China
Africa
Explore chapters and articles related to this topic
Insect Venom Allergy
Published in Pudupakkam K Vedanthan, Harold S Nelson, Shripad N Agashe, PA Mahesh, Rohit Katial, Textbook of Allergy for the Clinician, 2021
William H Bermingham, Alex G Richter, Mamidipudi T Krishna
Cardiovascular comorbidities: This has been connected with poor outcomes in all-cause anaphylaxis in numerous studies (Stoevesandt et al. 2019). Data are sparse for the specific context of venom allergy and results are variable. Kounis syndrome (cardiac ischaemia or infarction in the context of anaphylaxis) has been reported in case studies of venom allergy.
Piperacillin–Tazobactam
Published in M. Lindsay Grayson, Sara E. Cosgrove, Suzanne M. Crowe, M. Lindsay Grayson, William Hope, James S. McCarthy, John Mills, Johan W. Mouton, David L. Paterson, Kucers’ The Use of Antibiotics, 2017
Piperacillin may provoke any of the reactions that occur with penicillin G; thus piperacillin is contraindicated in patients with a history of penicillin hypersensitivity. In a survey of 485 hospitalized patients treated by piperacillin, the frequency of hypersensitivity reactions, such as drug fever, rashes, pruritus, and eosinophilia, was approximately 4% (Gooding et al., 1982). Among 63 patients whose chronic Pseudomonas osteomyelitis was treated with high doses of extended spectrum penicillins for prolonged periods, side effects such as rash, drug fever, and eosinophilia were more common in patients treated with ureido-penicillins than those treated with carbenicillin (Fahim et al., 2006; Lang et al., 1991). Rarely, severe skin reactions such as acute exanthematous pustulosis and anaphylaxis-mediated coronary vasospasm (Kounis syndrome) can occur (Calogiuri et al., 2012; Huilaja et al., 2014).
Kounis syndrome following COVID-19 vaccination
Published in Baylor University Medical Center Proceedings, 2022
Chadi Allam, Nicholas G. Kounis, Roy Chlawit, Marc Saouma, Georges Badaoui
The difficulty in this unique clinical case is to determine whether the vaccine dose caused the coronary event.1 Type III Kounis syndrome is a highly possible diagnosis. Kounis syndrome is an acute coronary syndrome triggered by an allergic reaction. It is underdiagnosed, and its pathophysiology is still not fully elucidated. Different mechanisms can lead to an acute coronary syndrome during an allergic reaction, leading to a classification with four types.2 Coronary spasm in normal coronary arteries characterizes type I, atheromatous plaque rupture or coronary spasm with a preexisting atheromatous disease defines type II, and stent thrombosis defines type III. Recently, Giovannini et al added type IV to the classification, which involves a coronary artery bypass graft thrombosis.2
Acute coronary syndrome from scombroid poisoning: a narrative review of case reports
Published in Clinical Toxicology, 2022
Cesare de Gregorio, Giuseppe Ferrazzo, Ioanna Koniari, Nicholas G. Kounis
Kounis syndrome is an anaphylactic illness related to IgE-antigen immune complexes that activate mast-cells, basophils, macrophages, and cytokine system after the ingestion of an allergen [23,31]. Cases of KS have occurred after honeybee and Hymenoptera stings, ingestion of drugs, fish-foods, blue-crabs, and after the exposure to chemical or contrast agents during coronary angiography [23,44–47,52]. There are three variants of KS. Type I is an ACS characterized by coronary vasospasm, not necessarily resulting in myocardial infarction, in patients with normal or nearly normal coronary arteries. Type II involves ACS patients with pre-existing CAD, often complicated by coronary vasospasm, plaque disruption and thrombosis, resulting in myocardial infarction. Type III consists of thrombotic/stenotic inflammation of pre-existing coronary artery stents. Most cases of scombroid in this series were like Type I, with the sole exception of a non-allergic causality. Unless antihistamines promptly resolve cardiac symptoms and any ECG changes, coronary angiography is mandatory in KS patients [17,18,23,25].
Allergic myocardial infarction: Type I Kounis syndrome following blue crab consumption
Published in Acta Clinica Belgica, 2019
Volkan Dogan, Oğuzhan Çelik, Bülent Özlek, Eda Özlek, Cem Çil, Özcan Başaran, Murat Biteker
Although myocardial infarction due to an allergic insult is first described in 1950 [1], the first definition of allergic angina and allergic myocardial infarction as a different clinical entity is made 41 years after the first report [2]. Kounis syndrome is caused by inflammatory mediators such as histamine, neutral proteases, arachidonic acid products, and a variety of cytokines and chemokines released, during mast cell degranulation [2]. There are several factors and diseases which may induce Kounis syndrome such as hymenoptera (e.g. bee) and viper venom, food allergens (e.g. shellfish), oral and parenteral drugs, stings by ants and jellyfishes, various conditions (angioedema, bronchial asthma, urticaria, exercise-induced allergy, mastocytosis, and serum sickness), and a variety of environmental exposures (e.g. grass cutting, poison ivy, latex contact, limpet ingestion, and millet allergy) [3]. Two specific diseases that are associated with Kounis syndrome, Anisakiasis and Scombroid syndromes together with fish skin contact, fish skin prick, fish inhalation, and fish-made gelatins constitute the whole causative spectrum of fish-induced allergic or allergy-like manifestations [4]. Herein, we report the first case of Kounis syndrome after consumption of blue crab.