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Nanopharmaceuticals in Alveolar Bone and Periodontal Regeneration
Published in Harishkumar Madhyastha, Durgesh Nandini Chauhan, Nanopharmaceuticals in Regenerative Medicine, 2022
Mark A. Reynolds, Zeqing Zhao, Michael D. Weir, Tao Ma, Jin Liu, Hockin H. K. Xu, Abraham Schneider
The root surfaces of healthy human teeth following extraction provide a significant source of hPDLSCs. The PDL tissues contain various cell types including fibroblasts, cementoblasts, osteoblasts, endothelial cells, and epithelial cells (Lekic et al. 2010). Regeneration of the periodontal attachment apparatus, including new bone, cementum, and periodontal ligament, involves highly coordinated osteogenesis, cementogenesis, and fibrogenesis because a new fibrous attachment is dependent on formation of new bone and cementum (Zeichner-David 2006).
Mesenchymal Stem Cells from Dental Tissues
Published in Vincenzo Guarino, Marco Antonio Alvarez-Pérez, Current Advances in Oral and Craniofacial Tissue Engineering, 2020
Febe Carolina Vázquez Vázquez, Jael Adrián Vergara-Lope Núñez, Juan José Montesinos, Patricia González-Alva
In the last few decades, several studies have reported that human tooth germs contain multipotent cells that give rise to dental and periodontal tissues (Yalvac et al. 2010). The dental pulp, particularly from third molars, have shown to be a significant stem cell source (Arthur et al. 2009).
Nutraceuticals for Maternal and Offspring’s Dental Health
Published in Priyanka Bhatt, Maryam Sadat Miraghajani, Sarvadaman Pathak, Yashwant Pathak, Nutraceuticals for Prenatal, Maternal and Offspring’s Nutritional Health, 2019
Amanda Rodrigues, Amorim Adegboye
Human tooth development is unique, as it is formed during a limited period of time and remains relatively stable in its structure and metabolism after mineralization (Jontell & Linde 1986). For human teeth to be healthy, all parts of the tooth must develop appropriately during key stages of fetal life. Thus, the intrauterine milieu, influenced by maternal nutrition, smoking habits, and alcohol consumption, can affect the formation, development, and mineralization of a child’s teeth (Jontell & Linde 1986). Some nutrients have been linked to the development of enamel defects (lack of vitamin D), periodontal disease (lack of vitamin C), and caries (free sugars, lack of fluoride), but, generally, only a few experimental studies have examined the effect of nutraceuticals on the prevention, delay of disease onset, and progression and treatment of dental diseases (Varela-López et al. 2018).
Interaction between microorganisms and dental material surfaces: general concepts and research progress
Published in Journal of Oral Microbiology, 2023
Yan Tu, Huaying Ren, Yiwen He, Jiaqi Ying, Yadong Chen
Superhydrophilic surfaces can form water molecule surfaces with good antifouling performance. Since the strong interaction force between the surface and water makes the contact angle equal to or close to 0, this property weakens the interaction of matrix material, reducing cell adhesion. The features of Zwitterion-based mixed matrix membranes include enhanced water flux, fouling mitigation, and selectivity. They have emerged for oilsands process-affected wastewater as an improved membrane treatment. Zwitterionic structures with the advantage of superhydrophilicity have attracted significant attention in this field [42]. MPC (2-methacryloyloxyethyl phosphorylcholine) is well-known as a zwitterionic polymer/monomer exhibiting superhydrophilic properties [43]. However, the application of superhydrophilic surfaces in the oral cavity should still be studied. Interestingly, Venault et al. [44] reported that coating the surface with zwitterionic polymer SBMA could inhibit the adhesion of lysozyme because zwitterionic molecules could capture water to become superhydrophilic. Some relevant tests result reflected that 70% of oral bacteria adhering to human teeth were inhibited [44]. With the continuous advances in material science and manufacturing technology, there will be more interesting developments in this area in the future.
Retrospective physical dosimetry in the Czech Republic: an overview of already established methods and recent research
Published in International Journal of Radiation Biology, 2022
Daniela Ekendahl, Zina Čemusová, Dan Reimitz, Jakub Vávra
The human teeth were obtained from donors. They were extracted for medical reasons. The quality of the teeth was rather poor. Most of the teeth were worn and the dental enamel was partially abraded. In some cases, traces of dirt or tartar were evident. Some of the teeth were repaired with a dental ceramic or dental cement. All the teeth used were carefully disinfected and cleaned. Tooth crowns were separated from the roots and obvious residual organic parts. The teeth without a dental repair material were crushed using a mortar and a pestle. The material contained both tooth enamel and dentin. It was difficult to separate only the enamel. The powder was sieved into grain sizes less than 100 µm. Portions of 5 mg of the powder were used as aliquots for the measurements. The reason for using the material in form of powder was to increase its radiation sensitivity (DeWitt et al. 2010). Fragments of the teeth with some dental repair were used in their intact form.
Ultrasonic measurement of dentin remineralization effects of dentifrices and silver diamine fluoride
Published in Acta Odontologica Scandinavica, 2021
Kengo Wakamatsu, Hiroyasu Kurokawa, Taketo Okuwaki, Toshiki Takamizawa, Akimasa Tsujimoto, Koji Shiratsuchi, Ryo Ishii, Masashi Miyazaki
Human teeth are exposed to many physical, chemical and mechanical challenges during everyday life that cause varying levels of tooth decay. Root caries have increased in prevalence as people live longer and retain their natural teeth to old age [1]. Root caries formation is determined by the presence of a cariogenic biofilm and fermentable carbohydrates and is exacerbated by the complex dynamic of dentin tissue [2]. Apatite crystals in dentin have a higher carbonate content than enamel, and their demineralization process involves collagen breakdown, which makes their components more water soluble and susceptible to acidic dissolution than those in enamel [3]. Although root caries can be observed in young adults, exposure of the root surface due to periodontal disease leads to an increased prevalence of root caries in older adults [4]. Root surfaces are more susceptible to bacterial accumulation when cleaning is inadequate due to their roughness and retentive anatomy, leading an increased risk for the development and progression of root caries [5].