales and Nostocaceae) in the periodontitis + GDM groups, four oral taxa (Saprospiraceae, Microscillaceae, Rhodocyclaceae and Akkermansiaceae) and one intestinal taxa (Desulfobacteraceae) in the healthy control group were significantly enriched (Figure 4 (c) and (d)).
Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats
Published in Renal Failure, 2023
Wenli Zou, Yueming Liu, Wei Zhang, Bo Lin, Wei Shen, Yiwen Li, Qiang He, Juan Jin
The structure and relative abundance of the flora are shown at the phylum level (Figure 4A), and the major bacterial phyla were Bacteroidetes, Firmicutes, Proteobacteria, Verrucomicrobia, and Spirochetes. Compared with the CON group, the Firmicutes/Bacteroidetes (F/B) ratio in Cef and TAK groups decreased significantly at the fourth week, although there was no significant difference at weeks 0 and 12 among the three groups (Figure 4B). At week 4, compared with the CON group, the abundance of Bacteroidetes in both the Cef and TAK groups increased significantly, as with Actinobacteria the TAK group, but not in the Cef group. The phyla Firmicutes, Verrucomicrobia, Spirochetes, TM7, Tenericutes, and Elusimicrobia were decreased significantly in both the Cef and TAK groups. Phyla Proteobacteria and Deferribacteres were significantly decreased in the TAK group, but not in the Cef group. Phyla Cyanobacteria was significantly decreased in the Cef group, but not in the TAK group. At week 12, the relative abundance of the above phyla were at a similar level among the three groups, with only Tenericutes showing significant differences between the CON and TAK groups (Figure 4C). LEfSe analysis (Figure 4D) was performed by submitting a relative abundance matrix at the genus level and showed the enriched bacteria for each group at the following taxonomic levels: class, order, family, and genus. At the family level, Methanomassiliicoccaceae, Coriobacteriaceae, Bacteroidaceae, RF16, S24-7, Christensenellaceae, Peptococcaceae, Mogibacteriaceae, and Cerasicoccaceae were more prevalent in the TAK group; Bifidobacteriaceae, Moraxellaceae, Spirochaetaceae, and F16 were more prevalent in the CON group; and Odoribacteraceae and Mycoplasmataceae were more prevalent in the Cef group. At the genus level, vadinCA11, Bacteroides, Alistipes, rc4_4, Anaerotruncus, and Mogibacterium were more prevalent in the TAK group; Bifidobacterium and Treponema were more prevalent in the CON group; and Odoribacter, Roseburia, and Mycoplasma were more prevalent in the Cef group.
Prevalence and antimicrobial susceptibility of Ureaplasma species and Mycoplasma hominis in Greek female outpatients, 2012–2016
Published in Journal of Chemotherapy, 2018
Sofia Maraki, Viktoria Eirini Mavromanolaki, Eleni Nioti, Dimitra Stafylaki, George Minadakis
Mycoplasmas, the smallest free-living organisms, are members of the Mycoplasmataceae family and Mollicutes class. They are characterized by lack of cell wall, extremely small genome and limited biosynthetic capabilities.1