Toluidine – Knowledge and References

Toluidine

Toluidine is a chemical compound that belongs to the group of aminotoluenes. It can refer to any of the three isomers of toluidine, namely ortho-toluidine, meta-toluidine, and para-toluidine. Toluidine is commonly used in the production of dyes and specialty chemicals, as well as in various industrial processes such as the production of herbicides and dyes.From: Dictionary of Biomedical Science [2019], Handbook of Commercial Catalysts [2019], Overview of biological mechanisms of human carcinogens [2019]

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List of Chemical Substances

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Published in T.S.S. Dikshith, and Safety, 2016

T.S.S. Dikshith

Exposures to O-toluidine cause toxicity and poisoning to animals and occupational workers. It is highly toxic to animals and humans and is rapidly absorbed by oral, dermal, and inhalation by mammals. The acute oral LD50 to rats ranges from 900 to 940 mg/kg. The compound is known to cause adverse effects in workers, which include headache, irritation of skin, eye, kidneys, bladder, and hematuria. O-Toluidine has caused hepatocellular adenoma and carcinoma in experimental laboratory mice and rats.

Overview of biological mechanisms of human carcinogens

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Published in Journal of Toxicology and Environmental Health, Part B, 2019

Nicholas Birkett, Mustafa Al-Zoughool, Michael Bird, Robert A. Baan, Jan Zielinski, Daniel Krewski

ortho-Toluidine is used in a variety of industrial processes including the production of herbicides and dyes. Exposure is highest in occupational settings, with non-occupational exposure predominantly through tobacco smoking and use of hair dyes. ortho-Toluidine has consistently been associated with an elevated risk of bladder cancer in humans.

Isotherm and kinetic modelling of Toluidine Blue (TB) removal from aqueous solution using Lemna minor

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Published in International Journal of Phytoremediation, 2018

Emilia Neag, Dana Malschi, Andrada Măicăneanu

Toluidine Blue (TB), a phenothiazine type dye, has been used in medicine, textile industry, and biotechnology, as a mediator for various reactions, photosensitizer and as labelling agent for organisms identification (Alpat et al. 2008).