Aptamerized silica/gold nanocapsules for stimulated release of doxorubicin through remote two-photon excitation
Published in International Journal of Smart and Nano Materials, 2022
Lih Shin Tew, Tsung-Hsi Lee, Leu-Wei Lo, Yit Lung Khung, Nai-Tzu Chen
The reagents used in this study are listed as follows: Ammonium hydroxide (NH4OH, Sigma-Aldrich, 30–33%), Hexadecyltrimethylammonium bromide (CTAB, Alfa Aesar, 99%), Tetraethoxysilane (TEOS, 98%, Sigma Aldrich, Darmstadt, Germany), Ammonium nitrate (NH4NO3, Sigma-Aldrich), 3-aminopropyltriethoxysilane (APTES, 99%, Sigma-Aldrich), Doxorubicin hydrochloride (DOX, >99%, LC Laboratories), Formaldehyde (37%, Sigma-Aldrich), Thiol-polyethylene glycol-succinimidyl ester (SH-PEG-NHS, Nanocs, PG2-NSTH-5k), Tetrakis(hydroxymethyl)phosphonium chloride, (THPC, 0.96%, Sigma-Aldrich), Phosphate buffered saline (PBS, Thermo Fisher Scientific), ProLong® Diamond Antifade Mountant (Thermo Fisher Scientific), Hoechst 33,342 (AAT bioquest), and YOPRO-1 (Thermo Fisher Scientific). Unless otherwise specified, all reagents were used as received without further purification.