China
Africa
Explore chapters and articles related to this topic
ExperimentaL Oral Medicine
Published in Samuel Dreizen, Barnet M. Levy, Handbook of Experimental Stomatology, 2020
Samuel Dreizen, Barnet M. Levy
Obstruction of the submaxillary gland duct produced atrophic changes that were well advanced by 3 days and quite severe by 7 days. At 3 days, the glands were reduced in size and the acinar cells were small, having lost basophilia, vacuoles, and secretory granules. The trophochrome cells had disappeared and the secretory tubules were small and lined with cells of reduced height. The inter- and intralobular ducts were dilated. By 7 days, the acini had disappeared and were replaced by islands of small polyhedral cells and connective tissue infiltrated with plasma cells, lymphocytes, and eosinophils. Following removal of the duct obstruction, the glands evidenced regeneration that began within a day and continued for about a week. There was a reappearance of the acinar cells, trophochrome cells, and secretory material. Regeneration was faster in glands ligated for 3 days than in those obstructed 7 days. After 1 week, the unobstructed glands began to form mucoceles in the surrounding connective tissue. Ducts again became obstructed followed by acinar atrophy.
Lysozyme
Published in Masahiko Mori, Histochemistry of the Salivary Glands, 2019
Lysozyme was detected in the intercalated duct cells of the submandibular and parotid glands (Figure 1 a, b). Other glandular cells in these salivary glands were devoid of lysozyme staining. Klockars and Reitamo11 noted that submandibular glands showed positive staining in some serous cells. No immunohistochemical product for lysozyme was given in the parotid gland.11,12 Kraus and Mestecky, using fluorescence microscopy,13 stated that lysozyme in the parotid glands was confined to cells located at basal aspects of striated ducts. In the sublingual gland, lysozyme staining was confined to the demilune cells which are serous elements. No reactive product was obtained in mucous acinar components in either major or minor salivary glands.14 Lysozyme staining in minor salivary glands was usually restricted in serous demilune cells and intralobular duct cells with varying intensities in labial, buccal, lingual, and retromolar glands (Figures 2 a, c). Palatal glands are composed of pure mucous acinar cells and their duct systems. Lysozyme was evident in some intralobular duct and acinar cells, but not all. Von Ebner’s glands of the tongue, consisting of serous acinar components, showed intense staining for lysozyme. Their ductal segments also stained.15 Reitamo et al.16 provided a detailed immunohistochemical distribution of lysozymes in minor glands of mucosal mucosa. The biochemical activity of lysozyme was found only in labial secretions17 (Table 1).
Liver, Gallbladder, and Exocrine Pancreas
Published in Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, Chirukandath Gopinath, Page R. Bouchard, Toxicologic Pathology, 2018
Russell C. Cattley, James A. Popp, Steven L. Vonderfecht
The intercalated ducts fuse imperceptibly to form the intralobular ducts. Neither of these ducts has a significant collagen matrix around them; however, once the ducts leave the lobules, they acquire a variably thick rim of collagen and are termed interlobular ducts. The epithelium of intralobular and interlobular ducts progresses from cuboidal to low columnar and contains sulfomucins. As the interlobular ducts approach the main pancreatic ducts, they develop an increasingly thick collagenous wall. The epithelium becomes columnar and the epithelial mucins are more abundant. Each main pancreatic duct receives numerous tributaries of interlobular ducts (Klimstra 1997).
Lacrimal Gland Insufficiency in Aqueous Deficiency Dry Eye Disease: Recent Advances in Pathogenesis, Diagnosis, and Treatment
Published in Seminars in Ophthalmology, 2022
Microscopically, the lacrimal gland is formed of acinar epithelial cells forming lobules draining into intralobular ducts. The ducts are lined by tubular columnar cell, surrounded by myoepithelial cells.39,40 The intralobular ducts further merge into interlobular ducts which are lined by cuboidal cells and open in the superior and inferior fornix as 3–12 excretory ductules.39–42 Recently, the role of columnar cells of ducts in the secretion of tears have also been found; however, this still requires further studies for confirmation.43 The intervening interstitial connective tissue contains lymphocytes, plasma cells, mucosa-associated lymphoid tissue, fibroblasts, blood vessels and nerve fibres.29,32,39 Accessory lacrimal glands are similar to the main lacrimal gland microscopically.
Histological and biochemical evaluation of the effects of silver nanoparticles (AgNps) versus titanium dioxide nanoparticles (TiO2NPs) on rat parotid gland
Published in Ultrastructural Pathology, 2023
Sara M. Abdel Aal, Maha Z. Mohammed, Abeer A. Abdelrahman, Walaa Samy, Ghadeer M. M. Abdelaal, Raghda H. Deraz, Shaimaa A. Abdelrahman
H & E-stained sections of the control group showed normal architecture of the parotid gland in the form of lobules separated by thin septa and excretory ducts. Each lobule was composed of a closely packed purely serous acini lined by cells with eosinophilic granular cytoplasm and basal rounded nuclei. The intralobular duct system showed intercalated and striated ducts Figure 2(a,b). Mallory trichrome stained sections showed few collagen fibers between the lobules, around interlobular ducts, and blood vessels Figure 2(c). Weak positive cytoplasmic immunoreaction for CD-68 in few inter-acinar cells Figure 2(d) and weak positive cytoplasmic immunoreaction for caspase-3 in few cells Figure 2(e).
Development of a catheter-based technique for endoluminal radiofrequency sealing of pancreatic duct
Published in International Journal of Hyperthermia, 2019
Elżbieta Ewertowska, Anna Andaluz, Xavier Moll, Adrià Aguilar, Felix Garcia, Dolors Fondevila, Rita Quesada, Macarena Trujillo, Fernando Burdío, Enrique Berjano
Figure 5 shows histological images of normal pancreatic tissue and pancreas after treatment. The histological study of the treated samples revealed complete acinar atrophy and that only the intralobular ducts remained after ductal ablation (Figure 5(D,E)). The epithelium of the interlobular and some of the intralobular ducts showed a metaplasia from columnar or cuboidal to squamous and was lost in other areas (Figure 5(F)). All the samples showed marked periductal and interlobular fibrosis (Figure 5(D–F)) and scattered inflammatory infiltrate (Figure 5(F)).