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Metering Pumps
Published in Béla G. Lipták, Flow Measurement, 2020
The peristaltic pump has found particularly large acceptance in the medical and biochemical fields where high accuracy, low flow rates, inherent enclosure of the fluid, and sterilization are prime requirements. The flow rate of the peristaltic pump can be adjusted by changing the speed of the squeezing mechanism. Power to these pumps is usually provided by 60-Hz, 110-volt electrical motors. Air-operated and electrical explrjsion-proof motors are also available.
Fluid Flow
Published in C. Anandharamakrishnan, S. Padma Ishwarya, Essentials and Applications of Food Engineering, 2019
C. Anandharamakrishnan, S. Padma Ishwarya
In a peristaltic pump (Figure 4.24), a lengthy flexible tube is squeezed by a series of moving rollers, which cause the trapped liquid to move along with the tube. Here, the discharge rate is constant and these pumps are mostly suited for small flow rate applications without leakage and air exposure. Peristaltic pumps are more hygienic in operation compared to the other pumps and thus find wide applications in the biotechnology and pharmaceutical industries.
High Speed, Automated Filling of Sterile Liquids and Powders
Published in Kenneth E. Avis, Sterile Pharmaceutical Products, 2018
Peristaltic. The peristaltic pump is a motor-driven mechanical roller applying pressure on flexible tubing. As the roller impinges the tubing, fluid is trapped inside the tubing and moved through the tubing as the roller advances. A rotational configuration is the most common. There are other linear displacement pumps where the tubing is in a flat plane and rollers move along that plane. In either case a certain fixed volume of liquid is moved with each stroke or impingement. The most significant advantage of this method is the lack of any mechanical parts in the liquid path. Since the liquid path is sealed and isolated, products requiring total containment can be pumped in this manner. The system can be run dry without damaging components. The absence of seals or mechanical parts yields a relatively clean system. Changeover is simplified in that the tubing can be replaced without part cleaning and sterilization. Tubing replacement is relatively easy.
Experimental investigation on effect of accelerated speed and rotor material on life of implantable micro-infusion pump tubing
Published in Journal of Medical Engineering & Technology, 2022
Sarath S. Nair, Adhin D, Sudheesh K S
Peristaltic positive displacement pumps are widely used in clinical applications, as the fluid being pumped comes in contact only with the inner surface of the tubing. Thus, only the composition of the tubing is needed to be checked for compatibility. This makes the peristaltic pump an excellent candidate for biomedical applications like the transfer of body fluids and medication [1]. However, most of these pumps are kept external and the issues of mechanical rigidity and wear and tear of the tubes are of little concern. Recent literature suggests the usage of these pumps as implantable drug delivery devices [2–4] for controlled drug release to targeted locations of the body, especially for insulin management and cancer therapy. These pumps are required to be working within the body for a long time.
Model-based design of tube pumps with ultra-low flow rate pulsation
Published in SICE Journal of Control, Measurement, and System Integration, 2022
Jinhui Yang, Kentaro Hirata, Yukinori Nakamura, Kunihisa Okano, Kenichi Katoh
A tube pump, sometimes called a peristaltic pump, is a fluid transfer mechanism that transports the fluid inside an elastic tube by squeezing the tube from the outside (Figure 1). For a concise review of this pump from an engineering viewpoint, the readers are referred to [1]. The largest advantage of the tube pump is that it causes no contamination of the fluid inside from its structure. This is promising for biological, medical, health-care or other application fields, e.g. [2–6]. Typically, tube pumps are driven with a constant rotation speed reference. Due to the periodic nature of the pump operation, its tracking problem is studied under the context of repetitive control, e.g. [7–9]. Further, even when the effect of the periodic disturbance on the rotation speed is completely removed, a plain implementation inevitably introduces a pulsation of the flow rate also from its structure. To remedy this, different types of tube pump or control strategies are investigated in the patents, e.g. [10, 11] and the literature, e.g. [12–15]. From their personal experiences in developing the pumps in [14, 15], the authors are strongly motivated to have a systematic understanding on the design issue, rather than isolated knowledge on particular cases. For this purpose, we study how pulsation is generated and review what we can do to prevent it based on mathematical models in this paper. Our model-based design concept is integrated step by step toward the final proposal.