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Animal Source Foods
Published in Chuong Pham-Huy, Bruno Pham Huy, Food and Lifestyle in Health and Disease, 2022
Chuong Pham-Huy, Bruno Pham Huy
Propolis, generally known as the ‘bee glue’, is a resinous mixture produced by honeybees from different leaf and flower buds, stems, and bark cracks of numerous species of plants (143–144). Bees use it mainly as a sealant and a disinfecting material for the reconstruction of the beehive. It is also used for smoothing the inner surface of the beehive, retaining the hive’s internal temperature (35°C), and preventing weathering and invasion by predators. Furthermore, propolis hardens the cell wall and contributes to an aseptic internal environment. Propolis generally becomes soft and sticky upon heating (143–144). Raw propolis contains 50–60% resins and balms (including phenolic compounds), 30–40% waxes and fatty acids, 5–10% essential oils, 5% pollen, and about 5% other substances including amino acids, micronutrients, and vitamins (B1, B2, B6, C, and E) (143–144). In addition, more than 300 compounds belonging to polyphenols, terpenoids, steroids, sugars, amino acids, and others have been identified in propolis. Propolis and its extracts have numerous applications in treating various diseases due to its antiseptic, anti-inflammatory, antioxidant, antibacterial, antimycotic, antifungal, antiulcer, anticancer, and immunomodulatory properties as well as neuroprotective effects (143–144).
Monographs of fragrance chemicals and extracts that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Of 21 patients allergic to propolis, 19 (90%) co-reacted to MP 25% pet. (156). Conversely, of 11 patients positive to MP who had never come into contact with propolis, 5 (45%) also reacted to propolis (156). Of 7 patients reacting to propolis, 6 (86%) co-reacted to MP (164). Of 102 patients allergic to MP, 9 co-reacted to propolis (13). Chemicals present in both propolis and Myroxylon pereirae include benzoic acid, benzyl alcohol, benzyl benzoate, benzyl caffeate, benzyl cinnamate, benzyl ferulate, benzyl isoferulate, caffeic acid, cinnamic acid, cinnamyl alcohol, coniferyl benzoate, farnesol, nerolidol and vanillin (119).
Lipid-Based Nanoparticles: SLN, NLC, and MAD
Published in Madhu Gupta, Durgesh Nandini Chauhan, Vikas Sharma, Nagendra Singh Chauhan, Novel Drug Delivery Systems for Phytoconstituents, 2020
Rita Cortesi, Paolo Mariani, Markus Drechsler, Elisabetta Esposito
Among natural compounds with antimicrobial activity, propolis can be considered. Indeed, propolis possesses many pharmaceutical properties (Henshaw et al., 2014). Propolis is a natural complex admixture of substances of different sources gathered and elaborated by bees (Apis mellifera L.) during their activities (Burdock, 1998, Marcucci, 1995). The main dosage form of propolis used on therapeutics is the ethanolic extract that, during preparation, forms residues (i.e., by-product or waste material).
Effect of in vitro simulated digestion on the anti-Helicobacter Pylori activity of different Propolis extracts
Published in Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Paolo Governa, Giulia Romagnoli, Paola Albanese, Federico Rossi, Fabrizio Manetti, Marco Biagi
Traditionally, propolis has been used for centuries as an antimicrobial agent.38 More recently, indeed, this activity has been demonstrated in vitro, in vivo, and in clinical trials as well, against Gram-positive and Gram-negative bacteria, including drug-resistant species, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and several Streptococcus strains, with minimum inhibitory concentration (MIC) varying based on the chemical composition39,40 Antifungal activity was also reported against different Candida species.41 The most widely accepted antimicrobial mechanism of action of propolis is related to its effect on membrane permeability, which may lead to cell lysis and may participate in reducing the development of resistance to antibiotic and antifungal drugs.42 Also, inhibition of bacterial RNA-polymerase was observed for some of the propolis constituents.43
Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica
Published in Toxin Reviews, 2023
T. M. Cantero, P. I. Silva Junior, G. Negri, R. M. Nascimento, R. Z. Mendonça
Propolis is produced with the resin that bees collect from the cracks in the bark and leaf buds of different trees, including different species of poplars, conifers (pines and cypress), birches, alders, willows, palms, chestnuts, eucalyptus, acacia, Clusia spp., Baccharis dracunculifolia DC, Dalbergia ecastaphyllum, among others (Pasupuleti et al. 2017, Kocot et al. 2018, Anjum et al. 2019, Šturm and Nataša Poklar Ulrih 2020). The products produced by stingless bee are promising sources of biologically active compounds, because in the tropical and subtropical regions exist a rich vegetation that can be used as resin source for production of propolis, geopropolis and honey (Al-Hatamleh et al. 2020). Stingless bee honey exhibited antimicrobial activity against gram positive bacteria: Micrococcus luteus, Bacillus brevis, B. megaterium and B. subtilis, as well as gram negative bacteria: Escherichia coli and Pseudomonas syringae (Al-Hatamleh et al. 2020). Some stingless bee species produce geopropolis, which contains soil into resinous material (Pereira et al. 2020).
Oral Propolis, Nutritional Status and Quality of Life with Chemotherapy for Breast Cancer: A Randomized, Double-Blind Clinical Trial
Published in Nutrition and Cancer, 2022
Seyed Hossein Davoodi, Vahid Yousefinejad, Bayazid Ghaderi, Mohammad Esmail Akbari, Shoaleh Darvishi, Yadollah Mehrabi, Nazila Darvishi
The above treatments, in addition to preventing loss of appetite and increasing the intake of food, should be safe, without side-effects, and tolerable to the patients. In our study, propolis was well tolerated in all the patients without adverse side effects. The patients who were excluded from the interventional group were due to a lack of regular use and unwillingness to continue to collaborate with the researchers. Propolis has other benefits for patients. Piredda et al. (2017) showed that propolis could be effective in preventing oral chemo-induced mucositis in patients with breast cancer (41). In another study, the beneficial effects of the oral administration of propolis on serum antioxidant capacity and improved absorption of iron from the digestive tract and hemoglobin regimen have been shown (42).