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History of the Frank Reidy Research Center for Bioelectrics
Published in Marko S. Markov, James T. Ryaby, Erik I. Waldorff, Pulsed Electromagnetic Fields for Clinical Applications, 2020
Several new positions were added to the FRRCBE. In 2012, Dr. Michael Kong took the Battened Endowed Chair of Bioelectrics that was previously filled by Dr. Schoenbach. Kong’s wife, Dr. Hai-Lan Chen, also joined the FRRCBE as a research associate professor. She too investigates cold plasmas for possible medical applications. Michael is perhaps the world’s leading scientist in biomedical application of cold atmospheric plasmas. This added a new application of pulsed power to the Center in the emerging field of plasma medicine. Applications include decontamination of surgical instruments, disinfecting skin and living tissues, stimulating healing of chronic wounds, and suppression of tumor growth. For example, Michael’s group demonstrated that cold plasma induces apoptosis in multiple myeloma and may provide an effective therapy (Xu et al., 2018). Cold plasma also increased the sensitivity of multiple myeloma to bortezomib and may be used in combination with plasma treatment to enhance current chemotherapy (Xu et al., 2016a). His group has shown that cold plasma might provide an efficient technique for the delivery of siRNA and miRNA in 2D and 3D culture models (Xu et al., 2016b).
Plasma Nanotechnology for Nanophase Magnetic Material Synthesis
Published in Sam Zhang, Dongliang Zhao, Advances in Magnetic Materials, 2017
Rajdeep Singh Rawat, Ying Wang
Industrial plasma applications can be broadly classified into two major areas. First is plasma processing, which typically involves the use of ions and reactive species in plasmas to modify the chemical and physical properties of a material surface. Plasma processing includes plasma activation, plasma etching, ion implantation, or surface modification through plasma functionalization, cleaning, and hardening. The second major area is plasma synthesis, which refers to the use of plasmas to drive or assist chemical reactions either to synthesize complex multicomponent compounds, alloys, or polymers starting from simpler starting precursors or to synthesize simpler material systems through the inverse processes of plasma decomposition of complex multicomponent materials. Plasma processing and synthesis of materials impact several large-scale manufacturing industries in the world, and foremost among them is the electronics industry. The several trillion dollar electronics industry uses plasma-based synthesis techniques for manufacturing very large-scale integrated (VLSI) microelectronic circuits (or chips) [3] and plasma processing for adhesion promotion of encapsulants, adhesives, and sealants by promoting their surface wetting properties. Plasma processing of materials is also a critical technology in the aerospace, automotive, steel, biomedical, and toxic waste management industries [3]. The use of plasma processing at atmospheric conditioning is fast becoming an intense area of research and application in plasma medicine.
The impact of radicals in cold atmospheric plasma on the structural modification of gap junction: a reactive molecular dynamics study
Published in International Journal of Smart and Nano Materials, 2019
Rong-Guang Xu, Zhitong Chen, Michael Keidar, Yongsheng Leng
which are bond, lone-pair, over coordination, under coordination, valence angle, double-bond valence angle penalty, valence angle conjugation, hydrogen bond, torsion, conjugation, van der Waals, and Coulomb energy, respectively. The detailed meaning of each term can be found in original references [23,24]. Bond order plays an essential role in ReaxFF, which distinguishes between contributions from σ bonds, π-bonds and double π bonds. Bond order needs to be adjusted to compensate for atomic over/under-coordination. The parameterized reactive force field covers more than half of the periodic table of elements and their compounds. Recently it has been extended to complex organic molecules such as DNA and glycine [25]. ReaxFF is optimized to obtain overall good accuracy similar to quantum mechanical calculations but at a much lower computing cost. As for modeling of plasma medicine, ReaxFF has been used in MD simulations to investigate the interaction of ROS with DNA [26], peptidoglycan and lipids [27], as well as liquid water [28]. In this study, we investigated the interaction of plasma species with N-terminal of connexin Cx26 by means of the ReaxFF reactive force field, especially using the C/H/O/N glycine/water parameters developed by Rahaman et al [25].
Dual-mode Dupree turbulence damping of the surface plasma wave
Published in Waves in Random and Complex Media, 2022
Myoung-Jae Lee, Kazuo Takahashi, Young-Dae Jung
In summary, the damping rate of the surface wave propagating on the boundary of half-space turbulent plasma and the effect of Dupree diffusion coefficient on the damping are investigated in this work. Specular boundary reflection condition is employed and the integral dispersion equation for half-space plasma is solved to obtain the wave frequency and the damping rate by using the transverse truncation method. The surface wave is found to support the dual-mode frequency. The damping rate of high frequency mode is found to increase fast as the wave number increases. However, for the low frequency mode, the damping rate diminishes gradually as the wave number increases after passing the peak of damping at a certain value of wave number. The role of Dupree diffusion coefficient may be more important for the damping of low frequency mode, although both damping rates of high and low modes are enhanced by the increase of the value of diffusion coefficient. It would be expected that the surface wave for large thickness in the slab configuration of the plasma bounded by two interfaces corresponds to the surface wave in a semi-bounded plasma. However, the physical characteristics of surface wave in a semi-bounded plasma would be different from those in a bulk plasma due to the spectral reflection condition in the interface of the semi-bounded plasma. Then, the direct corresponding relation would not be obtained for the dispersion relations for the surface and bulk plasma waves. Hence, the investigations on the physical properties of surface waves in semi-bounded plasmas would provide various applications such as surface treatment, microelectronics, plasma chemistry, laser physics, gas detoxification, plasma medicine, etc [2]. The results found in this work by using the transverse truncation method should provide useful information on the damping rate and the effect of Dupree diffusion on the surface waves in a sharply bounded turbulent plasma.