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Biobased Products for Viral Diseases
Published in Mahendra Rai, Chistiane M. Feitosa, Eco-Friendly Biobased Products Used in Microbial Diseases, 2022
Gleice Ribeiro Orasmo, Giovanna Morghanna Barbosa do Nascimento, Maria Gabrielly de Alcântara Oliveira, Jéssica Missilany da Costa
Houttuynia cordata T. also known as fish mint, fish leaf, fish grass, Chinese lizard tail, among other names. It is an aromatic medicinal plant native to Southeast Asia mainly confined to a humid environment. Studies have shown that H. cordata T. ethyl acetate extract is effective in inhibiting dengue virus infectivity (Xie et al. 2013; Chiow et al. 2016). The H. cordata T. extract also inhibited avian infectious bronchitis virus (Yin et al. 2011) and influenza A (Choi et al. 2009) in the early stages of infection.
Lasia spinosa: Wild Nutraceutical for Formulation of Future Drugs
Published in Jayanta Kumar Patra, Gitishree Das, Sanjeet Kumar, Hrudayanath Thatoi, Ethnopharmacology and Biodiversity of Medicinal Plants, 2019
Sabeela Beevi Ummalyma, Rajkumari Supriya Devi
The leaves of Houttuynia cordata, Psidium guajava, and stalk of Lasia spinosa (L.) Thwaites possess potential anticestodal efficiency as evidenced by means of mortality rate of R. echinobothrida which ranged from 1–4 hrs exposed with 5–40 mg/ml of extract. The leaves of Lasia spinosa (L.) Thwaites along with other plant such as Clerodendrum colebrookianum, Centella asiatica showed moderate activity while Lasia spinosa stem with other plants extract of Cinnamomum cassia, Curcuma longa, and Aloe vera showed negative effect on anticestodal activity (Temjenmongla et al., 2005). The extracts (methanol) of Lasia spinosa (L.) Thwaites leaf used against Pheretima posthuma various concentrations varied from 25, 50 and 100 mg/ml used for the determination of paralysis and time for death of worms. The results showed that extract has considerable effect on paralysis and death of worms with 100 mg/ml in comparison with standard albendazole (Goshwami et al., 2013). The efficacy of Lasia spinosa (L.) Thwaites leaf extract against all the three life cycle stages including adult, larval form and encysted muscle larvae of Trichinella spiralis. The potential of leaf extract as significant anthelmintic properties against the larva and adult worm Trichinella spiralis less sensitive in the case of encysted larva (Yadav et al., 2011).
THE THEORY AND APPLICATION OF FUNCTIONAL FOOD IN CHINESE MEDICINE
Published in Kevin Chan, Henry Lee, The Way Forward for Chinese Medicine, 2001
Long history and rich experience of traditional Chinese medicine in food therapy provides us with a number of traditional functional foods e.g., Herba Houttuyniae Houttuynia cordata Thunb., and Vaccinium bracteatum (Vaccinium fragile Franch.). With the development of advanced technology, a new generation of Chinese functional food is emerging. In addition to the human and animal testing for the effects of functional food on the body regulation, the structure and quantity of active ingredients of some functional food are also determined. The new generation functional food will have higher quality and popularity in international markets.
Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: an 8-week, double-blinded, randomized, controlled trial
Published in Journal of Dermatological Treatment, 2021
Ji Hoon Yang, Eun Ju Hwang, Jungyoon Moon, Ji Young Yoon, Ji Won Kim, Sungjun Choi, Soo Ick Cho, Dae Hun Suh
Lithospermum officinale, Tribulus terrestris L., and Houttuynia cordata Thunb are the herbs that have been used in East Asia since ancient times and nowadays they are often included in cosmetics as natural substances. Phenolic acid which is included in Lithospermum officinale has potent anti-inflammatory and antioxidant capacity by inhibiting lipoxygenase activity (7). Lee et al. have demonstrated that Tribulus terrestris L. can reduce the expression of LPS-induced inflammatory cytokines, including IL-6 and TNF-α which are important molecules in the inflammatory pathway of acne (8). Also, through many studies, Houttuynia cordata Thunb was found to reduce inflammatory cytokines by inhibiting NF-κB pathways (9). As these herb extracts can inhibit various inflammatory cytokines which are important in the pathogenesis of acne, compound of these herbal extracts may have better therapeutic potential than individual ingredient.
Effect of Heat Treatment on the Anticancer Activity of Houttuynia cordata Thunb Aerial Stem Extract in Human Gastric Cancer SGC-7901 Cells
Published in Nutrition and Cancer, 2021
Jinjuan Liu, Xinting Zhu, Daning Yang, Rongpeng Li, Jihong Jiang
Houttuynia cordata Thunb (HCT), as a traditional Chinese herb medicine, has been used as food in Asia for a long time. Although HCT was reported to be active against tumors, each part of HCT and the diet style on their anticancer has never been well examined before. In the present study, the anti- cancer activity of each part of HCT (heated and not heated) was investigated in HepG2, SGC-7901, NCI-460 and HO-8910 cells. Results showed that each part of HCT (AS, SS, L) all have anticancer activity in a dose-dependent manner (Fig. 1). Interestingly, the activity of extract after boiling for 30 s was higher than not heated extract, except SS. The inhibit activity of HAS is 4-7 times as great high as NAS (p < 0.01) in the four cell lines, especially in human gastric carcinoma SGC-7901cell. It suggested that the anticancer activity of HCT was different from diet style.
Inhibiting the PI3K/AKT/mTOR signalling pathway with copper oxide nanoparticles from Houttuynia cordata plant: attenuating the proliferation of cervical cancer cells
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2021
Hongmin Chen, Xiaojie Feng, Ling Gao, Suresh Mickymaray, Anand Paramasivam, Faiz Abdulaziz Alfaiz, Hussain A. Almasmoum, Mazen M. Ghaith, Riyad A. Almaimani, Ibrahim Abdel Aziz Ibrahim
Houttuynia cordata is a perennial herb belongs to the family of Saururaceae is an indigenous species of Asia, Japan and China. It is an inhabitant of moist environment and utilized as both edible food and also as a medicine for various ailments [11]. H. cordata proven to possess various pharmacological properties such as antidiabetic, antioxidant, antiinflammatory, antihypertension, adjuvanticity and antiviral activities [12]. It is also prescribed to respiratory diseases such as pneumonia, severe acute respiratory syndrome, etc. [13–15]. Nanotechnology is a boon for various fields especially in the field of medicine; it plays a remarkable role. Hence, researchers were focussed on utilizing nanotechnology to formulate a drug with traditional herbal medicine since nanodrugs are more cite targeted and it also increases the efficacy of traditional medicine, Therefore in the current study, we formulated a copper nanodrug with the plant extract of H. cordata (Hc-CuONPs) and assessed its efficacy against cervical cancer cell line.