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Anti-Hyperglycemic Property Of Medicinal Plants
Published in Amit Baran Sharangi, K. V. Peter, Medicinal Plants, 2023
Karanpreet Singh Bhatia, Arpita Roy, Navneeta Bhardavaj
Abelmoschus esculentus commonly known as okra, belongs to family Malvaceae, is primarily from Ethiopia but now can be found in region such as West Africa, Caribbean, Asia, and United States. Ben-Chioma et al. (2013) reported that dried powdered and aqueous form of A. esculentus has remarkably showed an antihyperglycemic effect and lowered the blood glucose concentration in alloxan induced (AI) hyperglycemic Wister rats. Anti diabetic property of okra is found to be linked with dietary fibers and polyphenols (Gunness et al., 2010). In another study, okra extract has improved histological damages in pancreatic beta cells and have shown to reduce the expression levels of PPAR-α and γ gene which results in decrease in incidence of type 2 diabetes (Erfani et al., 2018).
Impact of Industrial Wastewater on Medicinal Plant Growth
Published in Azamal Husen, Environmental Pollution and Medicinal Plants, 2022
Okra (Abelmoschus esculentus) is a vegetable that belongs to the family Malvaceae, cultivated as a garden crop or on a commercial scale in several countries, such as India, Iran, Pakistan, Bangladesh, Japan, Thailand, Afghanistan, Turkey, Ethiopia, and Western Africa. Okra is not a staple food, consumed as diet food and its seeds are rich in protein (lysine, tryptophan), unsaturated fatty acid (linoleic acid), and phenolic compounds. Okra contains folate, ascorbic acid, vitamin B, fibre, calcium, iron, zinc, manganese, and potassium (Moyin-Jesu 2007; Gosslau and Chen 2004). The medicinal benefits of okra include prevention or treatment of chronic diseases such as cancer, heart disease (hypocholesterolemic effect), regulating the absorption of blood sugar, gastro-protective, anti-ulcerogenic, and diuretic, chemo-preventive agents, and many more (Kendall and Jenkins 2004; Gemede et al. 2015). The effect of various soap and detergent effluent concentrations (1%, 05%, 10%, 20%, 25%, 50, 75%, and 100%) conducted on the medicinal plant okra in Nigeria reveals that wastewater below 50% only supports germination, flowering after 37 days (treated with 1%, 5%, 10% concentration), and greener colour (with 1%, 5%, 10% concentration). Thus, for irrigation purposes, detergent and soap effluent below 5% can be used, due to lower concentrations of nitrogen and phosphate (Fatoba et al. 2011).
Neuroprotective Role of Quercetin in Alzheimer’s Disease
Published in Atanu Bhattacharjee, Akula Ramakrishna, Magisetty Obulesu, Phytomedicine and Alzheimer’s Disease, 2020
Abelmoschus esculentus (AE), commonly known as okra, is a vegetable which is well known for its antidiabetic effect (Chiu and Chang, 1995; Council, 2006; Huang et al., 2019). AE extracts F1 (with high concentrations of quercetin glucosides and the triterpene ester) and F2 (with a high concentration of polysaccharides) substantially inhibited dipeptidyl peptidase-4 (DPP-4)-mediated apoptosis (Huang et al., 2019). F1 inhibited Aβ-instigated caspase-3 expression at a concentration of 25 µg/mL, whereas F2 inhibited caspase-3 activation at 1 µg/mL (Huang et al., 2019). Both fractions reduced Aβ-increased DPP-4 activity but increased Aβ-reduced phospho-AMPK (p-AMPK) concentration and phosphorylation of phosphatidylinositol 3-kinase (p-PI3K) (Peng et al., 2016; Huang et al., 2017, 2019).
In vivo anti-ulcerogenic effect of okra (Abelmoschus esculentus) on ethanol-induced acute gastric mucosal lesions
Published in Pharmaceutical Biology, 2018
Deniz Ortaç, Mustafa Cemek, Turan Karaca, Mehmet E. Büyükokuroğlu, Zafer Ö. Özdemir, Ayşe Tuba Kocaman, Sadık Göneş
The toxicity symptom of the okra was not recorded in mice. Also, LD50 value was not observed up to 5000 mg/kg of the okra extract in the present study. The mice did not show any abnormal signs and diarrhea in the acute toxicity study. Okra is a therapeutic vegetable that could be safely consumed.