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Cataracts (Prevention)
Published in Charles Theisler, Adjuvant Medical Care, 2023
Lutein: Some studies suggest that eating higher amounts of lutein might decrease the risk of developing cataracts. Also, early previous studies indicate that taking lutein three times weekly for up to two years can improve vision in elderly people with cataracts.3
Nutraceuticals and Brain Disorders
Published in Debarshi Kar Mahapatra, Cristóbal Noé Aguilar, A. K. Haghi, Applied Pharmaceutical Practice and Nutraceuticals, 2021
Akshada Atul Bakliwal, Vijay Sharadkumar Chudiwal, Swati Gokul Talele
Lutein is one of the most significant carotenoids found in numerous leafy foods like mangoes, corn, sweet potatoes, carrots, squash, tomatoes, and so forth. Lutein dipalmitate is found in the plant Heleniumautumnale. Lutein, otherwise called helenien, is utilized for the treatment of visual issues. Zeaxanthin is utilized in customary Chinese medication principally for the treatment of visual issues. Nourishment wellsprings of zeaxanthin incorporate corn, egg yolk, green vegetables, and natural products, for example, broccoli, green beans, green peas, Brussels sprouts, cabbage, kale, collard greens, spinach, lettuce, kiwi, and honeydew. Lutein and zeaxanthin are likewise found in weeds, green growth, and the petals of many yellow blossoms. In green vegetables, foods grown from the ground yolk, lutein, and zeaxanthin exist in nonesterified structures.
Nutraceutical Bioactives
Published in Raj K. Keservani, Anil K. Sharma, Rajesh K. Kesharwani, Nutraceuticals and Dietary Supplements, 2020
Andrew G. Mtewa, Kennedy J. Ngwira, Stephen Lutoti, Davies Mweta, Patrick E. Ogwang, Duncan C. Sesaazi
Carotenoid-rich plants like tomatoes and carrots among others are significant natural plants that protect us against diseases. Lycopene and lutein are the most important and effective antioxidant carotenoids active against most diseases (Radhika et al., 2011). Lutein has been reported active against breast, lung, and cervical cancers and also has protective effects on muscular degeneration that is age dependent. Lutein is mostly found in green vegetables.
Changes in Aqueous Humor Lutein Levels of Patients with Cataracts after a 6-Week Course of Lutein-Containing Antioxidant Supplementation
Published in Current Eye Research, 2022
Rijo Hayashi, Shimmin Hayashi, Shigeki Machida
Among the carotenoids, only lutein, zeaxanthin, and their metabolites have been reported to be present in human ocular tissues, such as the retina9,10 and lens.11 Additionally, the intake of lutein has been reported to be advantageous in other studies, since it helps to increase macular pigment density12–14 and decrease the potential problems associated with age-related macular degeneration.15,16 Several epidemiologic studies have also reported that the intake of lutein was associated with decreases in the risk of cataract formation.17–20 However, there are other studies that have not reported the same results.21–24 A review of previous epidemiologic reports found that some of these studies were cross-sectional22,23 and simultaneously investigated the serum lutein levels and cataract severity. The lutein intake amounts in the previous studies also varied. Perhaps more importantly, the population evaluated in the majority of the previous studies varied from study to study. Moreover, confounding factors, such as genes, nutrient intake, and ultraviolet irradiation exposure, could additionally interfere with these assessments. Thus, by measuring the changes in the same person before and after the intake of supplements, which contain consistent amounts of nutrients, this might more accurately assess the actual effects of the antioxidant nutrients.
Traditional green leafy vegetables as underutilised sources of micronutrients in a rural farming community in south-west Nigeria I: estimation of vitamin C, carotenoids and mineral contents
Published in South African Journal of Clinical Nutrition, 2021
Shirley Isibhakhomen Ejoh, Faustina Dufie Wireko-Manu, David Page, Catherine MGC Renard
To the best of our knowledge, this study is the first report of lutein content of 16 TGLVs found in south-west Nigeria. There is a dearth of reports on the lutein content of TGLVs in Nigeria. TGLVs were found to be rich in lutein and with generally higher values than in literature reports for similar vegetables.21,22V. amygdalina stood out as having the highest lutein content. Lutein has been reported as the main carotenoid in the green vegetables.16 Given the high lutein content of most of the TGLVs, promoting their consumption could enhance lutein intake of consumers. This may be important where eye disease concerns exist,23 such as age-related macular diseases (AMDs) that have been related to lutein consumption,24 evidence of which is beyond the scope of the present study.
Preparation and characterization of lutein loaded folate conjugated polymeric nanoparticles
Published in Journal of Microencapsulation, 2020
Pradeep Kumar Bolla, Vrinda Gote, Mahima Singh, Venkata Kashyap Yellepeddi, Manan Patel, Dhananjay Pal, Xiaoming Gong, Devaraj Sambalingam, Jwala Renukuntla
One such promising therapeutic agent is Lutein. In 2017, a study evaluated the role of lutein as a neuroprotective agent in a rat model of neonatal hypoxic–ischaemic brain injury. Results from this study had proven that there was significant reduction of histological brain injury scores, inflammatory mediators, and hypoxia-inducible proteins such as HIF-1α with lutein treatment. Also, its oral supplementation to rats resulted in the selective accumulation of lutein in neonatal rat brains through breast milk (Foster et al.2017, Gong et al.2017). Lutein is a dihydroxy xanthophyll carotenoid available abundantly from green leafy vegetables, fruits, flowers, egg yolk, etc. (Li et al.2009, Hu et al.2012). As animals/humans cannot synthesise lutein, it must be obtained from diet. The neuroprotective effects of Lutein are attributed to its anti-inflammatory and anti-oxidant properties (Li et al.2009, Lim et al.2016, do Prado Silva et al.2017). Unfortunately, lutein has poor bioavailability due to high lipophilicity (LogP: 7.9) and poor aqueous solubility (Ozawa et al.2012, Drug Bank 2020). Therefore, there is an unmet need for developing a new formulation of lutein with enhanced bioavailability.