Latex agglutination

Latex agglutination is a diagnostic technique that involves the aggregation of latex particles in response to antibody and antigen interactions. This technique is easy to apply, low-cost, non-hazardous, nontoxic, and able to quickly provide results. The latex agglutination test is a simple, rapid, and cost-effective test that is particularly useful in developing countries.From: Production and characterization of a conserved M2e peptide-based specific IgY antibody: evaluation of the diagnostic potential via conjugation with latex nanoparticles [2018], Environmental Technology and Engineering Techniques [2020]

Infectious Bursal Disease

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Published in Moayad N. Khalaf, Michael Olegovich Smirnov, Porteen Kannan, A. K. Haghi, Environmental Technology and Engineering Techniques, 2020

P. Raja

The latex agglutination test is a simple, rapid and cost-effective test and thus quite applicable in developing countries. The test can be performed in 30 min and spot detection can be done with naked eye. Nakamura et al. (1994) performed a competitive agglutination test using the polystyrene latex bound monoclonal antibody to detect the serum antibody titer against IBDV.

Production and characterization of a conserved M2e peptide-based specific IgY antibody: evaluation of the diagnostic potential via conjugation with latex nanoparticles

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Published in Preparative Biochemistry and Biotechnology, 2018

Yasemin Budama-Kilinc, Rabia Cakir-Koc, Burak Ozdemir, Zeynep Kaya, Selim Badur

Latex agglutination assays are easy to apply, low-cost, non-hazardous, nontoxic, able to quickly provide results, and based on the aggregation of latex particles in response to antibody and antigen interactions. Monoclonal antibodies are generally used in latex agglutination assays to diagnose bacteria and viruses and their induced diseases.[61] For example, a latex agglutination assay was used to diagnose several bacteria and viruses such as Leptospira,[62]Burkholderia pseudomallei,[63]Burkholderia mallei,[64]Streptococcus agalactiae,[65]Clostridium difficile,[66]Toxoplasma gondii,[67] rabies virus,[49] swine influenza virus,[68] rotavirus,[69] foot and mouth disease virus,[70] and enterovirus.[71] The current study aims to use anti-M2e IgY antibodies in a latex agglutination test to diagnose the influenza virus considering the advantages of IgY antibodies and M2e peptide.

Latex agglutination

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Infectious Bursal Disease

Production and characterization of a conserved M2e peptide-based specific IgY antibody: evaluation of the diagnostic potential via conjugation with latex nanoparticles