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Chronic Rhinosinusitis
Published in Raymond W Clarke, Diseases of the Ear, Nose & Throat in Children, 2023
There is good evidence to support adenoidectomy for recalcitrant CRS, perhaps because the adenoids act as a reservoir of continuous infection. Maxillary antral lavage has been widely used in the past and is often combined with adenoidectomy. The exact role of functional endoscopic sinus surgery (FESS) is not fully established, but it is frequently used with some evidence of symptomatic improvement. Middle meatal antrostomy and limited removal of diseased mucosa rather than extensive exenteration of the paranasal sinuses is probably all that is needed. Turbinate reduction surgery is often offered as a last resort to improve severe nasal obstruction, but the effect, if any, tends to be short-lived.
Nasal Airway Surgery: Management of Enlarged Turbinates
Published in R James A England, Eamon Shamil, Rajeev Mathew, Manohar Bance, Pavol Surda, Jemy Jose, Omar Hilmi, Adam J Donne, Scott-Brown's Essential Otorhinolaryngology, 2022
Compensatory enlargement of the inferior turbinate is often observed on the opposite side to a septal deflection. Histological studies of the inferior turbinate have shown that the enlargement of the turbinate on the contralateral side to the septal deviation may be due to an increase in the conchal bone as well as increased mucosal thickness. Recent findings favour turbinoplasty in patients with clinically confirmed unilateral inferior turbinate hypertrophy.
Rhinolaryngoscopy for the Allergist
Published in Pudupakkam K Vedanthan, Harold S Nelson, Shripad N Agashe, PA Mahesh, Rohit Katial, Textbook of Allergy for the Clinician, 2021
Jerald W Koepke, William K Dolen
The superior turbinate is a short, oblique structure located superior and posterior to the middle turbinate. The posterior ethmoid sinuses drain into the superior meatus (Fig. 11.5). A supreme turbinate medial to the superior turbinate is occasionally noted.
Evaluation of nasal function after endoscopic endonasal surgery for pituitary adenoma: a computational fluid dynamics study
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2022
Miao Lou, Luyao Zhang, Simin Wang, Ruiping Ma, Minjie Gong, Zhenzhen Hu, Jingbin Zhang, Yidan Shang, Zhenbo Tong, Guoxi Zheng, Ya Zhang
In a similar manner to airflow distribution, changes in temperature and humidity in the C7 section also mainly occurred in the MTR region. The decreasing trend in temperature and humidity in the C7L plane was consistent with that in the LM, while the changes of other parts were small. Therefore, the decrease in warming and humidification in the nasal cavity is mainly affected by MTR. The risks and benefits of MTR have been debated in the literature for many years. Those that prefer excision believe that it contributes to improved intraoperative visualization, increased convenience of postoperative examination, and improved long-term patency (Stewart 1998; Havas and Lowinger 2000). Conversely, those who favor preservation argue that MTR masks intraoperative markers and increases the risk of frontal sinusitis, nasal scabs, and ENS (LaMear et al. 1992; Zhao et al. 2004; Nurse and Duncavage 2009). In the present study, it was found that MTR affects airflow and nasal heating and humidification, which could explain postoperative nasal scabs and other symptoms. We recommend minimizing damage to the middle turbinate even if considered necessary by the premise of the view of the surgical site.
Identifying chronic rhinosinusitis without nasal polyps by analyzing aspirated nasal air with an electronic nose based on differential mobility spectrometry
Published in Acta Oto-Laryngologica, 2022
Jussi Virtanen, Anton Kontunen, Jura Numminen, Niku Oksala, Markus Rautiainen, Antti Roine, Ilkka Kivekäs
The potential use of a breathomics-based approach in addition to the instruments currently used to identify CRS is intriguing. However, it cannot replace clinical examination, such as observing intranasal findings. As phenotyping asthma from exhaled breath is already possible [5], the same could perhaps be done for CRS phenotyping by analyzing nasal air. At present, however, eNose technology is not ready for use in the diagnostics of CRS. Therefore, to evaluate the ability of DMS or other eNoses to diagnose CRS further, a larger study containing a control group of patients who have symptoms positive for CRS, according to established criteria, but negative CT findings should be undertaken. This would lead to a diverse etiology of symptoms, such as allergic and non-allergic rhinitis, DS, and hypertrophy of the inferior turbinates. These etiologies could have an impact on the nasal air profile and would require a larger number of samples to build a trustworthy classifier. Furthermore, patients with different endotypes and phenotypes of CRS should be evaluated as their VOC profile could differ from each other. Preliminary findings show that CRSsNP was distinguished from CRS patients with polyps with an accuracy of 67% [8]. In addition, the impact of disease severity based on symptoms and objective findings to the VOC profile should be further evaluated.
The impact of allergies and smoking status on nasal mucosa of hypertrophied turbinates – an immunohistologic analysis
Published in Inhalation Toxicology, 2020
Meir Warman, Evelyn Tiomkin, Monica Huszar, Doron Halperin, Ilan Asher, Oded Cohen
The study cohort consisted of fifty-three patients, male and female, with inferior turbinate hypertrophy that underwent turbinate reduction at Kaplan Medical Center between 2014 and 2016. All patients were evaluated preoperatively in our department’s outpatient clinic. The patients were asked regarding the duration of nasal blockage symptoms, existence of comorbidities and prior medical treatments, such as intranasal steroids. All patients underwent a complete examination including anterior rhinoscopy and fiberoptic examinations of both sides to exclude the presence of nasal polyps or a neoplastic etiology mandating additional surgery. Patients were eligible for surgery if the attending physician was impressed by the severity of complaints, correlation of symptoms with physical examination findings (i.e. hypertrophied turbinates blocking the nasal air passage), and failure of alternative medical treatment. Turbinate reduction was carried out under general anesthesia in an operating room, using cold instruments, to allow for a specimen biopsy. Biopsies were sent in formalin solution for permanent fixation in the pathology lab.