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Advancement in the Fabrication of Composites using Biocompatible Polymers for Biomedical Applications
Published in Atul Babbar, Ranvijay Kumar, Vikas Dhawan, Nishant Ranjan, Ankit Sharma, Additive Manufacturing of Polymers for Tissue Engineering, 2023
Nishant Ranjan, Sehra Farooq, Harnam Singh Farwaha
Polyglycolic acid (PGA), also known as polyglycolide, is a biodegradable and biocompatible aliphatic polyester commonly used in the medical field (Asghari et al., 2017). Ring-opening polymerization can be used to make PGA from glycolic acid. Because of its widespread use as a biodegradable construction material, PGA has been studied in a variety of biomedical domains. In medical applications, PGA-based tissue engineering scaffolds have been used. The PGA nanofibers are used in a variety of tissue engineering investigations. The nanocomposite of PGA and collagen was created by Kobayashi et al. (2016), and within five days of implantation, the PGA collagen nanocomposites were occupied and vascularized, according to their animal model data. Based on tissue engineering research, it has been suggested that PGA polymers might be a good scaffold for cartilage and blood vessel regeneration. Another work focuses on cartilage regeneration, using PGA and collagen to create nanocomposites as scaffolds for generating vascularization. To create scaffolds-stimulating cartilage, PGA-hydroxyapatite (HAp) was used.
Polymeric Biomaterials in Tissue Engineering
Published in Chander Prakash, Sunpreet Singh, J. Paulo Davim, Functional and Smart Materials, 2020
Akhilesh Kumar Maurya, Nidhi Mishra
Polyglycolic acid (PGA) is the simplest linear thermoplastic biodegradable polymer and the member of aliphatic polyesters. PGA was the first synthetic absorbable and biodegradable suture introduced in the early 1970s [59]. Polyglycolide or PGA is a simple and linear aliphatic polyester, which can be reverted to carbon dioxide and water under human physiological environmental condition [60,61]. It can be prepared from glycolic acid by means of polycondensation.
Medical textiles
Published in Textile Progress, 2020
Polyglycolide, or polyglycolic acid, PGA, is a biodegradable linear thermoplastic polymer. The basic structure is glycolide and once polymerized, the polymer can be shaped by extrusion into filaments, pins or rods, melt moulded or shaped by compression moulding. Fibre-reinforced composites have been used to strengthen the mechanical properties of this polymer [142].