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Nonmelanocytic Lesions
Published in Ashfaq A Marghoob, Ralph Braun, Natalia Jaimes, Atlas of Dermoscopy, 2023
Constanza Riquelme-Mc Loughlin, Daniel Morgado-Carrasco, Susana Puig, Cristina Carrera
Poromas are benign tumors, but the structures and patterns they manifest are not reliable in differentiating them from malignant tumors such as porocarcinoma (Figure 6g.6). Thus, it is recommended that lesions suspicious for poroma undergo histopathology confirmation [7]. In addition, several cases of malignant transformation [10] and/or coexistence of poroma with porocarcinoma have been reported [1].
Malignant vascular, adnexal, and fibrous tissue tumors
Published in Iris Zalaudek, Giuseppe Argenziano, Jason Giacomel, Dermatoscopy of Non-Pigmented Skin Tumors, 2016
Aimilios Lallas, Elvira Moscarella
Porocarcinoma typically arises in association with a preexisting benign poroid tumor, usually on the lower extremities. It most commonly presents as a reddish ulcerated nodule, but it is characterized by a high degree of clinical variability. Dermoscopy reveals a polymorphous vascular pattern comprising dotted and linear irregular vessels, possibly in combination with ulceration (Figure 28.8).10â12
Primary eccrine porocarcinoma of the thumb with multiple metastases: a case report and review of the literature
Published in Case Reports in Plastic Surgery and Hand Surgery, 2019
Connor McGuire, Zahir Fadel, Osama Samargandi, Jason Williams
Follow up initially was unremarkable and the wound healed well. However, four months after the operation the patient had a CT scan demonstrating a seroma in the axilla that required drainage. Seven months after surgery, a suspicious lesion was identified in the scar of the right amputated thumb (Figures 3a,b). Subsequently, the new lesion was excised with clear margins after two operations and histologic examination was positive for recurrent porocarcinoma. During the second excision the plastic surgery team completed a transfer of the flexor pollicis longus tendon to the distal bone stump to help maintain some of the adduction strength of the thumb (Figures 4 a,b). In May of 2018 the patient presented with new subcutaneous lesions. Biopsies of the right chest wall, right anterior axillary line, and right radial wrist revealed metastatic porocarcinoma. The patient received radiation therapy to the right axillary bed. Subsequent discussions with medical and radiation oncology revealed the progressing difficulty of the situation- as metastatic porocarcinoma is so rare, there are few studies investigating treatment protocols. The conversation initially shifted from curative intent to improving quality of life, however after treatments with paclitaxel (175âmg/m2), carboplatin (area under the curve = 5), and intralesional interleukin 2 (IL-2) injections the metastases responded with near complete disappearance of the cutaneous lesions. After one year of follow-up the patient was still responding well to this maintenance treatment.