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The science of ageing
Published in Michael Parker, Charlie James, Fundamentals for Cosmetic Practice, 2022
Chemical peels are believed to work by initiating the repair mechanisms of the skin due to transient inflammation secondary to epidermolysis and, if deep, inflammation of the dermis itself. The peels can be broken down into three categories depending on the level of penetration (Table 5.2), which, in turn, depend on the substance used (and concentration), pH of the solution and the length of time the peel remains in contact with the skin.
Cosmetic dermatology
Published in Ronald Marks, Richard Motley, Common Skin Diseases, 2019
With this technique, acids are applied to the skin to create a superficial or partial thickness chemical injury. The treated skin separates after a few days as the underlying skin re-epithelializes. Chemical peels may be considered very superficial, superficial, medium or deep. Deep chemical peels are created with phenol-containing preparations and can produce a dramatic change in the appearance of the skin but they are not without hazards and require several weeks’ recovery. The pigmentary changes induced by a deep peel may cause concern. Superficial and very superficial chemical peels take 5–7 days for full effect, the changes to the skin surface immediately after treatment are mild and the improvement in skin surface is correspondingly mild, but these treatments may be repeated for increased effect. Superficial peels are primarily effective for dyschromia whereas medium depth peels will reduce wrinkles and deep peels will tighten the skin and reduce the appearance of scars.
Emergencies associated with cosmetological procedures
Published in Biju Vasudevan, Rajesh Verma, Dermatological Emergencies, 2019
Complications associated with chemical peels: Complications (Table 63.1) are usually minor and can be easily treated. Most of the complications occur due to improper patient selection or due to inadequate priming. Sometimes the priming agents are not withdrawn adequately before the peel, causing the skin to be dry and the peeling agent to penetrate deeper than indicated. Perioral and periorbital areas often have lines or creases where the peel agent can accumulate and avoid being neutralized adequately and cause a chemical burn (Figure 63.1) or a scab that is discovered the next day [1]. Usually these are superficial scabs and they resolve without incident. However, if there is a social event on the next few days, it needs to be treated as an emergency.
Effect of mesotherapy with nanochip in the treatment of facial rejuvenation
Published in Journal of Cosmetic and Laser Therapy, 2020
Lingling Hu, Kejia Zhao, Wei Min Song
This was a single-center prospective pilot study. Twenty-four women (range 30–52 years, mean age 41) with clinical signs of moderate photoaging were enrolled in this trial. The protocol was approved by our local institutional review board. Inclusion criteria were as follows: female and male gender, age ranging from 30 to 65 years, and presence of physical signs of moderate photoaging on facial skin. Exclusion criteria were superficial chemical peels performed within 4 weeks, history of allergic and/or irritant contact dermatitis, bleeding diathesis, photo-allergy and/or unprotected sun exposure systemic diseases, psychiatric illness, and pregnancy, or breastfeeding females. Informed consent from all participants was obtained.
Effective treatment of disseminated superficial actinic porokeratosis with chemical peels – customary treatment for a rare disease
Published in Journal of Dermatological Treatment, 2020
Berenice M. Lang, Adriane Peveling-Oberhag, Sebastian Zimmer, Joanna Wegner, Anna Sohn, Stephan Grabbe, Petra Staubach
To the best of our knowledge, no report is published for chemical peels as treatment option against porokeratosis to date. The mode of operation of chemical peels is more than just ablation of epithelia. Glycolic and salicylic acid have keratolytic and anti-inflammatory characteristics and also induce new formation of collagen. Above that, a tumor protective effect was proven in mice for both substances especially for UV-induced tumors which is a relevant fact for DSAP patients. Furthermore, chemical peels are fairly easy to apply in daily dermatological practice and come along with good tolerability and only mild side effects (8,9).
Clinical and dermoscopic evaluation of combined (salicylic acid 20% and azelaic acid 20%) versus trichloroacetic acid 25% chemical peel in acne: an RCT
Published in Journal of Dermatological Treatment, 2019
Rania Abdel Hay, Rehab Hegazy, Mohamed Abdel Hady, Noha Saleh
Acne and acne-prone oily skin are reasonably well-accepted indications for chemical peeling. Being quite safe, chemical peels are useful both as an adjunct to medical therapy and to help maintain good results after medical therapy can be tapered or is no longer necessary. Chemical peels may be an alternative in the unusual circumstance where the patient cannot tolerate acne medications (1). For better results in acne treatment, multiple treatments are needed as the results are not long-lasting (2).