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Breast disorders in children and adolescents
Published in Joseph S. Sanfilippo, Eduardo Lara-Torre, Veronica Gomez-Lobo, Sanfilippo's Textbook of Pediatric and Adolescent GynecologySecond Edition, 2019
Nirupama K. De Silva, Monica Henning
Neonatal mastitis is an infection that usually occurs in term or near-term infants32 within the first week of life.31 It affects female infants twice as often as males, and approximately 50% of infants with neonatal mastitis will develop a breast abscess.32 Adolescents may develop nonpuerperal mastitis or a breast abscess as a result of irritation of the skin (through shaving or nipple stimulation), a foreign body (e.g., piercing), or infection of an epidermal cyst.20
Bacteria Associated with Granulomatous Lobular Mastitis and the Potential for Personalized Therapy
Published in Journal of Investigative Surgery, 2022
Xin-Qian Li, Hong-Li Wu, Jing-Ping Yuan, Tian-gang Liu, Sheng-Rong Sun, Chuang Chen
The relationship between GLM and breast cancer is a key concern for doctors and patients. Six cases of non-puerperal mastitis concurrent with breast cancer were identified by PubMed search. Five of the patients involved were diagnosed with GLM. Notably, the stages of breast cancer were very early. The cases included three cases of ductal carcinoma in situ (DCIS) [78–80], two cases of invasive breast carcinoma [81,82] and one case of invasive breast carcinoma and DCIS [83]. Most of the cases involved the right breast [79–83], and over half of the patients were more than 40 years old [78,80,81,83]. However, in only one case was Corynebacterium infection identified, on the same breast as DCIS [78], indicating that further investigation of the association between GLM-associated bacteria and breast cancer is warranted. Nevertheless, patients with a history of non-puerperal mastitis might be at increased risk of breast cancer [84]. Peters et al. [85] found that the risk of breast cancer in patients with non-puerperal mastitis was significantly increased within twelve months after mastitis treatment. Furthermore, a recent study in a large population in China showed that patients with a history of non-lactation mastitis were at high risk for breast cancer, especially those under 50 years of age, of lower socioeconomic status or receiving hormone drugs [86]. However, the intrinsic relationships between non-puerperal mastitis and breast cancer need further investigation.