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Tumours of the oral cavity and pharynx
Published in Anju Sahdev, Sarah J. Vinnicombe, Husband & Reznek's Imaging in Oncology, 2020
Kunwar S S Bhatia, Ann D King, Robert Hermans
The floor of the mouth is located beneath the mobile tongue and is enclosed by the lower alveolar ridges. Its inferior boundary includes the sheet-like mylohyoid muscle, separating the floor of the mouth from the submental space below. Its contents are within the sublingual spaces, which include the sublingual and minor salivary glands, the submandibular duct (Wharton duct), and a part of the hyoglossus muscle, as well as the lingual artery, vein, and lingual and hypoglossal nerves. The vessels and nerves are often termed the lingual neurovascular bundle.
Anatomy and Embryology of the Mouth and Dentition
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Because of the potential of inflammation associated with the tissues surrounding partially erupted, impacted third molars (pericoronitis), the spaces associated with this region are particularly important and, as they are interconnected, inflammation can spread to involve the tissue spaces of the neck. The submental and submandibular tissue spaces are located below the inferior border of the mandible, beneath the mylohyoid muscle, in the suprahyoid region of the neck. The submental space lies beneath the chin in the midline, between the mylohyoid muscles and the investing layer of deep cervical fascia. It is bounded laterally by the two anterior bellies of the digastric muscles. The submental space communicates posteriorly with the two submandibular spaces. The submandibular space is situated between the anterior and posterior bellies of the digastric muscle. It communicates with the sublingual space around the posterior free border of the mylohyoid muscle.
Vaccination with a nanoparticle E7 vaccine can prevent tumor recurrence following surgery in a human papillomavirus head and neck cancer model
Published in OncoImmunology, 2021
Sonia Domingos-Pereira, Vincent Roh, Agnès Hiou-Feige, Gabriele Galliverti, Christian Simon, Genrich V. Tolstonog, Denise Nardelli-Haefliger
For orthotopic tumors, 100ʹ000 mEERL95 cells were injected into the cervical subcutaneous tissue (the submental space) as previously described.7,12,13 For flank tumors, 100ʹ000 mEERL95 and 100ʹ000 TC-1 cells were subcutaneously implanted on each flank of the mice. Tumor growth was monitored with a Vernier caliper, and tumor volume was calculated as V = (L x W2)/2. Procedure for surgery at the neck region were previously detailed.7,14 Briefly, with the help of a stereomicroscope, tumors were dissected and wounds were closed with a suture. At the time of surgery, tumor invasion of the bone and muscle were recorded.
Letter to the Editor
Published in Developmental Neurorehabilitation, 2019
All studies have in common that they have used the tape for a short period of time. A further suggestion might be to apply the tape for a longer period of time. The S-tape is a tape applied to the submental space to address drooling [7]. Clinical experience with this tape over eight years has taught us that, in the cases of patients with a central nervous system disorder or genetic disorder, the tape application will be effective only as long as it is applied. There is little to no carry-over effect reported so far.