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Study on the extraction of grape seed oil by supercritical carbon dioxide
Published in Binoy K. Saikia, Advances in Applied Chemistry and Industrial Catalysis, 2022
In this work, supercritical CO2 fluid technology was used to extract edible oil from grape seeds to find the parameters with the highest extraction rate. The oil content of grape seeds is very high, up to 140.17%, which is comparable to corn and soybeans commonly used to extract oil, so it is a waste of resources if thrown away (Du 2015; Tian 2018). In 2015, China's grape output was 12.628 million tons, making it the second largest producer, indicating it is very important to make full use of its grape seeds to avoid waste of resources. Compared with corn and soybeans, it also contains proanthocyanidins, which can not only facilitate the production of collagen, but also block ultraviolet rays and enhance immunity. Among them, vitamin E has a very obvious skin care effect. Higher levels of unsaturated fatty acids contribute to the prevention of cardiovascular and cerebrovascular diseases. In this experiment, the extraction yield was used as an index to find out the appropriate extraction parameters by designing orthogonal experiments. The second research content is to measure and compare the anthocyanin content in grape seed oil obtained by different extraction processes by using ultraviolet-visible spectrophotometer, and thereby obtaining suitable parameters.
Nanostructured Drug Delivery of Nutraceuticals for Counteracting Oxidative Stress
Published in Bhupinder Singh, Minna Hakkarainen, Kamalinder K. Singh, NanoNutraceuticals, 2019
Shobhit Kumar, Bharti Gaba, Jasjeet K. Narang, Javed Ali, Sanjula Baboota
Vitamin E is well known for its protective action against oxidative stress. It is usually found in many foods such as cereals, meat, poultry, eggs, fruits, and vegetables. It helps in the prevention of digestive problems, cystic fibrosis, sunburn, uveitis, dementia, stroke, rheumatoid arthritis, dysmenorrheal, anemia, cataracts, and many other diseased conditions. The systemic availability of vitamin E depends on plasma lipoproteins, which are responsible for its transportation into the circulation. Blood level of this vitamin is controlled by hepatic system, wherein the transfer proteins play a key role.
Vitamins and Nutrition
Published in Richard J. Sundberg, The Chemical Century, 2017
Vitamin E is synthesized only in plants. Human food sources of vitamin E are mainly vegetable oils, seeds, nuts, and cereal grains. Wheat germ oil is particularly rich in vitamin E. Milk can also be a source if the animals’ diet contains sufficient forage. There is no specific human disease condition associated with vitamin E deficiency, but in rats it leads to diminished reproduction. Humans who are genetically deficient in the ability to utilize vitamin E suffer from neurological disorders.13 Some epidemiological studies have suggested reduced rates of cardiovascular disease in groups with higher vitamin E levels or intake. Vitamin E is an antioxidant and is believed to function as a chain-breaker in lipid oxidation by various oxygen radicals. Vitamin E is frequently used as a supplement both by humans and in animal feed. Vitamin E is also a common constituent of cosmetics. Vitamin E is a case where excess amounts may cause adverse results. Vitamin E can slow blood coagulation, especially if vitamin K level is low, and affect the high-density lipoprotein/low-density lipoprotein (HDLP/LDLP) ratio unfavorably. Retrospective statistical analysis of a number of studies of use of vitamin E alone or in combination with other antioxidants have suggested slight increases in all-cause mortality.14 Long-term clinical studies have been carried out to see if vitamin E supplements reduce the risk of cancer or cardiovascular disease. The result is that they do not.15
α-tocopherol as a selective modulator of toxicogenic damage induced by antineoplastic agents cyclophosphamide and doxorubicin
Published in Journal of Toxicology and Environmental Health, Part A, 2023
Victor Alves de Oliveira, Andressa Naiane Rodrigues Monteiro Fernandes, Lauana Maria dos Santos Leal, Paloma Alves Ferreira Lima, Ana Rafaela Silva Pereira, Irislene Costa Pereira, Helber Alves Negreiros, Joilane Alves Pereira-Freire, Felipe Cavalcanti Carneiro da Silva, Ana Amélia de Carvalho Melo Cavalcante, Francisco Leonardo Torres-Leal, Adriana de Azevedo Paiva, João Marcelo de Castro e Sousa
Vitamin E is a fat-soluble vitamin that plays an important role attacking free radicals (DiVincenzo et al. 2019; Miyazawa et al. 2019). Vitamin E has several vitamin isomers (tocopherols and tocotrienols) (Constantinou, Papas, and Constantinou 2008) that act as antioxidants, including α-tocopherol, which has greater biological activity and acts as adipose tissue protector for preventing lipid oxidation and lipid deposition under blood vessels (Bhatti et al. 2018; Siti, Kamisha, and Kamisiah 2015). In addition, vitamin E has anti-inflammatory, anti-carcinogenic, pro-apoptotic and chemosensitizing properties which are important to block uncontrolled cell cycle of malignant cells (Abraham et al. 2019; Borel and Desmarchelier 2018; Jiang 2014; Sailo et al. 2018; Wiwanitkit and Chaiyasit 2012; Zaffarin et al. 2020).
Production of vitamin A and vitamin E: expression of vitreoscilla hemoglobin gene in Erwinia herbicola
Published in Preparative Biochemistry & Biotechnology, 2022
Vitamin A prevents eye problems and blindness. It prevents skin problems by strengthening the immune system. It also treats ulcers in the digestive system; protects the body against colds and infections in the kidneys, bladder, lungs and mucous membranes.[7] Vitamin E is a nutrient that has important roles in many areas such as skin health, eye health and hormonal order. At the same time, vitamin E, which is one of the vitamins with antioxidant properties, is also very effective in strengthening the immune system.[8,9] Vitamin E, which is also an antioxidant vitamin, prevents them from causing harmful consequences on the body by reducing free radicals. In this way, it reduces oxidative stress, prevents the formation of genetic damage in cells, and helps fight many diseases, especially cancer. Vitamin E, which contributes to the strengthening of the immune system, contributes to the protection of the body against infectious diseases when taken in sufficient amounts.[10] Vitamins also produce several microorganisms owing to genetic engineering and industrial biotechnology.
A waste valorization strategy for the synthesis of phenols from (hetero)arylboronic acids using pomegranate peel ash extract
Published in Green Chemistry Letters and Reviews, 2022
Jangam Lakshmidevi, Bandameeda Ramesh Naidu, Satya Kumar Avula, Anjoy Majhi, Poh Wai Chia, Ahmed Al-Harrasi, Katta Venkateswarlu
Structures of some important phenols have been provided in Figure 1. Chlorogenic acid (1), tannic acid (2), and eugenol (3) are the naturally abundant phenols, with one of the major use as food additives during food processing. These compounds show promising antioxidant, anti-inflammatory, hepatitis C virus (HCV) infection inhibition, and lysozyme-binding properties and the like (30–37). Paracetamol (4) is used for treating aches and pains, showing several other pharmacological properties (38–40). Vitamin E (5) lowers the cancer risk and maintains healthy eyes and prevents heart diseases (41–42). L-tyrosine (6) is a metabolite for the biosynthesis of several alkaloids (43) that have several biologically significant properties (44–45). Moreover, the phenolic groups are the common units in flavonoids, xanthones, aurones, isoaurones, and several other naturally available and biologically important aromatic compounds (46–49).