China
Africa
Explore chapters and articles related to this topic
Thyroidectomy
Published in R James A England, Eamon Shamil, Rajeev Mathew, Manohar Bance, Pavol Surda, Jemy Jose, Omar Hilmi, Adam J Donne, Scott-Brown's Essential Otorhinolaryngology, 2022
Surgical scars are a significant concern for patients. Of patients from a thyroid clinic who were surveyed, 71% preferred an extracervical scar given the choice, and results were independent of sex and skin colour.
Scar Care after Surgical Treatment in Oncology Patients
Published in Paloma Tejero, Hernán Pinto, Aesthetic Treatments for the Oncology Patient, 2020
There are certain factors that influence the wound healing process and the cosmetic result of scars. Identifying these factors, we can anticipate the available resources in order to achieve the best result. There is an important systemic involvement in all wound healing phases, and consequently, a correct result will not only depend on local factors.
Benign tumours, moles, birthmarks and cysts
Published in Ronald Marks, Richard Motley, Common Skin Diseases, 2019
A scar is a reparative response to injury of some kind, accidental or surgical, or tissue destruction from an inflammatory skin disorder, in which the tissue architecture cannot be entirely restored and the defect is made good with fibrous tissue. A hypertrophic scar is usually pink, smooth and variably raised (Fig. 14.31). The excess scar tissue generally flattens after some months or can be encouraged to do so with topical or intralesional corticosteroids and with an occlusive silicone dressing and/or firm pressure bandaging.
High-intensity focused ultrasound therapy for pediatric and adolescent vulvar lichen sclerosus
Published in International Journal of Hyperthermia, 2022
All patients successfully underwent HIFU therapy. The results pertaining to the treatment are shown in Table 2. The device output power in 26 (72.2%) patients was set at level 2, and in 10 (27.8%) patients it was set at Level 3. The sonication time was 20.3 ± 8.6 min, and the median treatment energy was 3579.0 J. A few blisters developed in eight (22.2%) patients, of which two patients developed superficial skin ulcers. About 1 week after the treatment, the six patients who had a few blisters in the vulvar treatment area improved after topical treatment with moist burn ointment without obvious pain, infection and scar formation. An 18-year-old patient was treated with output power Level 2 for 10 min and 15 s, with a total energy of 1393 J. On the seventh day of treatment, multiple ulcers and inflammatory exudation were found during the outpatient follow up review. The patient was given anti-infection treatment, moist burn ointment and epidermal growth factor, which were applied externally, and the wound healed 1 month later. Another 8-year-old child was treated with HIFU for 8 min with an energy of 1494 J. A few blisters appeared immediately after therapy. One week later, multiple superficial ulcers were seen in the treatment area. Mupirocin was given as a local anti-infection treatment. Moist burn ointment and epidermal growth factor were also applied. The wound healed within 1 month of treatment without scar formation.
TSG-6 Inhibits the Growth of Keloid Fibroblasts Via Mediating the TGF-β1/Smad Signaling Pathway
Published in Journal of Investigative Surgery, 2021
Xin-Yi Li, Xiao-Juan Weng, Xiao-Jing Li, Xiao-Yu Tian
Pathological scar proliferation is the result of excessive skin restoration after injury; it is mainly identified by fibroblasts hyperplasia and the accumulation of ECM components [24]. Keloids can invade adjacent tissues and destroy normal skin appendages and do not have the characteristic of self-restriction. Therefore, many researchers hold the opinion that keloids were benign fibrous tumors resulting from inappropriate proliferation and apoptosis [25]. Inhibiting the proliferation or promoting the apoptosis of fibroblasts is the key to the treatment of scars. In this study, we sought to ascertain whether TSG-6 antagonizes TGF-β1-mediated fibrotic responses in HKFs. We found that TSG-6 could inhibit the expression of related factors in the TGF-β1 pathway, such as the Smad2/3/4 complex, which is detrimental to fibroblast proliferation.
Immediate fat and nanofat-enriched fat grafting in breast reduction for scar management
Published in Journal of Plastic Surgery and Hand Surgery, 2021
Cemal Alper Kemaloğlu, İrfan Özyazgan, Zeynep Burçin Gönen
A scar is a sign of tissue repair that develops after surgery, injury, burns and cuts. Although scar formation is crucial for healing, it poses a major problem for patients due to the cellular and mechanical nature of the scar, creating cosmetic, psychological and functional limitations [4]. Thus, numerous measures have been reported, such as laser treatment, silicone sheets, topical creams and intralesional application of medical agents, to improve scar quality and decrease potentially related symptoms [5–9]. In recent decades, fat grafting has gained popularity for scar modulation. Previous studies have shown that fat grafting improves scar quality and provides good cosmetic results in patients with various scars developed due to trauma, surgery and burns [10–12]. This improvement may be attributed to adipose-derived stem cells (ADSCs) releasing several factors beneficial for wound healing and regeneration [13–15].