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Synovial Sarcoma
Published in Dongyou Liu, Tumors and Cancers, 2017
Tumors of uncertain differentiation may be differentiated into (1) benign (intramuscular myxoma [including cellular variant], juxta-articular myxoma, deep [“aggressive”] angiomyxoma, pleomorphic hyalinizing angiectatic tumor, and ectopic hamartomatous thymoma), (2) intermediate (rarely metastasizing) (angiomatoid fibrous histiocytoma, ossifying fibromyxoid tumor [including atypical and malignant], and mixed tumor [myoepithelioma and parachordoma]), and (3) malignant (synovial sarcoma, epithelioid sarcoma, alveolar soft part sarcoma, clear cell sarcoma of soft tissue, extraskeletal myxoid chondrosarcoma [“chordoid” type], primitive neuroectodermal tumor [PNET]/extraskeletal Ewing tumor, desmoplastic small round cell tumor, extra-renal rhabdoid tumor, malignant mesenchymoma, neoplasms with perivascular epithelioid cell differentiation [PEComa], clear cell myomelanocytic tumor, and intimal sarcoma) [1].
Which women develop vulvar cancer?
Published in Miranda A. Farage, Howard I. Maibach, The Vulva, 2017
Malignant tumors of the vulva account for approximately 5% of the malignancies found in the female genital tract. Squamous cell carcinoma accounts for 90%–95% of these tumors; the others are basal cell carcinoma, melanoma, adenocarcinoma, and mesenchymal tumors (e.g., aggressive angiomyxoma). Carcinoma from elsewhere in the genital tract and sometimes from the urinary or intestinal tract can metastasize to the vulva (1–3).
Incidentally detected perineal aggressive angiomyxoma in an asymptomatic patient with uterine leiomyomas
Published in Journal of Obstetrics and Gynaecology, 2021
Emre Altinmakas, Hakan Dogan, Muzaffer Temur, Serkan Guneyli
Aggressive angiomyxoma is a rare mesenchymal neoplasm that is predominantly seen in pelvic region of women (van Roggen et al. 2005). Deep pelvic soft tissues and perineum in women and periscrotal region in men are the most common locations (Amezcua et al. 2005). The tumour is called ‘aggressive’ due to deep soft tissue infiltration that causes local recurrence after surgical resection. We report a patient with aggressive angiomyxoma in the pelvic-perineal region that was incidentally detected on magnetic resonance imaging (MRI) which was performed for surgical planning of uterine fibroids.
Aggressive angiomyxoma of the female urethra
Published in Baylor University Medical Center Proceedings, 2022
Mohamed Elsaqa, Mahmoud Elsabbagh, Hend A. Sharafeldin, Nahed M. Baddour
Aggressive angiomyxoma (AAM) is a rare locally aggressive neoplasm of mesenchymal origin that arises predominantly in the pelvic, perineal, and vulvar regions of adult women, especially those of reproductive age. Radical excision of the AAM masses is the usual management.1,2 We report a very rare case of female urethral AAM with an unusual presentation.