China
Africa
Explore chapters and articles related to this topic
How to prevent and treat chemotherapy-induced nail abnormalities
Published in Robert Baran, Dimitris Rigopoulos, Chander Grover, Eckart Haneke, Nail Therapies, 2021
Most anticancer drug-induced nail lesions do not require treatment as they are asymptomatic. Moreover, at the time of diagnosis they reflect the past effects of anticancer drugs on the matrix. Thus, changes like Beau’s lines, onycholysis and pigmentation will disappear with nail growth and discontinuation of treatment. The nail will return to a normal appearance after its complete growth in 4 to 6 months for hands and 12 to 18 months for toes.
Hair and nail disorders
Published in Rashmi Sarkar, Anupam Das, Sumit Sethi, Concise Dermatology, 2021
Onycholysis due to thyrotoxicosis has already been mentioned. In hypoalbuminaemia (as in severe liver disease), the lunulae may be lost and the nail plate turns a milky white. Beau’s lines are horizontal ridges due to a sudden severe illness, trauma, and/or blood loss and presumably have the same significance as telogen effluvium. They grow outwards and are eventually lost.
Disorders of hair and nails
Published in Ronald Marks, Richard Motley, Common Skin Diseases, 2019
Onycholysis due to thyrotoxicosis has already been mentioned. In hypoalbuminaemia (as in severe liver disease), the lunulae may be lost and the nail plate turns a milky white. Beau’s lines are horizontal ridges due to a sudden severe illness, trauma and/or blood loss and presumably have the same significance as telogen effluvium. They grow outwards and are eventually lost.
Optimal diagnosis and management of common nail disorders
Published in Annals of Medicine, 2022
Beau’s lines, onychomadesis and retronychia are three nail disorders that are thought to lie on a continuum and share a common pathophysiology. For all three conditions, there is an insult to the nail matrix, which slows or halts nail plate production. Despite this shared pathophysiology, all three disorders most often present independently, but two to three can also occur concurrently [114]. Medication use, infection, systemic disease and trauma are common aetiologies [115]. Extent of trauma or severity of systemic insult to the nail matrix, duration of nail growth cessation and direction of growth are determinants of the clinical presentation. Differentiation of these three nail disorders from each other and from other nail conditions can expedite treatment and improve prognosis.
Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression with Alopecia Areata in Males: A Case–control Study
Published in Immunological Investigations, 2020
Eman A. Toraih, Hatem M Ameen, Mohammad H. Hussein, Ahmed A. Youssef Elabd, Abeer M. Mohamed, Abdelhady Ragab Abdel-Gawad, Manal S. Fawzy
Total body skin examination was performed to confirm the diagnosis of AA and concurrent dermatological conditions (Figure 2). Scalp examination was performed to identify the clinical pattern and extent of alopecia. Nail examination was done to search for any nail abnormalities such as nail pitting, Beau’s lines or red lunula. AA Patients were evaluated for the presence of other features of APECED syndrome via the existence of at least two of the following triad: autoimmune adrenal failure (Addison’s disease), hypoparathyroidism and chronic mucocutaneous candidiasis. In addition to other endocrine conditions (testicular failure, diabetes mellitus, hypothyroidism), skin disorders (rash with fever, vitiligo), eye disorders (keratoconjunctivitis), and gastrointestinal disorders (pernicious anemia, chronic diarrhea, hepatitis, severe obstipation).
Association of Rs231775 Genetic Variant of Cytotoxic T-lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case–Control Study
Published in Immunological Investigations, 2021
Nader Ali Ismail, Eman Ali Toraih, Hatem Mohamed Ameen, Amal Hussein Ahmed Gomaa, Radwa El- Sayed Mahmoud Marie
All patients had sudden, progressive, scalp hair loss. Only patchy and ophiasis manifestations were observed; 77 patients had patchy lesion while 10 patients had ophiasis and 6 patients had both lesions. None had alopecia totalis or universalis. They had experienced AA for a mean duration of 4.46 ± 9.1 months. Nail changes were obvious in 32.3% of cases including pitting and Beau’s lines (Table 1).