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The Non-Prescription Products – Market-Profits and Public Health in Conflict
Published in Mickey C. Smith, E.M. (Mick) Kolassa, Walter Steven Pray, Government, Big Pharma, and the People, 2020
Manufacturers also market numerous medical devices that do not contain pharmacologically active ingredients, but they also claim Health benefits. Laws are in place to control these products. Some medical devices are safe (dental floss), but others carry known dangerous devices (ear candles).
Individualized Prevention
Published in Lars Granath, William D. McHugh, Systematized Prevention of Oral Disease: Theory and Practice, 2019
Lars Granath, William D. McHugh
It has been shown that use of dental floss in young individuals can remove a substantial part of the interproximal plaque which remains after ordinary toothbrushing.30 It would be reasonable to assume that reduction of the amount of plaque interproximally would lead to inhibition of caries, but this is not necessarily so. In cases of normal tooth contacts and a normally situated gingival margin, the interproximal plaque is relatively thin below the contact point or area where caries starts. It has been stressed that unless all plaque is removed, the ecology of the remaining plaque with its mixture of viable and nonviable bacteria will be disturbed at the particular site, and the measure might lead to an effect which is the opposite of that intended.
The Cohort Study: Rates – The Concept of Bias
Published in Johan Giesecke, Modern Infectious Disease Epidemiology, 2017
Another principal conceptual difference concerns the measures of strength of association in the two types of studies: the ORs and the RRs. As was pointed out in Chapter 5, an OR does not have any directly interpretable meaning; it just tells us how strongly an exposure and an outcome seem to be related. In the example with dental floss above, a case control study might reveal a very strong and statistically significant relationship between floss usage and endocarditis. But this OR would not tell us what we really want to know: What is my risk of developing endocarditis if I use dental floss regularly for, say, 30 years? To answer this question, we need a study that could measure the risks, and we are left with the option of an impossible cohort study.
The effect of leukocyte-platelet-rich fibrin on bone morphogenetic protein-2 and insulin-like growth factor-1 levels in patients with chronic periodontitis: a randomized split mouth clinical trail
Published in Growth Factors, 2018
Alper Kizildağ, Yasin Çiçek, Taner Arabaci, Oğuz Köse
An antibiotic (amoxicillin and clavulanic acid) and an analgesic (naproxen sodium) were prescribed to prevent the inflammation and given two times per day for seven days, along with chlorhexidine digluconate rinses (0.12%) twice daily for two weeks. After operation, the silk suture and periodontal dressings were removed after 2 weeks, and the patients were told to brush the surgical area gently. The patients were instructed to use the dental floss/interproximal toothbrush. All of the subjects were recalled once every two weeks for 2 months after surgery. The patients were then examined monthly from the third month to the sixth month. Subgingival treatment was not applied at any of these controls.
Oral health behaviours in 12-year-olds. Association with caries and characteristics of the children?
Published in Acta Odontologica Scandinavica, 2022
Christine Sophie Baumgartner, Nina Johanne Wang, Tove Irene Wigen
One-third of the children in the present study reported flossing more than once a week. Few studies have reported the use of dental floss in teenagers and the frequency of use varies [10,11,13]. The results showed no association between flossing and having caries at 12-year of age when controlled for the other oral health behaviours and characteristics of the children. It has been shown that the use of dental floss or interdental brushes in addition to tooth brushing may reduce interproximal gingivitis or plaque more than tooth brushing alone, but the evidence for use of dental floss to prevent caries development is limited [12].
High-throughput DNA sequencing of microbiota at interproximal sites
Published in Journal of Oral Microbiology, 2020
Miguel Carda-Diéguez, Luis Alberto Bravo-González, Isabel María Morata, Ascensión Vicente, Alex Mira
Dental plaque was sampled from the interproximal region with sterile dental floss reaching the bottom of the groove, on mesial and distal sides between upper left first and second premolars (1.4 and 1.5 teeth) and repeated again in the same patients after 1 month [13]. Vestibular (buccal) and Lingual (palatine) samples were obtained with an autoclaved spoon excavator at tooth 1.4 [5]. In both cases, the obtained plaque was placed in sterile 1.5 ml tubes with saline solution and kept at – 20ºC until DNA was extracted.