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Nutrition, the Mediterranean Diet and Selected Supplements for the Prevention and Treatment of Coronary Heart Disease
Published in Stephen T. Sinatra, Mark C. Houston, Nutritional and Integrative Strategies in Cardiovascular Medicine, 2022
Caloric restriction refers to reduction of energy intake at the individualized level that is sufficient to maintain a slightly low to normal body weight (i.e. BMI < 21 kg/m2) without causing malnutrition [154]. Findings from long-term calorie restriction in animal models have revealed improvements in metabolic health, offsetting chronic disease and consequently extending life span [155].
Personalized Nutrition in Children with Crohn Disease
Published in Nilanjana Maulik, Personalized Nutrition as Medical Therapy for High-Risk Diseases, 2020
In addition to effects upon weight gain, many children may also have impaired linear growth (Gasparetto and Guariso 2014; Walters and Griffiths 2009). This again is predominantly mediated by the effects of pro-inflammatory cytokines (especially interleukin 6) upon growth plates and upon the production of insulin-like growth factor 1. Caloric restriction (malnutrition) may also contribute to this adverse effect.
Personal Weight Loss Strategies in Obesity
Published in Emily Crews Splane, Neil E. Rowland, Anaya Mitra, Psychology of Eating, 2019
Emily Crews Splane, Neil E. Rowland, Anaya Mitra
As previously discussed, lasting weight loss requires caloric restriction. This means a combination of eating less food and probably eating food that is less delicious. Ideally, this difficult dietary change should be combined with regular exercise and must be continued for the rest of one’s life. The severity of the overnutrition problem combined with the unpalatable nature of the solution create an environment of hopelessness, delusion, and desperation; an environment where the promise of the next new diet or exercise intervention thrive.
Weight status is associated with clinical characteristics among individuals with bulimia nervosa
Published in Eating Disorders, 2023
Paakhi Srivastava, Emily K. Presseller, Joanna Y. Chen, Kelsey E. Clark, Rowan A. Hunt, Olivia M. Clancy, Stephanie Manasse, Adrienne S. Juarascio
Comparisons of meal and snack frequencies were used to assess for the presence of actual caloric restriction. Chi-square analyses revealed significant differences in frequency of meal or snack consumption between the groups (all ps < .001). Table 4 shows the frequency of meals and snacks consumed in the past 28 days for all participants. As hypothesized, compared to the OW-BN and NOW-BN groups, on average, O-BN group ate more regularly throughout the day. For example, 25% of O-BN group consumed at least three meals and two snacks in the past 28 days compared to 12.1% and 13% in OW-BN and NOW-BN groups, respectively. Both NOW-BN and OW-BN evidenced dietary restriction. For example, 31.8% and 31.3% in the OW-BN and NOW-BN group, respectively, endorsed skipping breakfast and 18.1% and 28.1% reported skipping lunch on half of the past 28 days. Dinner was the most consumed meal for all the groups in the past 28 days.
Hesperidin augments the health beneficial effects of alternate day fasting in male rats
Published in Egyptian Journal of Basic and Applied Sciences, 2023
Sukanya Bhoumik, Rashmi Kesherwani, Raushan Kumar, Syed Ibrahim Rizvi
Aging is a biological phenomenon which leads to loss of metabolic homeostasis, eventually damaging internal cellular integrity and increasing risk for major age-related pathologies [1]. One of the most robust mechanisms to attenuate aging is caloric restriction (CR), an intervention which involves restricting the amount of caloric intake without reducing nutritional efficiency and this strategy has been proposed to help in attaining longer and healthier lifespan [2]. CR has been applied successfully in many model organisms although studies in humans suggest several complications associated with nutritional intake and the observed efficacy of CR is not found to be the same as observed in other organisms. Moreover, it also has some repercussions associated with bone health, loss of libido amongst others [3]. A slightly different approach from CR is Intermittent Fasting (IF), another dietary restriction (DR) strategy based on limited feeding along with subsequent periods of total abstinence from food (fasting) and is an effective method known to reduce biomarkers of aging and promote healthspan [4]. Alternate day fasting (ADF) is one of the subtypes of IF regimens and is defined as an alternate sequence of feeding and fasting days which may be classified as periodic caloric restriction.
Effect of fasting on body composition and proteolysis gene expression in skeletal muscles and liver of BEH+/+ and BEL mice
Published in Growth Factors, 2020
Edgaras Lapinskas, Raulas Krusnauskas, Agne Cekanauskaite, Aivaras Ratkevicius
Caloric restriction and fasting are considered to be safe and effective interventions against obesity (Varady 2011; Mattson, Longo, and Harvie 2017; Wilhelmi de Toledo et al. 2019). However, fasting-induced adaptations vary between tissues and loss of lean body mass presents a major challenge for application of such interventions in people affected by ageing-related and disease-related muscle weakness (Coker and Wolfe 2018). Approximately 25% of weight loss can be accounted for by loss of lean body mass in humans subjected to intermittent fasting (Hoddy et al. 2014). The physiological mechanisms determining variations in loss of lean body mass between individuals are not well understood, but animal studies suggest that these variations could be associated with severity of caloric restriction (Mitchell et al. 2015b), metabolic rate (Hambly and Speakman 2005) and body composition as large fat reserves might help to maintain lean body mass under conditions of energy deficit (Fokin et al. 2019; Minderis et al. 2020).