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Agro-Technology of Important Medicinal Plants
Published in Namrita Lall, Medicinal Plants for Cosmetics, Health and Diseases, 2022
Nikita Patel, Swetal Patel, Abdullahi A. AbdulRahaman, Ramar Krishnamurthy
Indian industries buy Chitrak roots for their various drug formulations and herbal products. There are herbal products available in the Indian market prepared from their roots. Intercropping of Chitrak with other tree crops like Phyllanthus emblica (Amala) is recommended for commercial cultivation for obtaining a remunerative yield and economic viability (Figure 25.2F). In our earlier study, we found that application of Azospirillum and PSB to the soil improved plant height and root yield, and thereby, the crop is ready to harvest after 12 months (Patel, 2016; Patel et al., 2016). Furthermore, silver nanoparticles synthesized from the root extract of Plumbago zeylanica showed a toxic effect on Bacillus cereus, Staphylococcus aureus, Serratia marcescens and Escherichia coli, and therefore is recommended as an antimicrobial agent (Patel and Krishnamurthy, 2015).
To Evaluate the Role of a Novel Herbal Formulation by Topical Application in Cancer Therapeutics (Mouse Model)
Published in Parimelazhagan Thangaraj, Phytomedicine, 2020
Umrao Ankita, A. Rao Gururaj, S. G. A. Rao, A. Rao Jyothsna
Mice with growing Ehrlich ascites cells (in the peritoneum region) were obtained from the Amala Cancer Research Centre, Thrissur, Kerala and were grown for 10–15 days in vivo. The fur was removed in groups II–V using a hair removal cream before tumor induction. The ascites was removed, counted, and checked for the viability of cells using Trypan blue. Ninety-eight percent viable, 2 × 106 cells/200 µL were injected intramuscularly at the right hind limb region of each mouse for further experiment (Figure 19.1).
Larval and gut enzyme toxicity of n-hexane extract Epaltes pygmaea DC. against the arthropod vectors and its non-toxicity against aquatic predator
Published in Toxin Reviews, 2021
Kesavan Amala, Raja Ganesan, Sengodan Karthi, Sengottayan Senthil-Nathan, Muthiah Chellappandian, Patcharin Krutmunag, Narayanaswamy Radhakrishnan, Faruq Mohammad, Athirstam Ponsankar, Prabhakaran Vasantha-Srinivasan
Relative to the above research, the Epaltes genus is utilized in the traditional medicine in South Asian countries with wide therapeutic actions. The species Epaltes pygmaea DC. and Epaltes divaricata (L.) Cass. were widely spread in Southern India that belong to Asteraceae family that grows up to 20cm with branched stem and fragrant roots grounded in the river banks across the paddy field post-harvesting (Amala and Amerjothy 2016, Mrugammal et al.2018). The selected plant material is widely distributed and cost effective as compared to other chemical pesticides. Overall, the present research will be a novel attempt on improving natural larvicidal agents against dengue and malarial virus mosquito vector with harmless responses against the non-target aquatic predators. In this context, the present research was aimed to investigate the bio-efficacy of crude n-hexane extracts E. pygmaea (NH-Epx) on larval toxicity, enzyme inhibition, repellent, and non-target toxicity against the dengue, filariasis vector, and beneficial aquatic predator Toxorhynchites splendens, respectively.
Low number of KIR ligands in lymphoma patients favors a good rituximab-dependent NK cell response
Published in OncoImmunology, 2021
Dhon Roméo Makanga, Maxime Jullien, Gaëlle David, Nolwenn Legrand, Catherine Willem, Léa Dubreuil, Alexandre Walencik, Cyrille Touzeau, Thomas Gastinne, Benoit Tessoulin, Steven Le Gouill, Béatrice Mahé, Katia Gagne, Patrice Chevallier, Béatrice Clemenceau, Christelle Retière
PBMCs were isolated as previously described.11 All blood donors were recruited at the Blood Transfusion Center (EFS, Nantes, France) and informed consent was given by all individuals. The following CD20+ HLA class I homozygous EBV-transformed B lymphoblastoid cell lines were used as targets for functional assays: AMALA (HLA-B*15:01, -C*03:03, and Bw4−/C1C1), SP001 (HLA-B*44:02, -C*05:01, and Bw4+/C2C2) and RSH (HLA-B*42:01, -C*17:01, and Bw4−/C2C2). Cell lines were cultured in RPMI 1640 medium (Gibco, Paisley, Scotland, UK) containing glutamine (Gibco) and penicillin-streptomycin (Gibco) and supplemented with 10% fetal bovine serum (Gibco). Mycoplasma tests performed by PCR were negative for all cell lines.
Antidiabetic Activity of Triticum aestivum Seed–Based Diet on Alloxan-Induced Diabetic Rats
Published in Journal of Dietary Supplements, 2020
B. O. Ajiboye, H. O. B. Oloyede, M. O. Salawu
Triticum aestivum seed belongs to the family Poaceae; it has been characterized with high levels of soluble dietary fiber, protein, monounsaturated fatty acids, and antioxidants, among others (Ajiboye et al. 2015; Mohan et al. 2013). Dioscorea rotundata (white yam) is one of the commonest yam flour in Nigeria for preparing “Amala.” Almost all families living in the western part of Nigeria consume this in the diet at least once daily.