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Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Cinnamomum cassia (Nees & T. Nees) J. Presl, also called Chinese cinnamon, is a medium-sized (10–15 meter tall) evergreen tree, with greyish bark and hard elongated leaves that are 10–15 cm long, belonging to the Lauraceae. It is native to China and is widely distributed in China, Vietnam, Sri Lanka, Madagascar, Seychelles and India. The tree is cultivated in China, Laos, Thailand, Vietnam, Indonesia and Malaysia. It is one of the most important economic plant resources in tropical and subtropical areas (18).
Assyria
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
The root of the cassia plant (Cinnamomum cassia) was applied to the uterus ‘with five other drugs’ for the condition. The BHP (1983 p. 69) classifies Cinnamomum cassia as an antimicrobial. Could the Ancient Assyrians have understood that prolonged membrane rupture could lead to sepsis in utero?.
Herbs with Antidepressant Effects
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
Cinnamon is a spice obtained from the inner bark of several tree species from the genus Cinnamomum. Ceylon cinnamon (the source of its Latin name, zeylanicum) or “true cinnamon” is indigenous to Sri Lanka and southern parts of India. There is also Cinnamomum cassia, known as Chinese cinnamon. Cinnamon in its various forms was known by the ancients and highly prized. It has been used primarily as a food spice, but also has a long history of use as a medicinal herb. In Ayurvedic Medicine, cinnamon is considered a remedy for respiratory, digestive, and gynaecological ailments. Modern research has established that cinnamon has properties including anti-microbial, hypoglycemic, antihypertensive, anti-oxidant, and free-radical scavenging properties, inhibition of tau aggregation, and anti-nociception, anti-inflammatory, and hepato-protective effects.1 Among the phytochemicals in the various cinnamons are cinnamaldehyde – the predominant molecule – as well as cinnamic acid, cinnamyl alcohol, coumarin, eugenol, linalool, benzyl benzoate, and δ-cadinene.2 A significant difference between “true” Cinnamon and Chinese Cinnamon is that Chinese cinnamon can contain much higher, even potentially dangerous, levels of coumarin. As is commonly seen, the species of the genus Cinnamomum will here be generally referred to by the common name cinnamon.
Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways
Published in Pharmaceutical Biology, 2023
Ting Chen, Shengchuan Bao, Juan Chen, Jiaxiang Zhang, Hailiang Wei, Xin Hu, Yan Liang, Jingtao Li, Shuguang Yan
Xiaojianzhong decoction (XJZD), a famous Chinese herbal formula, is commonly used with remarkable clinical efficacy in the treatment of gastritis, gastric ulcer, ulcerative colitis, irritable bowel syndrome and other digestive diseases. The formula for XJZD consists of six herbs: Cinnamomum cassia Presl. (Lauraceae), Paeonia lactiflora Pall. (Paeoniaceae), Zingiber officinale Rosc. (Zingiberaceae), Glycyrrhiza uralensis Fisch. (Leguminosae), Ziziphus jujuba Mill. (Rhamnaceae) and Saccharum granorum (Maltose). Modern pharmacological studies have confirmed that ginger can effectively promote the synthesis of gastric mucosa, attenuate the digestive effect of pepsin, and exert an effective protective role on gastric mucosa (Haniadka et al. 2013). Cinnamaldehyde, the main component of Cinnamomum cassia, has antiulcer properties and can repair mucosal damage (Dorri et al. 2018). Paeoniflorin, the main component of Paeonia lactiflora, has anti-inflammatory and antioxidant activities and can reduce cell damage (Zhang et al. 2013). Licorice flavonoids, the main component of Glycyrrhiza uralensis, play a role in the treatment of gastric ulcers by regulating inflammatory mediators and amino acid metabolism (Yang et al. 2017). These findings suggest that XJZD may have the effect of preventing and treating gastric mucosal injury.
In vitro inhibition of food borne mutagens induced mutagenicity by cinnamon (Cinnamomum cassia) bark extract
Published in Drug and Chemical Toxicology, 2018
Spices and herbs have been used for years to enhance the flavor and aroma of foods. The genus Cinnamomum comprises about 250 species which are distributed in Asia and Australia. Cinnamomum cassia originated from Sri Lanka (Radhakrishnan et al.1992, Jayaprakasha et al.2003) and is used in culinary preparations. Among the various medicinal properties reported, cinnamon is additionally used for treating common cold, for improving glucose metabolism in diabetics (Ping et al.2010, Kim et al.2006), useful as antidiarrheal (Kayande et al.2014), and antimicrobial agent (Singh et al.2007), and for inhibiting various cell lines (Schoene et al.2005, Kwon et al.2009). Cinnamons are rich in flavonoids, which are potent antioxidants (Singh et al.2007). The main constituent of cinnamon bark oil is cinnamaldehyde (CLD) (Mallavarapu et al.1995).
Antibacterial effects of 18 medicinal plants used by the Khyang tribe in Bangladesh
Published in Pharmaceutical Biology, 2018
Md Shahadat Hossan, Hassan Jindal, Sarah Maisha, Chandramathi Samudi Raju, Shamala Devi Sekaran, Veeranoot Nissapatorn, Fatima Kaharudin, Lim Su Yi, Teng Jin Khoo, Mohammed Rahmatullah, Christophe Wiart
Over the past few decades, there has been a dramatic decrease in the number of new antibiotic approved by the FDA. MRSA is a cause for concern due to the small number of antibiotics effective against this organism and resistance associated with their uses. The development of resistant-modifying agents could be a supplemental strategy to overcome resistance. The current result shows that Cinnamomum cassia has a broad-spectrum antibacterial activity. From this plant, cinnamaldehyde is a resistant-modifying agent that decreases the resistance of MRSA to vancomycin. Our study provides evidence that the medicinal plants in Bangladesh have high potential for the development of plant-based material to improve the current treatment strategies for bacterial infections.